Robert Parangi MD
@MdParangi
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@dme43989869 @Ace_Archist Because when the tables are turned, people defend the other side, because they have no principles
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@JSG_54 @dr4liberty Agreed. Xylazine is cheap, however, & as long as the scumbag drug pushers are using it in the product that they sell, it will be ubiquitous. I'm starting to think that our government needs to put the amoral pushers out of business by selling street drugs that are tested & cheap.
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@Mrsyumahotrod @thomasjwwalters Simple solutions to complex problems from those with simple minds....
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We just gave our first XR-Buprenorphine injection today. So grateful for everybody who worked to get it arranged and to our first patient. Having every tool available for people with #OpioidUseDisorder is essential. @NewBridgeMedCtr @DebVisconi @dr_gianv
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Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects | Gut
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I second, third, and fourth this. These are evil people.
On this Christmas Season, prayers for the families of the thousands of souls who’ve died of fentanyl overdose. Given the number of dead, it should have long been our central concern. Those who are manipulating the focus to Rx meds for their person gain are unspeakably evil. 🙏
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To all Twitter friends of Dr Debbie: Very sad that she died suddenly Tues afternoon. Due to DEA issues she had been forced to taper off pain meds. Tues suffered a severe all-body pain attack causing heart to stop. Couldn't be stabilized. Pain kills. She cared for you all.
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Chronic pain-induced neuronal plasticity in the bed nucleus of the stria terminalis causes maladaptive anxiety - PubMed
pubmed.ncbi.nlm.nih.gov
The comorbidity of chronic pain and mental dysfunctions such as depression and anxiety disorders has long been recognized, but the underlying mechanisms remain poorly understood. Here, using a mouse...
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Frontiers | Targeting peripheral opioid receptors to promote analgesic and anti-inflammatory actions
frontiersin.org
Mechanisms of endogenous pain control are significant. Increasing studies have clearly produced evidence for the clinical usefulness of opioids in peripheral...
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Impact of Morphine Treatment With and Without Metoclopramide Coadministration on Myocardial and Microvascular Injury in Acute Myocardial Infarction: Insights From the Randomized MonAMI Trial | Journal of the American Heart Association. Interesting
ahajournals.org
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He still won’t credit the opiates. And says he would not have ever started her (maybe after the colectomy he would). The biologicals remain his religion I guess. Or the opiates are his antichrist
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My Crohns pt bled 3 times as she failed different biologicals (13 units transfused 3rd time). GI told her she’ll likely end up with colostomy. Started opiates 5 years ago for pain/fibromyalgia and bleeding did not recur. She showed scientific articles like this to her GI. He
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Physiology, signaling, and pharmacology of opioid receptors and their ligands in the gastrointestinal tract: current concepts and future perspectives | SpringerLink came across this article.
link.springer.com
Journal of Gastroenterology - Opioid receptors are widely distributed in the human body and are crucially involved in numerous physiological processes. These include pain signaling in the central...
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