Henry Han
@HanCardiomd
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Cardiologist MBBS, MD, FACC, FESC | Physician-Sci & Researcher MPH | #HeartFailure 🧑⚕️| #HFA & #EACVI Committee @escardio | Content Catalyst @TCTMD
USA | Earth 🌎
Joined July 2017
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NIH funding rates for early-career researchers plunged in 2025, new data show https://t.co/RWqf8lfBE9 via @statnews
@AJIAorg
statnews.com
A Trump administration change to how NIH awards grants has sharply reduced early-stage investigators’ odds of securing funding.
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#OPTIPHARM-HF (N=3054, 32 Italian centers): Mean age: 69 ± 12 years | 25% female 📍56% HFrEF / 21% HFmrEF / 23% HFpEF. HFrEF on #GDMT: BB 90%, ACEi/ARB 19%, ARNI 61%, MRA 72%, SGLT2i 69%. 📍Quadruple therapy ↑ from 47% → 64% after 1st visit (p<0.001). 📍#SGLT2i use ↑ to
Contemporary medical therapy for heart failure across the ejection fraction spectrum: The #OPTIPHARM-HF registry https://t.co/fWZLdh9xlX
#EJHF @ESC_Journals
@HanCardiomd @AmrAbdin10 @GiuseppeGalati_
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📌 Which medications should we avoid in HF patients ⁉️ This position 🗞️ provides a very practical guide in daily clinical practice. 📄 A must-read for clinicians caring for HF pts. 🔗 https://t.co/0YdRsmR0Xh
@EJHFEiC @AmrAbdin10 @GiuseppeGalati_ @HanCardiomd #EJHF
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Insurance Coverage and Pricing of Weight-Loss Drugs in the United States https://t.co/zjbdzWXtmO
@NEJM
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🗞️ Combination diuretic therapy in acute heart failure: A systematic review and meta-analysis @ESC_Journals @GiuseppeGalati_
@AmrAbdin10 @HanCardiomd
https://t.co/UHj1x7lIV1
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Not All Hospitalized Heart Failure Patients Are the Same: A New Worldview https://t.co/VOxNEF9BbI
@JACCJournals
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PRECISION (CKD + resistant HTN): 📍Office SBP ↓ 16.6 mmHg, Nighttime SBP ↓ 13.8 mmHg at week 4 📍Albuminuria ↓ 59.6%, maintained to week 36; well tolerated, early edema most common #PRECISIONstudy #CKD #Hypertension
https://t.co/14Epqgbd9S
@HyperAHA
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🚫Harmful Drugs in Heart Failure!💊 A position 🗞️to guide drugs that may cause or exacerbate HF 👉 https://t.co/P41ljOTJdg
@JBauersachsMD @SulemanAktaa @JavedButler1 @mvaduganathan @GianluSava @HFA_President @JanBiegus @MagdyAbdelhami7 @NicolasGirerd @WilfriedMullens
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4/ What unites us is not only our passion for imaging, but our shared commitment to clinical excellence and the care of patients we deeply care for. This spirit was felt throughout the congress.
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1️⃣ How to use GLP-1 RA in patients with #HeartFailure? New #EJHF expert consensus document, a thread🧵: 📍Eligible pts: #HFpEF + #obesity (BMI ≥30 kg/m2) 📍Avoid/caution: #HFrEF, #worseningHF, #ESRD, prior pancreatitis, severe GI intolerance 📍Start low, titrate every 4 weeks
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2️⃣ GLP-1 RAs may play different roles across the #HeartFailure continuum: 📍Stage A (at-risk): #cardiometabolic benefits may prevent transition to #HF 📍Stage B (pre-HF): weight loss & metabolic improvement may slow HF progression 📍Stage C: reduce weight, improve symptoms in
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📌Diagnosis and Management of Cardiovascular Adverse Effects of Targeted Oncology Therapies 2025 @ACCinTouch Concise Clinical #Guidance
#CardiOnc #CardioOncology #Review #Guidelines
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Insurance Coverage and Pricing of Weight-Loss Drugs in the United States https://t.co/zjbdzWXtmO
@NEJM
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Retatrutide just set a new bar. 🧬 In TRIUMPH-4, Lilly’s triple agonist delivered ~28.7% body-weight loss (~71 lbs at 68 weeks) and major knee OA pain relief (WOMAC ↓ 4.5 points, 75.8%). Obesity, pain, and function being hit with one shot. The metabolic era is just getting
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2015: barely a blip. 2025: tens of millions of Rx. 📈 GLP-1/GIP agonists (Ozempic, Wegovy, Mounjaro, Zepbound) aren’t just a fad—they’re a true therapeutic revolution, finally letting us treat obesity-related metabolic disease at its biologic root instead of just patching the
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🔥Debate at #EACVI2025: Should #LGE always be quantified in Non-Ischemic #LV scar? Not so fast🚫, argument by @JccmoonMoon 📍Biology is complex, quantification oversimplifies it - #Fibrosis, #edema, #amyloid, focal vs diffuse patterns → all behave differently - #LGE is a
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🔥Debate at #EACVI2025: Should #LGE always be quantified in Non-ischemic #LV scar? Pro: Why it should always be quantified by @carlosrochitte 📍Risk rises progressively: #DCM → ↑events per 1% LV LGE #HCM → high risk (≥15%) #Ischemic → scar + gray zone predict VT/VF 📍Risk
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