Renato Ostuni
@OstuniLab
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Ultra-Professor at San Raffaele Institute, Milan. Immunity, Cancer, Genomics, Gene Therapy, and Ultra-Running. Here and "there" at https://t.co/vllLM9lUHt
Milano, Lombardia
Joined December 2017
Happy to share our latest reflections @TrendsImmuno on our favourite cells: IL-1b+ macrophages 🔥🔥🔥.Molecular, spatial, temporal, functional properties in cancer and beyond. it's all in there from the awesome @NCaronni, @lt_federica and Luca Frosio.
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Out in @ScienceTM! The Naldini lab delivers another masterclass of stem/immune cell gene engineering to deliver cytokines in the TME and boost CAR-T cell activity in glioblastoma. Kudos to @f_rossari @giorgiaalvisi and Nadia Coltella for this important study🔥.
🧵1/.🚨 Just out in Science Translational Medicine @ScienceTM our latest work @NaldiniLab:.We show how tumor-targeted cytokines can rescue CAR-T function and recruit endogenous T cells to fight glioblastoma, the toughest brain cancer. 🔗👇 Here's a thread:.
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RT @f_rossari: 🧵1/.🚨 Just out in Science Translational Medicine @ScienceTM our latest work @NaldiniLab:.We show how tumor-targeted cytokine….
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Neutrophil aficionados, this is THE meeting! Don't miss it🎯.
The wait is over, it’s back! 🧪 .Granulocyte Meeting 2025 | 15–18 Sept | Shanghai. Big science. Big names. Big City. Don’t miss it. 🔗 #Gmeeting2025 #Granulocytes #ThePowerOfMany
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Check this out! Great stuff, as usual from the @iannaconelab.
1/ 🚨 Hot off the press in @NatImmunol: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity. 🧵(1/11).2/
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Great piece @MiriamMerad @WSJ "separate beneficial inflammation, the one that protects us from microbes and from tumors, from the pathogenic inflammation that is enhancing cancer progression, promoting atherosclerosis, promoting damage in the older brain".
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Not just mitosis - the centromere as a site of immune activation 🔥🔥🔥. Viral proteins alter centromere organization and local amplification of DNA -> this is recognized by nuclear cGAS-STING. beautiful stuff by Nicolas Manel lab in @CellPressNews .
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The field of exercise-immuno-oncology is taking off. out now in @NEJM "A 3-year structured exercise program initiated soon after adjuvant chemotherapy for colon cancer resulted in significantly longer disease-free survival".
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We are looking for 1 mid-career scientist (and postdocs) willing to join us as SR-Tiget in Milan. Basic and translational immunology, gene and cell therapy, genome/protein tech, computational biology. all welcome 💚🤍❤️ .check the Call, pls RT!.
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RT @LiabeufDylan: Thank you @OstuniLab, Filippo and the Italian Outdoor Fest. for organising such a cool and informative event! . Last kms….
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📌Join us at the Italian Outdoor Festival this Sunday!. Will speak with @LiabeufDylan ( and ultrarunning legend Filippo Canetta about #immunology #running #exercise #Wellness #scicomm . @MyUniSR @SanRaffaeleMI @Fondaz_Telethon .
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RT @ferrari_sam93: 🚨 What if a single DNA typo could inflame the body and outcompete healthy blood cells?. 🧬 This happens in #VEXAS syndrom….
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RT @LabWaggoner: Review @TrendsImmuno @NCaronni @OstuniLab.IL-1β+ macrophages and the control of pathogenic inflammation in cancer. https://….
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and here's the Sharelink with full access:
Happy to share our latest reflections @TrendsImmuno on our favourite cells: IL-1b+ macrophages 🔥🔥🔥.Molecular, spatial, temporal, functional properties in cancer and beyond. it's all in there from the awesome @NCaronni, @lt_federica and Luca Frosio.
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RT @MatthewD_Park: A must-read review on the recent developments in the field that refine our understanding of IL-1 in cancer development a….
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RT @TrendsImmuno: IL-1β+ macrophages and the control of pathogenic inflammation in cancer #immunology
https://t.co/….
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RT @MiriamMerad: Thank you Renato for a clear and timely review highlighting how IL-1β⁺ macrophages contribute to disease both locally by f….
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RT @Lo_Zanzi: #MustRead. For #TumorImminologyLovers & more, check this fantastic review @OstuniLab @NCaronni &co @TrendsImmuno all about #I….
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RT @Fondaz_Telethon: 1000 persone a Rimini per la XXII Convention Scientifica di Fondazione Telethon. Più di 500 ricercatori finanziati si ….
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