Max Unfried
@MaxUnfried
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Man of Science 🧬 AI & Gerophysics to understand Aging. 🇸🇬 Rethinking the Fundamentals of Aging & Rejuvenation Biology @TTIScience 🇺🇸
Singapore & Europe
Joined October 2018
Need a „without AI conference“. Only science that is based on deep thought and human ingenuity.
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Moreover - our biology needs ugrades to face the harsh conditions - and a lot of the work done in aging biology on resilience and damage repair will be foundational for this.
"Mars will be very dangerous. And the moon base will be also dangerous. Much more dangerous, and much less comfortable than Earth. People that would go in the early days would have a much higher risk of death than if they stayed on Earth." — Elon Musk
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Last quarter I rolled out Microsoft Copilot to 4,000 employees. $30 per seat per month. $1.4 million annually. I called it "digital transformation." The board loved that phrase. They approved it in eleven minutes. No one asked what it would actually do. Including me. I
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Zurich: I lived there for 3.5 years. It’s a serious city in a serious country. Here’s the most honest breakdown of who Zurich works for and who it really doesn’t. The PROS of Zurich: - Exemplary "functioning country": Nothing is late, broken, or canceled. Ever. You get used
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Great article!
I & @JackScannell13 wrote a manifesto on reviving pharma productivity for @IFP. Public debates focus on improving science or loosening approval. We argue there's real leverage in optimizing the middle part of the drug discovery funnel: Clinical Trials. https://t.co/yZwzDVyWDy
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This is also a way for me to announce I'll be spending much more time focusing on this, so if you're an operator with any ideas on how to improve clinical development, would love to chat!
I & @JackScannell13 wrote a manifesto on reviving pharma productivity for @IFP. Public debates focus on improving science or loosening approval. We argue there's real leverage in optimizing the middle part of the drug discovery funnel: Clinical Trials. https://t.co/yZwzDVyWDy
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We’re launching Astera Neuro, a new neuroscience research effort led by @doristsao as Chief Scientist. Our aim is to unravel a profound scientific mystery: how the brain transforms sensory inputs into conscious experience. Advancing this work could illuminate the computational
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"Biologists, however, while gratified to be told that physicists admit that biology offers problems which actually need thinking about, still remain doubtful whether physicists have realized just how challenging these problems really are." CH Waddington (Towards a Theoretical
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Stochastic thermodynamics is next.
Quantum mechanics has gone from a theory in test to becoming the foundation of new technologies. Learn more in a new #SciencePerspective that looks at the last 100 years of #QuantumMechanics: https://t.co/dJVd43rqZm
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He should try a bit more of biotech especially companies trying to solve aging. That way he can play basketball for longer.
Kevin Durant has a pretty impressive investment track record himself, let's take a look: Invested in Whoop Series B in 2017 (valued at ~$100M), now valued at $3.6B - a ~36x return Invested in Robinhood Series D in 2018 (valued at ~$5.6B), now valued at $119B - a ~21x return
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Some very interesting and valid points in there that are relevant for organizations in the aging field - and how to intersect with philanthropy. Also great to see the TIME initiative highlighted in here that tries to bring more undergrad students into the aging field.
📙 New playbook | Emerging scientific fields face make-or-break moments early on. Our latest, with @sparkclimate & @CascadeClimate, shares the levers for philanthropists & innovators to catalyze new scientific domains. Featuring case studies from aging biology, climate
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Maximum lifespan has not moved at all though. Time to change that.
Science and medicine doubled life expectancy over the last century.
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Aging biology sits on maths.
- Programming sits on maths. - Algorithms run on maths. - Every AI model is maths. - Machine learning is maths. - Deep learning is maths. - Graphics are maths. - Simulations are maths. - Cryptography is maths. - Blockchain is maths. - Data science is maths. - Optimization is
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Elon is right. In an almost comical way, his fear, because of gerontocratic leadership in the aging and life extension field radical life extension and the path to immortality will be delayed and take much longer to accomplish. When leadership of the largest aging institutes
The concern that life-extension could lead to cultural stagnation is worth discussing @elonmusk @MarioNawfal Hopefully, if we reverse aging we improve cognitive flexibility, but we don't know yet. Working on a piece on ethical implications of longevity science. Stay tuned!
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I think I can build a bot that generates comics like this from live tweets. Worth doing? @JellyfishDAO maybe we should go straight to video?
The problem is that we have a lot of data on aging, and this creates the illusion that we have enough data to assemble a drug. We say: “Look, this thing changes with aging — let’s fix it, and aging will slow down.” But the truth is that everything in the body changes with aging,
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