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Powerhouse Biology

@Powerhouse_Bio

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Following
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Statuses
44

On a mission to reboot the human powerplant

San Carlos, CA
Joined July 2024
Don't wanna be here? Send us removal request.
@Powerhouse_Bio
Powerhouse Biology
7 days
First day on site! @arubikscube joined Powerhouse Biology as a Computational Scientist. He’s our trailblazer on multi-modal network models and ML analysis, and he’s set to grow and shape our computational team. We were instant fans: his creative spark and bold move (yep, he
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@Powerhouse_Bio
Powerhouse Biology
14 days
Few things solidify a reputation better than a sticky nickname. 68 years ago this month, Philip Siekevitz called the mitochondrion “a small body which appears to play a central role in the oxidation of foodstuff,” and popularized its now iconic title: the powerhouse of the cell.
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@Powerhouse_Bio
Powerhouse Biology
28 days
Life is beautiful. We want to give people more of it.
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@Powerhouse_Bio
Powerhouse Biology
2 months
We can't wrap our head around how she does it all - our champion CSO @rachel8407 just published "The AI drug revolution needs a revolution" in npj Drug Discovery. Rachel co-founded Powerhouse Biology with a vision to implement AI-guided multi-modal analysis of mitochondrial.
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@Powerhouse_Bio
Powerhouse Biology
2 months
First data in!!. We've transferred into the brand-new office and laboratory space at MBC BioLabs in San Carlos! Huge thanks to the MBC team for moving mountains to get us (and many others) to work, and to @LeicaMicro for helping us hit the ground running with core equipment and
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@Powerhouse_Bio
Powerhouse Biology
2 months
RT @foresightinst: Thanks to everyone who joined our AI x Bio workshop this weekend! 180 scientists, entrepreneurs, engineers, and funders….
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@Powerhouse_Bio
Powerhouse Biology
2 months
RT @BiocomCA: Happy #NewMemberMonday!.👩‍🔬 @Powerhouse_Bio makes precision peptide therapeutics to combat mitochondrial dysfunction.💡 @serna….
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@Powerhouse_Bio
Powerhouse Biology
3 months
Technically challenging and historically siloed from broader genomics and therapeutic innovation, mitochondrial biology is now at the center of converging tools, data, and demand. We are incredibly excited to see @virushunter and @ARIA_research opening up an opportunity space in.
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@Powerhouse_Bio
Powerhouse Biology
4 months
Here we go!!. We’re hiring a Computational Scientist and an Experimental Biologist to join our fast-paced platform therapeutics startup!. We need scientists and engineers who own their work, adapt quickly without losing precision, and stay laser-focused on what truly matters. We.
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@Powerhouse_Bio
Powerhouse Biology
5 months
RT @sethbannon: NIH grants frozen. Discoveries delayed. PhDs pushed out. Academia getting gutted. Innovation must continue. There’s never….
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@Powerhouse_Bio
Powerhouse Biology
6 months
RT @NatureBiotech: A human metabolic map of pharmacological perturbations reveals drug modes of action https://t.co….
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@Powerhouse_Bio
Powerhouse Biology
8 months
New in @Nature: Analysis of 56,434 human mitochondrial genomes through a constraint model for mtDNA. It reveals which positions are highly constrained - that's a huge advance in our understanding of pathogenic variants and mitochondrial disease. Importantly, though, it's also an.
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@Powerhouse_Bio
Powerhouse Biology
8 months
RT @AsimovBio: Over the years, people have asked: What does Asimov do? This is our brief response. At a high level, we think biology is an….
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@Powerhouse_Bio
Powerhouse Biology
9 months
RT @SagerGosai: I’m thrilled to share that our paper “Machine-guided design of cell-type-targeting cis-regulatory elements” was published o….
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nature.com
Nature - A generalizable framework to prospectively engineer cis-regulatory elements from massively parallel reporter assay models can be used to write fit-for-purpose regulatory code.
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@Powerhouse_Bio
Powerhouse Biology
9 months
RT @CultivariumFRO: 🎉 Congratulations to all the #iGEM2024 Grand Jamboree finalists! Your hard work and innovation to push the boundaries o….
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@Powerhouse_Bio
Powerhouse Biology
9 months
2/2.The authors used a bold cross-kingdom synthetic biology approach in which they employed machinery from Mycobacterium and T4 bacteriophage to enable EJ. Using single-cell multiomics (DOGMA-seq, as developed by Eleni Mimitou, Caleb Lareau, Kelvin Chen et al.), they uncovered.
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@Powerhouse_Bio
Powerhouse Biology
9 months
1/2.Engineered human mitochondrial DNA (mtDNA): Yi Fu, Max Land et al. did it in and it's absolutely wild. For context, in contrast to the tech available to manipulate our nuclear genome, we've barely touched human mtDNA. Following recent advances in.
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biorxiv.org
Recent breakthroughs in the genetic manipulation of mitochondrial DNA (mtDNA) have enabled the precise introduction of base substitutions and the effective removal of genomes carrying harmful...
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