Happy to share our latest work by @YYexin et al. on antibody-mediated control of endogenous retroviruses in mice. In the process, we found “natural antibodies” with broad reactivity against enveloped viruses. Here is how “panviral” antibodies work 🧵(1/) https://t.co/kU8NBK5KF9

This incredible discovery of natural antibody recognition of viral gycans by @YYexin is the result of her meticulousness, creativity, and perseverance. So satisfying and inspiring to watch this story unfold and take so many unexpected turns during my PhD. Congratulations to all!!

Absolutely fantastic thesis defense being delivered by soon to be doctor @tianyangmao, spanning RIG-I antiviral approaches to #PrimeandSpike nasal vaccines 🤩 @YaleIBIO @YaleMed

In this study, @MiyuMoriyama et al investigate how well SARS-CoV-2 variants of concern (VOC) suppress MHC I needed for recognition by cytotoxic T cells. This question is important to understand how well the virus limits CD8 killing 🧵(1/) @biorxivpreprint https://t.co/TLvnB7NotN

Our new study by @JieunOh9 @ericsongg @MiyuMoriyama et al shows that immune priming via intranasal route provides superior protection against heterologous respiratory virus challenge. The key is in inducing local secretory IgA with broader coverage. (1/) https://t.co/2RgDVMGvqh

Today is #WorldAidsDay2021 Sharing our new review on "Impact of Chronic HIV Infection on SARS-CoV-2 Infection, COVID-19 Disease and Vaccines” by @YYexin. A short thread (1/) https://t.co/Ud4EKiCVS9

HELLO, world! Excited to share our work online today @CellCellPress with @Joshilabyale and Dr. Joe Craft. Grateful to all the collaborators that made this study possible!

Thinking of all the women left anxious and confused about the vaccine, who deserve so much more from us. And eternally grateful to the two women in particular @randihepstein and @VirusesImmunity who believed in this message and in me. Mentorship matters. https://t.co/E4uWPimLEf

And we’re off to a fantastic start to the #IwasakiLabReunion Symposium! In the first session @EllenFoxman discussing viral interference during respiratory infections and @JennyLund15 on the role of Tregs during viral infections. 🙌🔥

AND IT’S LIVE: our latest pre-print, on the use of saliva as a diagnostic sample for #SARSCoV2 testing, from the massive team effort on Yale’s #COVID19 response @YaleSPH @YaleEMD @YaleMed @VirusesImmunity @YaleGH @Yale @YNHH

New Comment article from @VirusesImmunity and Yexin Yang on the potential danger of suboptimal antibody responses in COVID-19

This is a cautionary tale of how anti-Spike antibody may make COVID disease worse. In this study, the authors show that anti-Spike IgG made SARS-CoV disease worse by switching macrophage from wound-healing to proinflammatory phenotype. A thread (1/n) https://t.co/T8ipHt5tRH

Let's dispel the notion that "novel coronavirus is just like the flu". Sharing this striking comparison of #Flu, #COVID19, #SARS and #MERS made by @BioRender. #COVID19 is 30x more deadly and almost 2x more contagious than the flu. We have no existing immunity to COVID19.

Researchers rush to test #coronavirus vaccine in people without knowing how well it works in animals. A great summary and discussion by @EricBoodman 👇🏽 #COVID19 #Vaccines #Immunology https://t.co/YfGjRasiva via @statnews

New #SARSCoV2 #COVID19 paper just accepted at Cell! Cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically-proven protease inhibitor. #2019nCoV

The first @VirusesImmunity lab brain tumor paper is out today! https://t.co/Dm7eqglEP9. We began the project wanting to understand the role of meningeal lymphatics in brain tumor. To our surprise, when we expanded the lymphatics with VEGF-C, mice could no longer grow tumors!

Meet the @VirusesImmunity lab from @YaleIBIO @YaleMed They're interested in Cellular trafficking; Host-pathogen interactions; Immune memory; Innate immunity; Mucosal immunology; #Neuroimmunology; #Vaccines; Viral immunity #ImmunityCommunity https://t.co/9nuHDInmXt

Sci-art is always a lot of fun!

So grateful to find out about my student giving a great talk through Twitter! Of course I am not at all surprised - @ericsongg is a rock star! #GRC_neuroimmune. @YaleIBIO

Just one week until the Yale iBio graduate student symposium. An amazing lineup of speakers.