JChen Lab
@JchenLab
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Phages, bacteria, and pathogenicity islands. @NUSMedicine.
Singapore
Joined October 2018
Our latest! Phages no longer own transduction! Staph pathogenicity islands engage in lateral transduction and can also piggyback LT to drive genome hypermobility. Amazing work by @melchee92 @DrEsterSerrano @rbacigalupe @jrpenades @jrossfitz and others!
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RT @TaniaWong88: Pleased to share our latest study @NatureComms. We show that the host metabolites fumarate and itaconate impose selective….
nature.com
Nature Communications - This study reveals how the pathogen Staphylococcus aureus adapts to the lung microenvironment, rich in host metabolites fumarate and itaconate, by using a key enzyme, FumC,...
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RT @FdlC61: A new encyclopedic review, for plasmid lovers:..We (Mapi, Eduardo and I) hope you like it!.
academic.oup.com
Abstract. Plasmids play key roles in the spreading of many traits, ranging from antibiotic resistance to varied secondary metabolism, from virulence to mut
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RT @TorresVJ_Lab: 1/11 New #MRSA #Staph publication from Dr. Diane Boff a talented former postdoc co-mentored by the @TorresVJ_Lab and @DrS….
science.org
A natural rodent model of Staphylococcus aureus infection unearthed LukMF′ as a driver of skin and soft tissue infections.
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RT @AnatHerskovits: Happy to share our new preprint describing prophage encoded anti-phage defense system,TERi, that targets the terminase….
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RT @jrpenades: New mechanism of gene transfer! With @CostaT_Lab @CBRB_Imperial, cf-PICIs form tail-less elements that, once released, sprea….
biorxiv.org
Some mobile genetic elements spread among unrelated bacterial species through unknown mechanisms. Recently, we discovered that identical capsid-forming phage-inducible chromosomal islands (cf-PICIs),...
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RT @Yuanqiao1002: We have a fully funded PhD scholarship for Aug 2025 intake. If you are interested in joining our research group, please….
ntu.edu.sg
A rigorous PhD programme in Chemistry combining advanced coursework with research experience.
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RT @milja001: PhD projects at University of Leicester .Including three phage projects . With @MarthaClokie , and me. Including an iCASE….
le.ac.uk
The Midlands Integrative Biosciences (Doctoral) Training Partnership (MIBTP) is a BBSRC funded doctoral training partnership between University of Warwick, University of Birmingham, University of...
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RT @GeiselBiofilm: Pls share: Microbiology faculty position available at Texas A&M University.
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RT @AnatHerskovits: Our paper is finally out at Nature Microbiology. A team effort discovering Tailocin cell factories. Listeria monocytoge….
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RT @TorresVJ_Lab: 1/7 Happy to share a new publication from the team spearheaded by @Keenan__Lacey published today in @ScienceAdvances. Thi….
science.org
Dietary and water restriction increases susceptibility to antimicrobial resistant pathogens by disrupting macrophage function.
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RT @FillouxLab: Our T6SS paper on TssA is now available @NatureComms .A publication marathon but so happy to see this accepted on my birthd….
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RT @antonia_sagona: Thank you to our excellent reviewers and Editor for helping us to improve significantly this review with their very use….
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RT @jakob_tr: Just missing April fool's, here is something that is no laughing matter:.In @NatureMicrobiol, we des….
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RT @jrpenades: Led by @jakob_tr and @quiles_nuria, with @lasa_lab, we show that prophages utilise noncontiguous operons to balance immuni….
nature.com
Nature Microbiology - Prophage-encoded anti-phage defence systems in Staphylococcus aureus protect hosts from superinfection but also prevent autoimmunity via an overlapping gene.
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RT @KimInGeneva: PhD student opening! We are collaborating with the team of David Johnson @EawagResearch to understand E. faecalis polymic….
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RT @CorneliusLeeYH: Here's a little venture of mine🚀!. We've launched Scientifica Media, a scientific communication company that helps conn….
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RT @YHGanLab: Here's our latest endeavour into #AI-driven identification of synergistic drug combinations (out of half a million possible o….
advanced.onlinelibrary.wiley.com
Twelve drugs at three concentrations generate 531 441 combinations. The IDentif.AI harnesses the in vitro efficacy data of 155 OACD-designed combinations to rank and predict synergy in all combinat...
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RT @yunnhwen: A great group effort in identifying broad spectrum,new drug combinations against #MDR bacteria using #AI platform! https://t.….
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