
Natalia Kononenko
@KononenkoLab
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RT @GattoGraziana: Our paper is finally out on our experimentally-driven neuromechanical model to explain how spinal inhibition makes you d….
cell.com
Yao et al. developed a neuromechanical model based on experimental perturbations, aligning theory-predicted with genetically labeled cell types. This work highlights the importance of inhibitory...
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RT @cell_club: Synaptophysin accelerates synaptic vesicle fusion by expanding the membrane upon neurotransmitter loading | Science Advances….
science.org
Synaptophysin allows synaptic vesicles to expand during loading with neurotransmitters, resulting in faster fusion.
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RT @AllenInstitute: How does the brain work?. Scientists are closer to the answer with the largest wiring diagram and functional map of a m….
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RT @margarida_m_p: New profile up! I had the great pleasure of interviewing @GattoGraziana on her career, passion for spinal cord circuits,….
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RT @NatMetabolism: ✨New issue!✨. Check out the latest in #metabolism research from across all disciplines. Read about #EVs, #Exercise, #Gl….
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RT @IrinaDudanova: How do different cortical neuron types contribute to circuit dysfunction in #Huntington’s disease?. Check out our new co….
biorxiv.org
Huntington’s disease (HD) is a devastating movement disorder without a current cure. Although the monogenic basis of HD is well-defined, the complex downstream effects that underlie behavioral...
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RT @CellReports: The endocytic adaptor AP-2 maintains Purkinje cell function by balancing cerebellar parallel and climbing fiber synapses h….
cell.com
Tolve et al. demonstrate that AP-2 stabilizes GRID2IP to regulate synaptic function in Purkinje cells. Loss of AP-2 disrupts synaptic connectivity, alters network activity, and impacts motor coordi...
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RT @ShorterLab: Oligodendrocyte precursor cells facilitate neuronal lysosome release:
nature.com
Nature Communications - Oligodendrocyte precursor cells (OPCs) play a multifaceted role in the brain. Here, the authors show that OPCs regulate neuronal metabolism by forming contacts with neuronal...
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We are currently hiring a motivated PhD student to study the cerebellar thalamo-cortical loop in mice and contribute to the understanding of the neuronal mechanisms of ataxia (#CRC1451). Please visit:
academics.de
University Hospital Cologne bietet Stelle als PhD position in cellular neuroscience in Köln - jetzt bewerben!
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RT @storiesofwin: Our latest profile is here! Dr. Natalia Kononenko (@KononenkoLab) studies the cellular & molecular mechanisms of neurodeg….
storiesofwin.org
studies the Cellular and Molecular Mechanisms of Neurodegenerative diseases.
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RT @GattoGraziana: Last week to apply for a PhD position in my lab to dissect the cortico-spinal circuits for hindlimb control in healthy a….
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Excited to share our latest work-#Autophagy protects Purkinje cells by keeping their glycolysis low! A novel link between brain metabolism and #neurodegeneration. Gratefull to all collaborators for making this possible! #GattoGraziana #FrezzaLab #CRC1451
nature.com
Nature Metabolism - Tutas et al. show an unconventional role for autophagy in the regulation of glycolytic flux in cerebellar Purkinje cells by maintaining the levels of the glucose transporter GLUT2.
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RT @LabPerlson: PhD position: Join Perlson Lab to explore exosomal communication at the NMJ. Use cutting-edge techniques (omics, tagging, l….
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RT @WredenbergLab: We are excited to share our latest work on mechanisms that protect from mitochondrial dysfunction. Thank you to all coll….
nature.com
Nature Communications - Finding ways to compensate for mitochondrial dysfunction is essential. Here, the authors performed a genome-wide genetic screen to identify genes that mitigate the larvae...
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RT @GGKovacsBrain: Our new review on molecular pathology of Neurodegenerative diseases .
pathologyjournal.rcpa.edu.au
Neurodegenerative diseases are a pathologically, clinically and genetically diverse group of diseases characterised by selective dysfunction, loss of synaptic connectivity and neurodegeneration, and...
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RT @MichaelOkun: What if you could target brain regions important for recovery after spinal cord injury with DBS? Can you say hypothamamus?….
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RT @EricTopol: Did we conceive the structure of neurons incorrectly all these years?.@NatureNeuro .not smooth, cyli….
science.org
Fine-grained imaging of mouse brain cells suggests “pearling” of axons that researchers think may help with signaling
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RT @LukensJohnR: Hyperactive neuronal networks facilitate tau spread in an Alzheimer's disease mouse model https://….
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RT @GattoGraziana: One PhD position open in the Gatto Lab from January 2025 to functionally dissect the input onto hindlimb premotor intern….
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