Serge McGraw
@McGraw_Lab
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Associate prof @UMontreal. Developmental Biologist & Epigeneticist. Embryos, Stem Cells, Organoids #TBRS #FASD Research. https://t.co/2EArKdqnKU
Montréal, Québec
Joined June 2016
What is the long-term impact of loss of sustained DNA methylation maintenance by DNMT1 for molecular and cellular integrity of mouse embryonic stem cells? Thrilled to share the lab’s newest preprint https://t.co/jVkiCsfMwr Amazing effort from @eli__elder and team! 🧵1/11
biorxiv.org
Our research is motivated by the pivotal role of DNMT1 in maintaining DNA methylation, genomic stability, transposable element silencing, and imprinting alongside the extensive utilization of...
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La plateforme GROSSESSE en SANTÉ - Plus de 3 femmes sur 4 prennent des médicaments pendant leur grossesse. Informez-vous! 🚀💊🤰🏾 https://t.co/fyHGUopYDr @Grossesse_Sante @pharm_umontreal @CR_CHUSJ @IRSC_CIHR
lapresse.ca
La majorité des femmes prendront au moins un médicament au cours de leur grossesse, mais elles manquent grandement d’information sur les risques que cela comporte. Devant cette faille, une premi��re...
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Thanks again for the Knowledge Transfer award!!
From October 21-23, the RQR symposium took place. With over 215 participants, sunny weather and a theme focused on artificial intelligence, the symposium was a great success 👏 A big thank you to all the speakers, participants, volunteers, evaluators, chairs and committees!
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🚨 PLUS QUE 24H! 🚨 Le lancement du HUB GROSSESSE en SANTÉ, plateforme pancanadienne sur les médicaments et la grossesse, c’est demain! Mercredi 19 nov 2024 à 13h HE Inscrivez-vous maintenant pour participer à l'événement en ligne ! https://t.co/OZ9INade9l
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👏 Toutes nos félicitations au Dr @DeborahBourchis, cheffe d’équipe de recherche à l’@institut_curie, lauréate du prix Antoine Lacassagne 2024 ! Cette distinction vient récompenser ses travaux novateurs sur les mécanismes épigénétiques impliqués dans la reproduction.
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A universal reference for benchmarking human embryo models was unavailable until Drs. Cheng Zhao (@ChengZh71215605), Sophie Petropoulos (@Scwin2), @fredrik_lanner, and team developed one. 💡 Learn about their comprehensive human embryo reference tool: https://t.co/xIT8l2ElCX
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A Resource developed by the teams of @fredrik_lanner and @Scwin2 provides a transcriptional reference map of human embryonic development spanning the zygote to gastrula stages and a webtool ( https://t.co/sEAmgr0J33) for comparative studies. https://t.co/KvLRqBMXam
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Really excited to share the latest paper from our lab! https://t.co/ny2JmiKq7c Check out our tool and reference here: https://t.co/6SVPtEQrwG A big thank you and great work from the entire team👏🏻🤩 (cont’d…)
nature.com
Nature Methods - This resource integrates different human embryo datasets to create a transcriptional reference map of human embryonic development from zygote to gastrula.
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We are recruiting! Princess Margaret Cancer Centre in Toronto is recruiting an early career cancer research scientist at Assistant Professor level. Apply! Spread the word!
nature.com
Princess Margaret seeks early-career faculty scientists to establish research programs in Cancer Biology - broadly defined.
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Check out our new review! The Two Faces of HDAC3: Neuroinflammation in Disease and Neuroprotection in Recovery https://t.co/pRHtS73jTs
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Latest research from the Teves lab is now out on Biorxiv! "Functional divergence of TBP homologs through distinct DNA binding dynamics" https://t.co/lBeoTvc5dz Here, we examine how conservation is balanced with diversification throughout evolution, using TBP as a case study.
biorxiv.org
The TATA box-binding protein (TBP) is an evolutionarily conserved basal transcription factor common in the pre-initiation complex of all three eukaryotic RNA polymerases (RNA Pols). Despite their...
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What are oncohistones and how do they play a role in cancer? This new article by @WajihJawhar from the @CEEHRC trainee committee gives you an introductory primer! #ThisIsEpigenetics
https://t.co/6Sv7FiZqJW
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Que sont les oncohistones et quel rôle jouent-elles dans le cancer ? Cet article récent de @WajihJawhar du comité des stagiaires de @CEEHRC vous offre une introduction ! #ThisIsEpigenetics
https://t.co/wHDVG1fSig
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🧬 Calling all #researchers! Join us for the Overgrowth Syndromes Alliance Speaker Series. First up: Dr. Harrison Gabel, exploring mechanisms of overgrowth & intellectual disability syndromes. 🧠 🗓️ Nov 22, 2024, 10 AM EST 🔗 https://t.co/66XPRfPSHh Register now!
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Interested in technology development 🤔 Want a stepping stone into the biotech industry with training, secondments & competitive salary? Check out the ARISE2 programme: https://t.co/MsZrYdQTR4 If you are interested in translational applications of #CRISPR… contact me! #job
embl.org
Career Accelerator for Research Infrastructure Scientists
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🚨 The last poster session of #TMM2024 is LIVE! 🚨 Don't miss your chance to visit the brilliant MRM Trainees and check out their groundbreaking work! Come see the next generation of researchers in action! 🔬✨ #MRM #Research #StemCells #RegenerativeMedicine
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Analyzing whole genome DNA methylation data? Our new method MethyLasso is out in NAR! It can help you identify regions with low or partial methylation (LMR, UMR, DMV, PMD, PMD) or differentially methylated regions (DMR) and was benchmarked against others https://t.co/83dtbhDStP
academic.oup.com
Abstract. DNA methylation is an epigenetic mark involved in the regulation of gene expression, and patterns of DNA methylation anticorrelate with chromatin
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Looking forward to this session on stem cell and organoid models of disease, chaired by @THebertMcGill . #TMM2024
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You can now apply to present/attend the next Gordon Research Seminar on Histone & DNA Modifications in beautiful Tuscany in July 2025. @AnnaKnoer & I are thrilled to have @hackettlab as Keynote for the event!
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Our latest paper is out: "Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways"
nature.com
Nature Communications - Here the authors suggest that in Atypical Teratoid Rhabdoid Tumors, EZH2 inhibition triggers a viral mimicry response via the activation of genes with intronic IR-Alu...
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