Glofi+R-CHOP/R-polaCHP. I really like this study schema, allowed for short Dx to Tx interval to actually get a high risk group in study. #lymsm #ASH24

CART could have it ALL. Obe-cel results @NEJM: 👉127 pts 👉complete remission 55% 👉median event-free survival 12 months 👉1-year survival 65% 👉severe CRS/ICANS in 2% and 7% 👉survival curve plateau but limited follow-up 👉high tumor burden still a challenge Congrats

Bridging RT v systemic tx retrospective before axi-cel #ASH24: - 98 pts, 35 RT bridging alone - CR 85% RT, 71% chemo (not significant) - 1-yr PFS 75% RT, 49% chemo (significant) - MV model PFS: improved PFS (HR 0.41) with RT alone Time for a randomized trial. #lymsm

7:30: Declare big day of writing 8:00-17:00: Fail to write 17:30: Declare big day of writing tomorrow

Gonna get a tattoo on my chest that reads "just because a result is statistically significant does not mean it is biologically significant" & a matching tattoo on my back that reads "just because a result is biologically significant does not mean it is statistically significant"

Focal deletions of noncoding regions in cancer genomes can have unexpected consequences. Out now in @BloodJournal, we’ve discovered an intriguing mechanism of oncogene activation whereby focal deletion of a ‘promoter tether’ leads to aberrant expression of IRX3 in T-ALL. Thread👇

Dr Jamie Kuzich (@JantonKay) from @TheDawsonLab has received the @ASH_hematology 2024 Global #Research Award - one of just of 11 awarded to early career investigators from around the globe. Watch 👇Read more: https://t.co/G8cPJpJgIk #bloodcancer #hematology #haematology

Last month, the Dawson Lab celebrated our 10th year in action! 🎉 It was a wonderful day of laughs, catching up, and reflecting on just how far we’ve come over the last decade. What a great looking group! See ya in 5 years! 🥂

https://t.co/4SPB0Ey6aW

So good to finally see this out in all its glory. I remember @charles_bell92 first telling me about this system on the drive down to lab retreat in my first few weeks in the lab, and it was beautiful to see the story develop. Bravo, Charlie!

Proud to see our paper describing BARtab and bartools, two integrated software tools for the analysis of synthetic cellular barcodes is now published @CellRepMethods! We hope the community finds this work useful. https://t.co/hoTc4bw38S

Our latest paper from ⁦@TheDawsonLab⁩ - huge congratulations to ⁦@HenriettaHolze⁩ & ⁦@DaneVass⁩ who led this work - hope the lineage tracing / barcoding community find this helpful

How to pick a problem. Today in @CellCellPress. 1/53 https://t.co/Id4YaXWuup

When the results you've been excited about for 2 years turn out to be an artifact

Stellar 2024 Lab retreat with the best people! Ready for the year ahead! ⭐️ #DawsonOpen🎾 #unitedinnovation #boundlessdiscovery #bigimpact

What a PERFFect day to share our new preprint! With @tsion_abay #BobStickels @MerilTakizawa @ChaligneRonan and @Satpathology, we introduce PERFF-seq, a new experimental approach to studying rare cells with scRNA-seq via transcript-specific enrichment. https://t.co/woKvdEdOf0 1/n

me on my way to annoy my lab mates instead of writing this abstract

@arjunrajlab Reminds me of what Brenner said about differentiation in Loose Ends (@CurrentBiology). https://t.co/xekW87NY4d

We’re hiring 2x bioinformatics/computational biology RA’s in @MAF_Dawson’s lab in Melbourne! You’ll be working on all things single-cell and harnessing the power of our SPLINTR lineage tracing tool! https://t.co/UZzlRRdraB Please share with your network☺️

Excited to share my PhD story, out in @Dev_Cell today: https://t.co/2yyyL0mHH9! We show that Nrf2-driven induction of the pentose phosphate pathway stimulates liver regeneration after injury. Thanks to @DrAndrewCox, @MAF_Dawson, Cox Lab and @TheDawsonLab members! Incoming 🧵1/9