Following a decision by @ICR_London we will no longer be posting on Twitter. You can now find us on @bluesky .

@MyMKaiser @decodegenetics @ERC_Research @Vetenskapsradet @MyelomaUK @CRUKresearch @The_MRC @UKRI_News @threadreaderapp unroll.

We are now on @bluesky !.

Further evidence of the massive disparity in the Fortnum&Mason pies. They were the mini ones that had a crunchy top, which apparently some took issue with!. Wishing everyone the best over the festive season! 🎄

And the winner . is Morrisons, by a hair! Followed closely by Fortnum&Mason and Greggs. Bars in the middle represent the median scores, and the mincepie icons are the mean. F&M was very divisive, whereas Greggs had the lowest variance!

It's that time of the year again - the annual Houlston Lab #mincepie taste test!

RT @Bradleyomics: Delighted to share the bulk of my PhD has just been published in @Gut_BMJ! (. In this multidiscip….

Massive congratulations to team members Jay, Phil, Sam and Molly on completing the @RoyalParksHalf marathon yesterday with some spectacular times, raising money for our #CancerResearch at @ICR_London. If you'd like to support:. #RoyalParksHalf #fundraising

A couple of our team members are taking part in @RoyalParksHalf on Sunday. Good luck to everyone taking part!.

RT @ICR_London: Happy #AdaLovelace Day! 🖥️ . Ada Lovelace is known for being the first computer programmer and paved the way for #WomenInST….

Happy #AdaLovelace Day! Listen to Houlston team member, Jessie @jessicamhislop, talk about the importance of #WomenInSTEM.

RT @NatureRevGenet: Genome-wide association testing beyond SNPs #Review by Laura Harris, Ellen McDonagh, @xiaolei_g….

RT @SantiagoThibaud: 🚨 New paper🚨 in @BCD_AACR! Thrilled to announce our study: MM Risk & Outcomes Associated with Pathogenic Germline Vari….

Celebratory chromatin cake 🎂

Many thanks to all the participants in the study, our collaborators (Malcolm Dunlop and Bradley Harris at @EdinburghUni Cancer Research Centre), and @CRUKresearch, @wellcometrust, and @The_MRC (@UKRI_News) for funding. /end.

Our analysis provides an outline for a generalised strategy to profile disease-associated GWAS loci using high-throughput variant screening in concert with multilayered functional annotation.15/.

In summary, we provide insight into the functional basis of risk loci, implicating novel genes in the development of CRC, expanding the potential for therapeutic targeting.14/.

This integrated analysis identified 208 genes from the GWAS loci with a direct link between risk variant and gene. Through literature mining we find most of the genes (142/208) have no documented role in CRC, and 47 of these presently have no established role in any cancer.13/

Additionally, we applied the activity-by-contact (ABC) model to systematically link Micro-C data in conjunction with ATAC-seq, H3K27ac ChIP–seq and RNA-seq data. Loci were linked to a gene if there were at least two sources of evidence (SMR normal, SMR tumour, ABC, Micro-C).12/.