Thiagarajah Lab
@JRTlab
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Thiagarajah Lab Twitter @bostonchildrens, @harvardmed ac
Boston, MA
Joined February 2021
Also Michael’s paper on an optimized end-to-end system and method for multiplex immunofluorescence imaging - check it out :
nature.com
Communications Biology - A fast, automated, high-resolution, low-cost multiplex immunofluorescence method to understand spatial organization of tissue.
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A few lab updates: Our major consortium paper on the genetics of Congenital Diarrheas and Enteropathies came out last month. A major collab between BCH, SickKids (@AleixoMMuise), UCLA (Martin Martin) and Vanderbilt (@GoldenringLab )
pmc.ncbi.nlm.nih.gov
Next-generation sequencing (NGS) has enabled precision therapeutic approaches that have improved the lives of children with rare diseases. Congenital diarrhea and enteropathies (CODE) have high...
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RT @snaqvi1990: We are recruiting postdoctoral fellows! . Interested in using quantitative tools to study gene regulation in stem cell-deri….
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RT @XuZhouLab: Super thrilled to share a preprint from the lab We found pH regulates the inflammatory response 🔥in….
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RT @JCellBiol: Modeling the cell biology of monogenetic intestinal epithelial disorders. New Review from Izumi Kaji (@iKajiLab), Jay Thiaga….
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RT @KeYuan_BCH: New postdoc opening in my lab in vascular remodeling studies. We do cool science. Email if interested. @atscommunity @atsea….
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RT @Synth_Immune: Pleasant tidings that our paper's recognized as one of @CellReports Best of 2023. Special congrats to @pascal_devant, @E….
cell.com
Devant et al. investigate the actions of reactive oxygen species on the pore-forming protein GSDMD. They show that oxidation of a specific cysteine in GSDMD (C192) promotes its oligomerization,...
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Our paper on Microvillus Inclusion Disease and using patient derives enteroids is out! A pan lab effort and great collaboration with @iKajiLab and @GoldenringLab. #organoids @harvardmed.
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RT @jclinicalinvest: #Cover: Patient-derived enteroids for microvillus inclusion disease: . The cover image shows a….
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Congratulations to Kate in the lab for receiving the FASEB Early Career Investigator award at the #GESRC. 💪 work!!. @katebugdagwilt.
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Great finish to a fun day of meeting, brainstorming and science with the Gut-AGE team! @SyedLabGI_AI @ordovas_phd @DrJSilvester
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Don't miss @katebugdagwilt's talk in this morning's session #GESRC.
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Postdoc @katebugdagwilt presenting at a local career fair teaching about her organoid work #ScienceInAction #WomenInSTEM #scienceoutreach
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RT @CellReports: Interleukin-23 receptor signaling impairs the stability and function of colonic regulatory T cells
cell.com
Jacobse et al. show the cytokine interleukin-23 specifically negatively regulates suppressive function and survival of intestinal regulatory T cells in mice.
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Another example of the importance of redox at membranes! Great collab with @pascal_devant @Synth_Immune @HafnerIva @jkagan1 and more. Great work by @ElsyNgwa on the redox biochemistry! See Pascal’s nice tweetorial!.
ROS oxidize a specific cysteine in the N-terminus of GSDMD to promote its pore-forming activity!.Read more in our new paper, out today @CellReports. A thread:. @harvardmed @BostonChildrens @VirologyHarvard @HarvardMicro @DanaFarber .
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RT @pascal_devant: ROS oxidize a specific cysteine in the N-terminus of GSDMD to promote its pore-forming activity!.Read more in our new pa….
cell.com
Devant et al. investigate the actions of reactive oxygen species on the pore-forming protein GSDMD. They show that oxidation of a specific cysteine in GSDMD (C192) promotes its oligomerization,...
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Happy to share our latest review in congenital diarrheas and enteropathies- check it out here Thanks to Stephen and David for their help pulling this together!!.
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RT @XuZhouLab: Our division has a search for junior faculty across all biology science disciplines @harvardmed @BostonChildrens We are look….
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