Nicholas Chrimes
@NicholasChrimes
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Anaesthetist | Creator @VortexApproach | Director @UniversalAirway | Co-founder @SafeAirway | Executive Member Airway SIG | Coordinator @EZDrugID
Sydney, Australia
Joined March 2009
Cricoid has been selectively vilified out of RSI in some settings but has more evidence, less risks and a better rationale than any other cited component. So why not do it routinely for all tracheal intubations? Let the games begin. In @Anaes_Journal
https://t.co/DeDP4hNpJY
associationofanaesthetists-publications.onlinelibrary.wiley.com
Click on the article title to read more.
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"Do that thing Nick Chrimes made up, I can't remember what it's called" has to be the best recommendation @dasairway has ever made! π I couldn't be more chuffed.
Just reading the 2025 @dasairway guidelines supplementary materials: https://t.co/WAcyhCLzhC The non-technical skills section is an absolute gold - it offers very useful practical steps how to address the issues may arise at plan A B C and D. ping @NicholasChrimes What is it?
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"Paradox of informed consent" by @NicholasChrimes et al
@valhumphreys51 Found it https://t.co/qCN9WMB5rm
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I accidentally deleted the PUMA Twitter account, so please re-follow. The rest of the guidelines REALLY are coming out in 2026.
Consensus guidelines for preventing unrecognised oesophageal intubation. The most widely supported airway guidelines ever published. Free full text in @Anaes_Journal
https://t.co/fcMbLTlJpB
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@loes_bruijstens @NicholasChrimes @Anaes_Journal In NAP4 & NAP7 more related to intubation than SGA use In famous Warner paper (prevSGA) 60% of aspirations occurred during laryngoscopy or extubation, though I guess confounding is likely
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@NicholasChrimes @Anaes_Journal I agree regarding vilification of cricoid and lack of evidence for (m)any of the other elements of RSI -said as much in a lecture last week There are significant downsides to -predefined induction dose -lack of delay between drugs -early intubation -even use or not of NGT
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@AirwayMxAcademy @NicholasChrimes @Anaes_Journal Rather than reserve Cricoid Pressure (CP) only for RSI, CP, when indicated, will reduce gastric insufflation during BMV! #CricoidParadox
https://t.co/ZTBhzil1i1
@drlauraduggan @AirwayMxAcademy @rosshofmeyr See effect of CP in sealing the Oropharynx- Invaluable during diff.BMV aka the Cricoid Paradox!
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Did some rough maths. There a 4 million anaesthetics given in Australia annually. If 20% of these involve administration of NMBA then using roc vs atrac (or vec) would result in an additional 200 episodes of anaphylaxis per year. Not insignificant.
The chance of having an allergic reaction to a neuromuscular blocking drug is: β’ suxamethonium: ~1 in 1500 people β’ rocuronium: ~1 in 3300 people β’ atracurium: ~1 in 15,000 people Women were up to eight times more likely to have a reaction than men. #anaesthesia #MedTwitter
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@NicholasChrimes @DrRJWebb @AirwayMxAcademy Pholcodine banned in UK March 2023 β¦..but immunologists Iβve spoken to are far from convinced of its relevance to NMB allergy
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Interesting paper. REBOA outcomes not as good as heading straight to theatre. Will this paper change practice?
REBOA = higher mortality (47% vs 36%), more transfusions, longer time to OR. No survival benefit. Check the new study by Hatchimonji et al. https://t.co/RnQGoCdJXI and Jansen's commentary https://t.co/s3qqRcWi6C.
@jhatchmd @dianehaddadmd @pdowzicky @markseamonmd
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Emergency Medicine Registrar teaching today: 2 hours of airway sim then 2 hrs advanced airway classroom and practical including hands on practice with airway visualisation using the aScope in our βlive cadaver labβ Like with kids - you want them to have the things you never had.
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In Australia & NZ you should only be using rocuronium if thereβs a benefit to the patient from its rapid onset. That doesnβt necessarily require it to be RSI, could just be challenging FMV, short safe apnoea time, etc. If you just want to reverse w sugammadex, use vecuronium.
The chance of having an allergic reaction to a neuromuscular blocking drug is: β’ suxamethonium: ~1 in 1500 people β’ rocuronium: ~1 in 3300 people β’ atracurium: ~1 in 15,000 people Women were up to eight times more likely to have a reaction than men. #anaesthesia #MedTwitter
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Come join us for an airway fellowship in 2026 at Gosford Hospital on the NSW Central Coast. DM me for more details.
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@Anaes_Journal Fascinating Quite a different NMBD rate from the UK NAP6 (which only captured grade 3+ (ie life threatening anaphylaxis cases) Reported UK rates -rocuronium 1:17,000 -atracurium 1:24,000 -suxamethonium 1:9,000 They had differing relative -severities and -phenotype of
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The chance of having an allergic reaction to a neuromuscular blocking drug is: β’ suxamethonium: ~1 in 1500 people β’ rocuronium: ~1 in 3300 people β’ atracurium: ~1 in 15,000 people Women were up to eight times more likely to have a reaction than men. #anaesthesia #MedTwitter
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β’ There is a significant difference between the rates of peri-operative hypersensitivity reactions with rocuronium and suxamethonium vs. atracurium. β’ Females may be higher risk than males of reacting to neuromuscular blocking drugs. #anaesthesia #allergy #MedTwitter
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π¨ SAVE THE DATE! π¨π£π’ After the incredible success and glowing feedback from our Winter Airway Workshops, the countdown begins for #GAMC2026! π π
18β19 June 2026 π London Learn from world-class faculty and experience the legendary #GAMC vibe π« The booking link opens soon!
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@Dr__Yield @BJAJournals @dasairway Guidelines do not mandate care, but they do de facto establish standards -these guidelines based on evidence -they recommend default VL -the strength of recommendation evidence is grade A (the highest possible) -the rationale for use of a VL is safety -our standard-setting
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