Luis Lopes
@LuisRLopes77
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Consultant Cardiologist and Associate Professor - Inherited Cardiac Disease and Cardiac MRI- Barts Heart Centre/University College London
London
Joined July 2019
Not all myocarditis is viral. Pleased to share one of our interesting cases: Isolated Right Atrial Myocarditis Secondary to Listeria Monocytogenes https://t.co/tXd4qg753g
@JACCJournals @oliverguttmann @SekhriNeha @NHSBartsHealth
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A reunião anual do ESC Council of Cardiovascular Genomics terá lugar na Faculdade de Medicina da Universidade de Lisboa, a 5 e 6 de dezembro de 2025, e abordará as mais recentes novidades no tratamento das doenças cardiovasculares hereditárias, incluindo terapêutica genética, com
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🧬💖You are still on time to send an abstract or register with an early fee to the ESC CardioGenomics conference in Lisbon! Share you science with top researchers from across Europe 🇪🇺 🗓️Abstracts deadline: 16 September 25 🗓️Early fee registration: 13 October 25 See you there!
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ESC Cardio Genomics 2025, Lisbon 5–6 December. Focus on precision and genetic therapy in inherited cardiovascular diseases. Workshops, lectures and debates. Register now to secure your spot / submit your abstract by 9 September. https://t.co/OWT7OQGp31
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Analysis of cardiomyopathy genes in septic cardiomyopathy: tested but did't find the association with rare variants in cardiomyopathy genes present in other "acquired" cardiomyopathies. @RevEspCardiol. would be nice to see data from other groups https://t.co/Jlsd7rycJ9
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🚨NEW ARTICLE🚨 Assessment of myocardial work in sarcomere gene mutation carriers, healthy controls and overt nonobstructive hypertrophic cardiomyopathy: https://t.co/BpZU4OkxcD
@carlammpr
@drgeorgejoy
@miltosmd
@Ksavvatis
echo.biomedcentral.com
Background Hypertrophic cardiomyopathy (HCM) is defined by unexplained hypertrophy and often characterized by diastolic and systolic dysfunction. HCM patients are known to have impaired left ventri...
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🚀 Excited to share a new tool based on our @JACCJournals study! https://t.co/C7pY4Jpekh 🔍 https://t.co/hM4llnuWYh provides left ventricular hypertrophy (LVH) MWT threshold values and Z-scores based on age, sex, & BSA.
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Clinical utility and implementation of polygenic risk scores for predicting cardiovascular disease 💔. A clinical consensus statement of the ESC Council on Cardiovascular Genomics, the ESC Cardiovascular Risk Collaboration, and the European Association of Preventive Cardiology 👉
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A novel demographic-adjusted personalised approach to measure wall thickness is an important step towards a more accurate / less biased diagnosis of hypertrophic cardiomyopathy. Very glad to be part of this important study led by @HunainShiwani (congratulations!) & @JccmoonMoon
🔬New in @JACCJournals: HCM diagnosis criteria show unexpected demographic bias. Study of 50,000+ hearts reveals current thresholds create 8:1 male-female ratio Proposing demographic-adjusted thresholds to improve diagnosis🫀 https://t.co/GoRmh9eGmC
@UCL_ICS @NHSBartsHealth
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Reassessment and reclassification of variants of unknown significance in patients with cardiomyopathy https://t.co/4KCABA0PRv - how (and how often) should an ICC department approach VUSes? Work led by our @NHSBartsHealth ICVD genetic counsellors
jmg.bmj.com
Background The utility of diagnostic genetic testing in cardiomyopathy has grown significantly, due to the discovery of novel genes and greater awareness among healthcare professionals. However, a...
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We analysed mitochondrial variation in cardiomyopathy patients from 100K genomes project and found the HCM causing m.4300A>G in 0.6% of (previously) genotype-"negative" HCM patients https://t.co/p19gYPe83I - shall we include it in the testing panels? @RobPitceathly @w_macken
humgenomics.biomedcentral.com
Background A significant proportion of cardiomyopathy patients remain genetically unsolved. Our aim was to use the large genomes cohort of the 100,000 genomes project (100KGP) to explore the propor...
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Promises and challenges of gene therapy in heart failure and cardiomyopathies in a scientific statement of the ESC @escardio HFA, WGMPD and Council on Cardiovascular Genomics https://t.co/Roe5IquEBu. Pleased to have contributed to this document on an exciting and important topic
onlinelibrary.wiley.com
Gene therapy has recently become a reality in the treatment of cardiovascular diseases. Strategies to modulate gene expression using antisense oligonucleotides or small interfering RNA are proving...
🗞️ Gene therapy in #HeartFailure : #HFA , @escardio Council on #CV genomics & WG Myocardial & Pericardial Diseases Scientific Statement @ESC_Journals @GiuseppeGalati_
@AmrAbdin10 @HanCardiomd
@HFA_President
https://t.co/DYN6lxOrzz
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Glad to contribute to this study by @RichardB_KCL @munroe_patsy et al, going beyond imaging of volumes and mass : genetics of biventricular shape. 43 loci, 14 unreported for cardiac. Principal components of shape associate with cardiometabolic disease.
nature.com
Nature Communications - Heart shape is heritable and potentially linked to cardiometabolic conditions. Here the authors perform GWAS on principle components of ventricular shape to identify 43...
📢Hot off the press! Out latest study investigating the genetics of biventricular shape and their association with cardiovascular disease is just out @NatureComms 👇👇👇 https://t.co/5yVjQFsGeS
@munroe_patsy @alyoung62 @RichardB_KCL
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Arrhythmic risk stratification in ring-like scar (gene negative and positive) https://t.co/WU8fvEE95f led by Elena Biagini Bologna’s group with interesting results showing primacy of the ECG. Includes London cohort and other collaborators @IacopoOlivotto @AnaRitaMoura5
academic.oup.com
AbstractAims. Left ventricular (LV) ring-like scar on cardiac magnetic resonance (CMR) has been linked to malignant arrhythmias in patients with non-ischae
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Cardio Genomics Conference 2024 December 6-7 in Antwerp, Belgium. Join us for the latest on cardiovascular genomics ! @rbarvil @BondueAntoine @fdefrutossemi @KristinaHaugaa @jpkaski @DAntonakaki @fernidom
Only two days left to save on registration for the Cardio Genomics Conference 2024 happening on December 6-7 in Antwerp, Belgium. Don't miss out on this opportunity to expand your expertise in the field of cardiovascular genomic medicine and connect with peers from around the
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Share your scientific expertise in the field of cardiovascular genomic medicine. The deadline to submit your abstract has been extended to 11 September. Submit today and register to join us in Antwerp on 6-7 December! https://t.co/nu2ApCgpi6
#CVD #CardioGenomics
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Great study on TTR variants in #UKB @LuisRLopesDr
https://t.co/squg9KwBjU Congrats @DukeCardFellows 🌟@jregan2012 on leading excellent editorial in @JAMACardio & 🙏 @MariannaFonta11 for collaboration! https://t.co/3XUGmaMjtu
@DukeHeartCenter @DukeHrtFailure @DukeMPI @Duke_CTSI
jamanetwork.com
Transthyretin amyloidosis (ATTR) is an underdiagnosed and undertreated systemic disease secondary to deposition of misfolded transthyretin (TTR) proteins, including in the heart and peripheral...
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Listen to an interview with JAMA Cardiology authors @LuisRLopesDr and @senthil_selv on their recent articles hosted by @sday_hcm. Find the episode on @AMAEdHub.
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More people in the UK are at risk of a hereditary form of cardiac amyloidosis, a potentially fatal heart condition, than previously thought, finds a new study led by @LuisRLopesDr @UCL_ICS with @QMUL analysing the genes of nearly half a million people
ucl.ac.uk
More people in the UK are at risk of a hereditary form of cardiac amyloidosis, a potentially fatal heart condition, than previously thought, according to a new study led by researchers at UCL and
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The prevalence of heart amyloidosis related to transthyretin gene variants is higher than expected, Carrier status ~1/1000 overall and ~4% in those with African ancestry. This is an important under-diagnosed and under-treated condition. https://t.co/sRecCWinih from @uk_biobank
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