Alessandra Magistrato
@Magistrato_Lab
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Research Director, CNR-IOM @ SISSA, Head of Laboratory for Computational Chemistry and Biochemistry https://t.co/UWWjeIIITL
Trieste, Italy
Joined May 2021
Our work entitled 'Plasticity of the cytotoxic Nep1-like protein enables promiscuity in binding to its lipid receptor glycosylinositol phosphorylceramides' has been published on Science Advances @ScienceAdvances! In collaboration with @GAnderluh read ๐ https://t.co/GZM0OkJRBn
science.org
Microbial effectors Nep1-like proteins bind to different plant sphingolipids and disrupt di- and monocot model lipid membranes.
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๐ข Save the Date! We are thrilled to announce that the Congress of our Division will be held in Palermo. ๐๏ธ September 16-18, 2026. See you next year in Sicily !โ๏ธ ๐๏ธAs always, scholarships will be available for young researchers. The website will be available soon! #DCSB2026
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Our new review entitled 'Decoding Spliceosome Dynamics through Computation and Experiment' has been published on Chemical Reviews @ACSPublications Congrats to @pokorna_pavlina, @Seb_Fica and Jana Aupic! https://t.co/EYVQQibRzx
pubs.acs.org
RNA splicing is orchestrated by a complex and exceptionally dynamic RNAโprotein machine, called the spliceosome. Stepwise, large-scale structural and compositional remodeling of the spliceosome...
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It's a pleasure to host our last invited speaker, Gregor Anderluh @GAnderluh National Institute of Chemistry, Ljubljana @kemijski talking about how the structure of protein nanopore reveals intricate protein-lipid and lipid-lipid interact #DCSB2025
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The first editon of our Angelini Pharma Prize for Best Master Thesis ๐
was won this year by Silvia Oliveti! @UNI_FIRENZE @cerm_cirmmp she will talk about novel methods to investigate multidomain proteins #DCSB2025
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The winner of the first editon of our Angelini Pharma Prize for Best PhD thesis ๐
is Francesco Rinaldi @DrReynolds93 @IITalk talking about the study of BRCA2-RAD51 interactions through an integrated biophysical and structural biology approach #DCSB2025
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We start the first day of the conference with Kourosh Ebrahimi @KingsCollegeLon talking about metalloproteins in immune response and platform for developing #DCSB2025
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We open the second day of our conference with Monika Fuxreiter @UniPadova talking about fuzzy protein interactions in the cell #DCSB2025
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๐ฃ The program for #DCSB2025 is out!! We wait for you all in the beautiful city of Trieste the 18th of June! https://t.co/xQYu22EoFY
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Just published in @NatureComms our new paper integrating #MD and #cryoEM data to construct structural ensembles of complex #RNA macromolecules ๐โจ๐ฅณ https://t.co/wwXCN0HHZ9. Excellent work by @ElisaPos with @BussiGio @BonomiMax @PJanosJr N. Toor, D. Haack
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Check out the great selection of invited speakers! @RommieAmaro, @jessica_compbio, @GBhardwaj8, @BonomiMax, Roberto covino, @arneelof, @grudinin, @Magistrato_Lab, @ChristineOrengo, @Joana_MPereira, Maya Topf, Sameer Velankar, @BasileWicky More info: https://t.co/VInIvBhr1B
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๐ธDomenica 11 maggio 2025 | Festa della Mamma ๐ฌLโazalea della Ricerca di @AIRC_it sboccia in oltre piazze 3.500 piazze per la salute delle donne. Scoprite la piazza piรน vicina su https://t.co/GHJMfZFWEZ
#AzaleadellaRicerca
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Just published our new paper on Identification of a new Small Rho GTPase Inhibitor Effective in Glioblastoma human cells. Check it out! https://t.co/ZilVqt3acK. Work done by @AngelaParise3, in collaboration with @UniTrieste @uniud @IC_CNR
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๐ข Last week left for abstract submission!! ๐ข Last week left for "Best PhD Thesis" "Best Master Thesis" and "Italfarmaco Prize"!! ๐ 18th-20th June 2025 Trieste #DCSB2025
๐ข Registrations for #DCSB2025 are open! ๐ฏ Key Deadlines: ๐ Abstract submission & Early-bird registration: March 24 ๐ฐ 25 fellowships available for non-tenured under 35 members! Apply by March 31 ๐ 18th-20th June, 2025, Trieste ๐ More info: https://t.co/SpqJ1EgJxr
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Happy to share our latest perspective on the use of molecular simulation in SARS-CoV-2 research. Grateful for the collaboration with amazing scientists. You can also find it on the supplementary cover!๐ ๐ Read here: https://t.co/xMLpJeh4RL
Our review โA Reflection on the Use of Molecular Simulation to Respond to SARS-CoV2 Pandemic Threatsโ, in collaboration with the groups of @RommieAmaro, @AdrianMulholla1, @alessio_lodola and Carlos Simmerling just available as open access https://t.co/sabP6zYoDw
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๐ข Our article calling for a #FAIR database for #MolecularDynamics simulation data has now been peer-reviewed and published in @naturemethods ๐ Read it here: https://t.co/2VXy3pgepZ ๐ Support the statement: https://t.co/7vp58TPy1A
#MDDB #FAIRdata #collaboration
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See our latest paper in @NatureComms, by @LucaTorielli @FedericaGuarra Stefano Serapian @GestwickiLab. We show how pathogenic mutations disrupt dynamics, rewire allosteric routes and impair function in chaperone Hsp60. #CompChem #MolecularBiology
https://t.co/2v3mD0nFKu
nature.com
Nature Communications - Mutations cause impairment of function in the chaperone Hsp60. Here, the authors investigate their impact with MD simulations from the monomer to the 28-mer complex, and...
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We're still accepting applications for poster presentations at the CECAM conference "RNA We're still We are sill accepting applications for poster presentation at 'RNA Modelling Across Scales" conference. Apply now: https://t.co/vohRDdDOVo Organized with @BussiGio @devivo_marco
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