Manchester Brain Bank
@MancBrainBank
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Manchester Brain Bank provides human brain tissue samples to #neuroscience researchers worldwide. Part of @FBMH_UoM and sits within @DNS_UOM. Admin is @MBB_Andy
Joined April 2023
Are you a #neuroscience researcher looking for access to human brain tissue samples to use in your research? Visit https://t.co/RBoJwZ0mwG to find out how we can help!
sites.manchester.ac.uk
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Congratulations to our collaborator, Liam Walker, on being awarded the @NCAresearchNHS Star of the month!
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Check out our recent paper in @braincomms: C9orf72 dipeptides activate the NLRP3 inflammasome šš»šš»šš» With @choyle22, @mere_conjecture, @ComorbidCath, @DNS_UOM, @GJBrainResearch & funded primarily by @AlzSocResearch
Rivers-Auty et al., find that C9orf72 dipeptides cause neuroinflammation in frontotemporal dementia and amyotrophic lateral sclerosis, and highlight the inflammasome as a therapeutic target. Please read the full paper at: https://t.co/Spt043wEJM
@DrSarahRyan
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PhD opportunity - Investigate the Role of Neurovascular Potassium Channels in Aging and Alzheimer's Disease with @GinnyHawkins4, @MBB_Andy and the rest of the specialised supervisory team! https://t.co/n5GPbMRHZa
findaphd.com
PhD Project - The Role of Neurovascular Potassium Channels in Aging and Alzheimer's Disease at Manchester Metropolitan University, listed on FindAPhD.com
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New paper: Our findings suggest that anti-AĪ² therapies are more effective if given before AĪ²3pE-42 deposition. https://t.co/qig00JijA4
life-science-alliance.org
The amyloid Ī² peptide (AĪ²), starting with pyroglutamate (pE) at position 3 and ending at position 42 (AĪ²3pE-42), predominantly accumulates in the brains of Alzheimerās disease. Consistently, donane...
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New publication - Depression in older adults and its associations with sleep and synaptic density. https://t.co/465UvMJvMH [ https://t.co/xscvm01DYj]
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Pick's Disease Presenting as Tremulous Parkinsonism with Limited Levodopa ResponseāA Rare Cause of Corticobasal Syndrome - Bhattacharjee - Movement Disorders Clinical Practice - Wiley Online Library
movementdisorders.onlinelibrary.wiley.com
Background Corticobasal syndrome is a clinical diagnosis and common pathological causes are corticobasal degeneration, progressive supranuclear palsy and Alzheimer's disease. Objectives We would l...
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Another interesting clinico-pathological case study using tissue from @MancBrainBank
https://t.co/TbI0r8As6I
movementdisorders.onlinelibrary.wiley.com
Background Corticobasal syndrome is a clinical diagnosis and common pathological causes are corticobasal degeneration, progressive supranuclear palsy and Alzheimer's disease. Objectives We would l...
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New paper alert! Blocking Hippo to boost cognition:
science.org
Blocking its sequestration by Hippo pathway kinases shifts WWC1 to neuroreceptors that promote learning.
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Registration is open for our āIHC workshop: Post-mortem human brain tissueā š May 2nd 2024 ā° 9am CDT Ā· 3pm BST Ā· 4pm CEST š„ Via Zoom Register early to secure your free place: https://t.co/4A5yo6dpyG
@MancBrainBank #ProteintechEvents #Immunohistochemistry #Neuroscience
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**NEW PAPER ALERT** Delighted for the first work from the Pickās disease International Consortium (PIC) to be published in Lancet Neurology.. (1/12)
thelancet.com
The Pick's disease International Consortium provides an opportunity to do large studies to enhance our understanding of the pathobiology of Pick's disease. This study shows that, in contrast to the...
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Tissue from Manchester Brain Bank was utilised in this very important study https://t.co/501kUSGIVc
thelancet.com
The Pick's disease International Consortium provides an opportunity to do large studies to enhance our understanding of the pathobiology of Pick's disease. This study shows that, in contrast to the...
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Self-reported late-life hypertension is associated with a healthy cognitive status and reduced Alzheimer's disease pathology burden: https://t.co/IM8i0xM5wz
pubmed.ncbi.nlm.nih.gov
Our findings suggest that late-life hypertension is associated with less severe AD pathology. We postulate that AD pathology may be promoted by reduced cerebral blood flow.
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Great to have been involved in this important work led by @jakobhartmann28Ā andĀ @GassenNils. https://t.co/lIvRBvmd2h
nature.com
Nature Communications - Secretory autophagy (SA) plays a crucial role in neuroinflammation-driven neurodegeneration, through SKA2 and FKBP5. SKA2 regulation of SA can inhibit IL-1Ī² release....
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Apolipoprotein-E genotyping in formalin-fixed and paraffin-embedded post-mortem brain tissue #neurodegeneration
https://t.co/if0xsVeseh
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Latest paper from the team at MBB! ApolipoproteināE genotyping in formalināfixed and paraffināembedded postāmortem brain tissue
onlinelibrary.wiley.com
Formalin-fixed paraffin-embedded brain tissue held in tissue banks constitutes a valuable research resource, especially when associated with clinical annotations and longitudinal psychometric...
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The countdown is on to the Jeff Showcase 2024! We're really looking forward to welcoming everyone this Friday at Hyatt Regency Manchester. All the details, from venue to programme can be found here: https://t.co/LNVQ9PoU5D See you there! #Jeffshowcase2024
eventbrite.co.uk
A showcase of the pioneering research happening in the centre.
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My buddies @MancBrainBank just reminded me of this nice wee paper showing that extended post mortem delay does not meaningfully impact metrics of tissue quality. https://t.co/bIoIqA6BXC
link.springer.com
Acta Neuropathologica -
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Itās the NIHR Great Northern Research Conference today in Manchester @alishaneuro @stu_art_here & @josiemthomas are manning our exhibition stand. Come and say hello! #GNRC2023
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Senior Lecturer Dr Claire Troakes showing Sophia how Alzheimerās Disease looks under the microscope! #AD #neurotwitter #neuroscience #kclbrainbank
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