Lab leak
@lab_leak
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GoF asshole who supports a dangerous young investigator #RetractProximalOrigins
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Great newsweek article covering contributions of
@TheSeeker268
@franciscodeasis
@BillyBostickson
@ydeigin
@Rossana38510044
@MonaRahalkar
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"Scientists from Wuhan and the US were planning to create new coronaviruses which did not exist in nature by combining the genetic codes of other viruses, proposals show."
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"A group of international scientists and health experts has called for the board of New York nonprofit EHA to remove Dr. Peter Daszak as president in the wake of reporting about his ties to a Chinese lab where the COVID-19 may have originated."
Nice!!
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"The world's most famous medical journal, The Lancet, sat on vital information being suppressed by China proving that the Covid virus could jump from human to human and was spreading outside of Wuhan in the early days of the pandemic."
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"A year ago I wrote in these pages that the most plausible cause of the pandemic was an accidental leak of a CoV from WIV. I have changed my view. I now think it’s likely that the cause of the pandemic is an accidental leak of an engineered CoV from WIV."
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"The Lancet letter was scientific propaganda and form of thuggery and intimidation. By labeling anyone with different views a conspiracy theorist, the Lancet letter was the worst form of bullying in full contravention of scientific method."
@JamieMetzl
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Woah!!!
BREAKING: my
@VanityFair
investigation into
@EcoHealthNYC
,
@NIAIDNews
transparency and debate over
#COVID19
origins is live. Vanity Fair obtained over 100,000 internal EcoHealth Alliance documents including meeting minutes, internal emails, reports. /1
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I can understand that the Chinese govt does not want to get to the bottom of where SARS-2 came from.. But why is there so much resistance from many Western virologists? After all, we have been reminded of the spillover potential of viruses from natural reservoirs..
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"Xi Jinping is on edge after US spy agencies somehow managed to secure a giant catalogue of genetic information from the WIV. This comes as a surprise to those in China after Beijing refused to hand over raw data earlier this year."
Only time will tell..
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"But as a longtime student of Chinese Communist political language, I will need considerable persuading that the disease came from bats or a wet market. The linguistic evidence is overwhelming that Chinese leaders believe the WIV was the source."
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"It’s not simply that the lab-leak theory was “debunked,” as news organizations repeatedly told us when anyone tried to raise it a year ago. It wasn’t even permitted to be considered."
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Daszak thanking Fauci for "helping dispel myths spun" around the virus' origins..
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"The 25-year-old visited a Milan hospital complaining of a sore throat and skin lesions in November 2019 - a month before Covid-19 would be identified in the Chinese city of Wuhan."
Why not track down possible cases at the Wuhan Military Games?
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"I think what you have seen over the last 18 months is no new evidence to suggest that this evolved from nature. Haven’t seen any evidence of it being associated with any of the animal species they’ve tested, over 80,000 animals"- Robert Redfield
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"Natural pandemics may be inevitable. Synthetic ones, constructed with full knowledge of society’s vulnerabilities, are not. Let’s not learn to make pandemics until we can reliably defend against them."
🔥🔥
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"Daszak has proven to be quite hostile toward those who wonder about whether the lab he worked with is safe, even though one would think this a perfectly reasonable question."
Fantastic article.. Pls have a read..
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The Moderna CEO is now a conspiracy theorist..
@stuartjdneil
how about another Sciam piece to cure the Moderna CEO?
Moderna CEO Stéphane Bancel:
"...escape from a lab by an accident, it's possible, humans make mistakes - so is it possible that the Wuhan lab in China was looking at virus enhancement or gene modification and then there was an accident, somebody was infected...it is possible"
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China's behavior is suspicious, no doubt, but the behaviors of some from the US virology community is even more suspicious..
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30th Jan '20: Intermediate host/sequence will likely be found within a month
31st Jan '20: 'Potentially' look engineered, inconsistent with expectations from evolutionary theory
One cannot help wondering if the dilemma that the scientists wrestled with in those sleepless nights after 1 February was more political than scientific.
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"Some 20 months after the Covid-19 pandemic first broke out, its origins remain obscure. A vigorous campaign of concealment by the Chinese authorities is the principal reason."
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"Listen, how it got to be that if it was a scientific accident, it’s conservative, and if it came from a wet market, it’s liberal, I don’t know — I’m just not sure how that got politicized" - Jon Stewart (on the origins debate)
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"A 2018 report by US diplomat Rick Switzer ... claimed the Chinese lab had “poor safety practices and no US oversight”. This was despite American taxpayers shelling out hefty sums to fund the project along with the French."
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If Kristian Andersen calls someone a conspiracy theorist, that person is most likely right/doing something right..
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"Even if it was, it’s a once in a generation fuck-up"
DUDE SERIOUSLY???!!!
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"By now, China has likely destroyed any incriminating evidence of its negligence or complicity in the worst disaster of our time. If no conclusive evidence emerges about the genesis of the pandemic, that would amount to letting China off the hook."
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"We still don’t know if a lab accident at the WIV caused COVID-19. We do know that there was a cover-up — and pvt orgs and the U.S. govt hid info/misled public regarding several key details about kinds of research that U.S. taxpayers were indirectly funding at the Wuhan labs."
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“I was threatened and ostracized because I proposed another hypothesis. I expected it from politicians. I didn’t expect it from science.” - Robert Redfield
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"The absence of the virus in samples collected from raccoon dogs and the inability of the study to establish the origin of the virus is in complete variance to the conclusions of a team led by evolutionary biologist Michael Worobey"
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Angie seems clearly irritated about the lab-leak hypothesis becoming mainstream and the push-back on the WHO report by various nations!!
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Holmes - 80% sure it came from lab
Andersen - 60% to 70% sure it came from lab
Weiss - "frightening to think it came from a lab"
How did everyone change their minds?
Scientists who authored article denying lab engineering of
#SARSCoV2
privately acknowledged possible lab origin, emails show. Via Shannon Murray of
@USRightToKnow
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"Harvard epidemiologist Marc Lipsitch said in 2017 that gain-of-function has done “almost nothing to improve our preparedness for pandemics, and yet risked creating an accidental pandemic.”"
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Linfa Wang seems uncomfortable in answering this question posed by
@Ayjchan
In a debate organized by
@ScienceMagazine
, virologist Linfa Wang is asked by
@Ayjchan
whose idea it was to insert furin cleavage sites into bat coronaviruses in a rejected DARPA proposal:
A: UNC gain of function researcher Ralph Baric
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"I think over time, the side of the ledger that says this might have come out of a lab has grown more robust and the side of the ledger that says this came out of a natural species has not really moved"
.
@ScottGottliebMD
says the origins of COVID-19 may never be known unless the intermediate host is found or a whistleblower comes forward: “This is going to be a battle of competing narratives.”
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Very good to see this
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"First of all, for a virus to jump from another animal to humans and at the same time be so well-suited to spread among humans is, statistically, exceedingly unlikely".
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From Jan-21:
Matt Pottinger: "There is a growing body of evidence that the lab is likely the most credible source of the virus."
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"You can see in all of my public statements that I have always been open to both possibilities" (translated from German)
LOL 😂😂
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"Milton Leitenberg, senior researcher at the Center for International and Security Studies at the University of Maryland, argues that SARS taught China it could ‘mislead, misinform and manipulate’ health authorities with few consequences."
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"He told the BBC that the research in both papers showed that new viruses (that did not already exist naturally) were created, and these "risked creating new potential pathogens" that were more infectious."
@R_H_Ebright
h/t
@awp1978
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"If Covid-19 was truly the result of the transmission of a virus from animal to human, surely, any responsible government would welcome urgent investigation to examine all the available evidence. But no."
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"Independently in 1978, two groups in New York City and Germany came to the same conclusion: The previous year’s flu was so genetically similar to a variant last seen in the early 1950s that it could only have started from a stored lab specimen."
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"The world's first Covid-19 patient may have been infected by a bat while working for a Wuhan lab in China, a WHO chief has admitted."
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"As we contemplate how the COVID-19 pandemic began, let’s add up all of the strange and unusual pieces of information that, in the eyes of the lab leak skeptics, are complete coincidences."
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This is truly sick:
"Close to $1.7m was spent on experiments on a total of 44 beagles, which also saw the puppies being force-fed drugs before they were killed and dissected."
Thanks to
@WhiteCoatWaste
for bringing this to light..
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A True Story
A European bat had not seen its friend in Yunnan for quite some time. The European bat booked first class tickets and travelled to Yunnan in 2019 to catch up with its buddy. Unknown to both bats, both had SARSr-CoVs.
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"Emails uncovered by US Right to Know (USRTK) - a public health research non-profit organisation - show how the director of the Wuhan Institute of Virology (WIV) told staff "not to discuss Covid-19" in January 2020."
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"A Wuhan lab that was quietly moved by Chinese officials in Dec 2019 — drawing scrutiny from a WHO scientist — operated under a mild safety level protocol where workers weren’t necessarily required to wear masks, officials said in reports." h/t
@InWuchang
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At this point, it is fairly safe to say the zoonatis are on tilt.. The emotions, PR, insults, lies, etc make it extremely extremely evident..
The LL camp hence needs to have a sensible approach and avoid getting into emotions, etc
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"Yet there is growing dismay over the inclusion of seven members of the discredited previous group, whose findings echoed the Beijing regime’s line – alongside others who have dismissed fears of a lab incident as conspiracy theory." -
@ianbirrell
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@R_H_Ebright
Why are the Democrats not so keen on this issue? I only see Richard Burr's signature in the report.. With such an approach, I doubt there would be a political reset on this topic..
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"The evidence runs to the contrary. The institute [WIV] was carrying out experiments using chimeric viruses with modified spike proteins, tested on mice with respiratory cells genetically altered to resemble those of humans."
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"The scientists who signed this letter work with dangerous viruses in labs. Their work and careers depend upon governments and taxpayers believing it is worthwhile to fund research dangerous viruses in laboratories, and that this kind of research is safe."
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"It is slightly contradictory if colleagues in China are saying that the lab leak hypothesis is unfounded in the context of China but we now need to go into laboratory investigations in other countries for leaks there." - Mike Ryan
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"The public deserves access to documents from both the Chinese govt and the (NIH). Communist China's secrecy is to be expected, of course, but the U.S. govt ought to be more transparent and stop hiding what it knows about the virus research in Wuhan."
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Which scientific evidence mounts in favor of natural origin? What is the intermediate host again?
"As the scientific evidence mounts in support of a natural origin, [American] public opinion veers in the opposite direction."
Questions: why? And is that true for the rest of the world?
#covidorigins
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".. I had biostatisticians at one of our national labs calculate the odds of this evolving in nature. And it was like one in 13 million, and ... later revised it to about one in 13 billion. ... to say this came out of zoonosis is sort of ridiculous.
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"Before this discussion, several of the world’s most influential experts believed the new virus most likely came from a laboratory – but days later, the scientists began dismissing such scenarios as ‘implausible’ and branding them conspiracy theories."
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I would like to see the evidence for the zoonosis hypothesis..
I think a lab leak hypothesis is a jolly thing but for it to be more than a hypothesis I’d like to see some evidence.
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"The anonymous WHO source suggested that if the SARS-CoV-2 virus was artificially engineered this way, it would explain why scientists have been unable to find a direct ancestor of the virus in nature."
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If it is indeed time to stop harassing scientists, zoonatis should stop harassing Alina and Richard as well..
And absolute transparency on SARS-2 origins is the need of the hour.. enough of propaganda studies with motivated reasoning
Yes, very happy & inspired by you and Prof Edward Holmes to continue advancing science to protect the world from epidemics & pandemics! So important that we keep moving forward in spite of the terrible harassment that we & other colleagues are suffering! Time to stop scientists…
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"Obviously we're very upset that we've lost funding for really for really critical work, we're going to do the work anyway, we're doing it voluntarily right now" - Peter Daszak
h/t
@AngloScot2
for this interesting segment..
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Seems EHA did not stop at SARS like viruses.. They even tweaked MERS-CoV..
h/t
@still_a_nerd
EcoHealth engaged in risky Gain-of-Function experiments in China.
“Changing the receptor binding site on MERS (from DPP4 to ACE2) is sort of crazy.”
Nunberg described the experiment as “definitely gain of function.”
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"Fauci, told a House Appropriations subcommittee that the money was funneled to the Chinese lab through the non-profit EcoHealth Alliance to fund “a modest collaboration with very respectable Chinese scientists who were world experts on coronavirus.”"
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"They told the world that the Covid-19 virus clearly couldn’t have been manipulated in the laboratory. But what they actually thought at first sight was that it had been."
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"federal grant data assembled by independent researchers shows that (EcoHealth) has received more than $123 million from the government ... and that one of its biggest funders is the DoD, funneling almost $39 million to the organization since 2013."
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"An investigation in today’s Mail on Sunday exposes how Shi Zhengli, ..., has given ambiguous, deceptive or false information on a range of subjects, from the safety and nature of their research through to her centre’s military links." By
@ianbirrell
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Wasn't the engineering part a conspiracy/crackpot theory as Andersen put it? 🤔🤔
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A sarbecovirus with an FCS emerges in a city hosting a lab which conducts research on CoVs.. And the lab in question has been known to conduct research in lower bio-safety levels..
What are the odds?
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What has systemic racism got to do with circulation of SARS-2 prior to recorded cases at the Huanan seafood market?
@jbloom_lab
Apparently we can disregard this thread because "systemic racism"... Instead it's "nOt AlWaYs BaD tO dElEtE fILeS". 🤷♂️
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“Daszak attempted to hide his close association with [China’s WIV] while he referred to anyone in the scientific community who said a lab leak should be investigated as promoting a ‘conspiracy theory’.”
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Thanks to the FOIAs, we now know that Hans, Holmes, Garry, etc believed SARS-2 was likely engineered, and that they placed high odds on LLH
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I won't be surprised if Flo and/or other zoonatis wrote threatening mails to Cold Spring Harbor
I am leaving
@BiosafetyNow
. I always knew there was some professional risk to me speaking out, but my advocacy has now become a liability that I can no longer ignore. 1/5
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"Why has China resisted the laboratory leak scenario so strongly? “It’s probably because it means that there is a human error behind such an incident, and they are not very happy to admit it,” Mr. Embarek said." - WaPo Editorial Board
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Now, this guy is a propagandist
One thing you see with these lab leak debates is casual onlookers tending to assume there is a little evidence for both sides, and that therefore it’s best to be agnostic. A relatable instinct - but it’s wrong! ALL the evidence is for a natural origin, and there’s a LOT of it.
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You and your zoonati scientist buddies should stop promoting disinformation on SARS-2 origins
Toolkit launched to help scientists deal with online abuse
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"Top Democrats and Republicans on the Senate’s Intelligence and Foreign Relations committees are pushing the Biden administration to be tougher on China as it continues its investigation into the origins of COVID-19."
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"My collaborators in Norway and I decided to look at the actual evidence and decided the references the aforementioned scientists quoted did not support their conclusions, in fact just the opposite."
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"Holmes then took a call from Kristian Andersen, a prominent virologist in California, who mentioned two features of the virus that looked suspicious. ‘This is bad,’ said Holmes; ‘I drank about three beers after that call,’ said Andersen."
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The *original* Marburg virus outbreak was the result of a lab related incident LOL
If we can believe that
#Marburg
and many other infectious diseases (e.g. Ebola, Plague, Mpox etc) is the result of zoonotic transmission why is it so hard for us to believe that it was the same with COVID-19
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1. Pushes a Huanan market origin of C19 on the basis of faulty maps and insufficient info
2. Pushes multiple market spillover hypothesis for C19
3. Promotes an FCS preprint where frequency rates of mutations are very low
When will
@MichaelWorobey
next cry wolf?
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"For months, this [lab leak] question was considered publicly taboo, prohibited from discussion ... by a group of scientists who were, incredibly, some of the same people who should have been under the most intense scrutiny."
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"It was odd for a spillover event, from animals to humans, to take off in people so immediately and spectacularly in a city with a biolab" - Jeremy Farrar
Great piece by
@ianbirrell
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My view on the origins debate as covered in Farrar's latest book..
Holmes was 80% certain SARS-2 came out of a lab while Andersen was 60%-70% certain.. Andrew and Bob were not far behind (presumably they placed a probability of 50+% on a lab leak, my guess)..
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Some actual scientists changed their minds *without* any new data!!
The most distinguishing feature of actual scientists is that they consider competing hypotheses, and change their minds with new data.
And yes, this is a subtweet.
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Yet you gave strong coverage to zoonosis although there's no evidence suggesting SARS-2 evolved zoonotically
FWIW science evolves. If strong evidence is presented in favor of bioengineering, I promise to cover it. It would be super intriguing and important. Emphasis on the evidence.
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