🔥 #FERRIC_HF substudy: #FerricDerisomaltose augments intrinsic skeletal muscle electron transport chain activity in #HF 🦾 IV iron ⬆️ skeletal muscle mitochondrial function #HFUA 🫀 @AndrewJSauer @DrMarthaGulati @ShelleyZieroth @DrRajivsankar https://t.co/VYfyZ8X5Et

🗞️ Ferric derisomaltose augments intrinsic skeletal muscle electron transport chain activity in #heartfailure: A FERRIC-HF II molecular substudy @ESC_Journals @GiuseppeGalati_ @AmrAbdin10 @HanCardiomd https://t.co/NWYwL1Bu34

Low-dose digoxin improves cardiac function in patients with heart failure, preserved ejection fraction and atrial fibrillation – the #RATE-AF randomized trial https://t.co/d5I2E7ltLI #EJHF @ESC_Journals @HanCardiomd @AmrAbdin10 @GiuseppeGalati_

🔥 #G_CHF study :17321 #HF patients from 40 high/middle/low-income countries Risk of death ☠️ ✅ Independent of #LVEF ✅ Significantly change by #RV dilation & function 🔬 #HFUA 🫀 @AndrewJSauer @DrMarthaGulati @MicheleEmdin @iamritu @ESC_Journals https://t.co/16S32oRxqL

🗞️ The risk of death according to #LVEF & right ventricular dilatation in 17 321 adults with #heartfailure from 40 high-, middle- & low-income countries – A Global Congestive #HF (G-CHF) study @ESC_Journals @GiuseppeGalati_ @AmrAbdin10 @HanCardiomd https://t.co/seagikmi6Y

Acute heart failure in non-cardiac surgery: A clinical consensus statement of the Association for Acute #CardioVascular Care (#ACVC) and the Heart Failure Association (#HFA) of the #ESC https://t.co/TzYXxsSE4c @escardio @HFA_President @EJHFEiC @ACVCPresident @ESC_Journals

“Patient-specific modifiers of survival benefit in cardiac resynchronization therapy - A multicentre interaction analysis” Take a look at #ESCHeartFailure👉 https://t.co/LGZT8Izlgm @EJHFEiC @JanBiegus @Ppponikowski #HFA_ESC @hvanspall @ShelleyZieroth @FudimMarat @gcfmd

CV outcomes with #tirzepatide in heart failure with preserved ejection fraction (#HFpEF) associated with #obesity #EJHF @escardio #ESCCongress @ESC_Journals @EJHFEiC https://t.co/wcKvz1kZ9t

@BiykemB @SJGreene_md @gcfmd @FH_Verbrugge @MarcoMetra @GianluSava @JavedButler1 @FrancescoPaneni @afgcicero @MicheleEmdin @SeguraCardio @TomLuscher @AnastasiaSMihai @iamritu @radcliffeCARDIO @BayerItalia 📜 ⬆️ 5. After the #VICTOR + #VICTORIA pooled analysis #Vericiguat will be a 2nd line drug in ambulatory #HFrEF and a 1st line drug in #WHF (Level of evidence I for #WHF and IIa for ambulatory #HFrEf) 🫀 #HFUA https://t.co/kWMvKJmpUj #ESCcongress https://t.co/ME5PQ32hLH

@gcfmd @BiykemB @SJGreene_md @FH_Verbrugge @MarcoMetra @GianluSava @JavedButler1 @FrancescoPaneni @afgcicero Yes you are right #Vericiguat too after a #WorseningHF event but try to explain this from a pathophysiological side I think that this effect on #HHF does not pass through a natriuretic & diuretic effect but more through a anti-remodeling effect It is a speculation 😉

@BiykemB @SJGreene_md @gcfmd @FH_Verbrugge @MarcoMetra @GianluSava @JavedButler1 @FrancescoPaneni @afgcicero 📜 (#VICTOR profile). This is proven also by a reduction of benefit in highly congested patients with a #NTproBNP value > 6000 pg/mL 4. #Vericiguat is beneficial mostly on an #HF_event within the #WHF profile @MicheleEmdin @SeguraCardio

📜⬇️ 2. #VICTOR + #VICTORIA pooled analysis shows a protection on #CV_death #All_cause_death #SCD #HF_death across the spectrum of #HFrEF severity (#VICTORIA alone was likely underpowered to detect a benefit on mortality) 🫀 #HFUA https://t.co/kWMvKJmpUj #ESCcongress

@BiykemB @SJGreene_md @gcfmd 📜 3. The benefit of #vericiguat is more similar to that of a #beta_blocker, which is higher on #myocardial_remodeling & hard outcomes than on #HHF, this is because of poor natriuretic & diuretic effect (different from #SGLT2i #ARNI or #MRA), especially in ambulatory pts #HFUA

🔥 #VICTOR + #VICTORIA 💡 #Vericiguat Results are published, interpretations are more complex My take: 1. #Vericiguat is an effective & safe drug in #WorseningHF #Tweetorial 📜⬇️

What's new in #HeartFailure ? July 2025 https://t.co/PAVn50tZgE @ESC_Journals @EJHFEiC @escardio

Serial assessment of left ventricular ejection fraction for the management of heart failure: Unnecessary and unrealistic? https://t.co/JtdDaelZiW #EJHF @HanCardiomd @AmrAbdin10 @GiuseppeGalati_

@HFA_President @escardio @MarcoMetra @jozinetm @slumberbell @AmrAbdin10 @WilfriedMullens @corneliacrm @HanCardiomd @SotiriaLiori @_antocannata @h_arfsten @GTersalvi @hvanspall And clearly do not miss Hotline 1, Friday 11-12.00‼️ ➡️ Main results of the #DIGIT_HF trial investigating #Digitoxin vs Placebo in #HFrEF🔥 @SamiraSoltaniMD @ShelleyZieroth @escardio #ESCCongress #heartfailure @slumberbell @GiuseppeGalati_ @EJHFEiC

🔥 #REALIZE_K : Sodium Zirconium cycloSilicate, hyperkalaemia & #spironolactone in #HFrEF 🧂 Highlighting the opportunity offered by this enable to introduce #MRA 🍀 #HFUA 🫀 @AndrewJSauer @DrMarthaGulati @markcpetrie20 @MicheleEmdin @ESC_Journals https://t.co/VkPTA2dfex

Sodium zirconium cyclosilicate, hyperkalaemia, and spironolactone optimization in #heartfailure with reduced ejection fraction: The #REALIZE_K open-label run-in phase @ESC_Journals @GiuseppeGalati_ @AmrAbdin10 @HanCardiomd https://t.co/YFkRRa39cT

HFA scientific statement : Systematically identifying and addressing the multifaceted barriers that hinder early recognition and referral for advanced #HF care @kevin_damman https://t.co/8bGkSfC92l #EJHF @HanCardiomd @AmrAbdin10 @GiuseppeGalati_ @ESC_Journals