Coming up at #ESMO25: MSK’s Dr. Helena Yu (@HelenaYu923) will discuss results from a phase 1 global study of Iza-Bren (BL-B01D1), an EGFR x HER3 bispecific antibody-drug conjugate (ADC), in patients with metastatic or unresectable #NSCLC and other solid tumors. @myESMO Learn

I am thrilled to receive the @NIHDirector’s New Innovator DP2 Award! With this $2.5 million in funding, we will turn off every kinase in the human genome and accelerate breast cancer drug discovery. Join us, we are recruiting at https://t.co/DY2BtorbC4! @NIH_CommonFund @theNCI

Life is too short to worry about stupid things. Have fun. Fall in love. Regret nothing, and don't let people bring you down. Study, think, create, and grow. Teach yourself and teach others. 🧠

What is the risk conferred by my disease? One of the hardest questions to answer in medicine. A on the development of the International Prognostic Scoring System Molecular in MDS published today

We woke up today to a new era in breast cancer treatment. I have never been more proud or grateful to be part of a transformative moment in cancer research. Most importantly, I look forward to seeing the new hope this brings for patients with cancer. #ASCO22

Little girl singing "Let it go" in a shelter #UkraineRussianWar #Ukraine #UkraineUnderAttack

Video of Ukrainian father saying goodbye to his kids while he stays behind to fight. Fuck war.

If you needed more proof in https://t.co/gOl6QNfYjN by @MitchKSmith (during Delta wave)

This is absolutely beautiful 😻 https://t.co/zdm5w0KqrX

Hospitalizations are increasing as Omicron cases reach record highs in NYC and all across the country. But as I noticed on my recent ER shifts, take a look at who needs admission to the hospital for severe Covid? 👇 TL;DR It’s the unvaccinated.

Thanks my mentor Howard Scher, co-authors and PCF YIA funding from @PCFnews @soulehoward1. Took a few years but finally my first clinical study is out! The Effect of Corticosteroids on Prostate Cancer Outcome Following Treatment with Enzalutamide.

The vaccination rates in states with mandates vs those without (it isn't just the mandates, but the difference is striking) by @nytgraphics @billmarshnyt @albertsun

Pretty, pretty good timing for a cover on the Paxlovid pill @ScienceMagazine

The T cell response to mRNA vaccination is extraordinarily robust & durable, especially as determined by draining lymph nodes. That's what helping to prevent severe disease, irrespective of variants (including Omicron) https://t.co/xgHbRI1ZDs @TheBcellArtist @WUSTLmed

Just published @Nature Why do children usually have a mild Covid course? A comprehensive assessment of innate and adaptive immunity, blood and airway epithelium. in kids and adults, shows there are multiple explanations https://t.co/M6iBoZZjtc

Omicron resulting in less severe illness The latest roundup of data from this preprint with South Africa data and from Denmark https://t.co/sdJUz5w6vU by @mroliverbarnes @jburnmurdoch @rmilneNordic 1. Less hospital admission in South Africa

You know it's a good day in the pandemic when: —The 1st anti-Covid pill is cleared —More indications that Omicron is associated with less severe illness and tends to come down from its big surge as quickly as it ascends —The 1st pan-coronavirus vaccine is ready for Phase 2 trials

Another superb @SubstackInc review by @EricTopol; this on Paxlovid, Pfizer's new oral antiviral. Given its preserved efficacy vs. Omicron & fact that it's likely to ⬇infectivity as well as severe illness, it's crucial to expedite approval & distribution. https://t.co/GDzVzLiiMF

Davide Corti has some very interesting data for neutralization drop against Omicron that includes Sputnik V and SinoPharm (BBIBP-CorV, inactivated vaccine). https://t.co/D7gwmVaRd1

Omicron replicates much better than Delta in bronchus, but not in lung, explaning why Omicron is so transmissible. Excellent ex vivo studies from Michael Chan @HKU_SPH and John Nicholls in Department of Pathology @hkumed