Gregg Fonarow MD
@gcfmd
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How many clinicians believe having 4 Class 1 guideline-recommended, disease modifying, ☠️⬇️ medical therapies for HFrEF means:. Start 1 or 2 of these therapies and then wait for months/years or till the patient has a HF 🏨 or CV ☠️ before considering starting the other 💊
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HFrEF. Q-GDMT (ARNI+BB+MRA+SGLT2i). 🛟 Extend median overall survival by 7-11 YEARS. Self-pay cash price all 4 💊. $121 per month. 🎰 Incredible value . ✅ Available now. What is your diagnosis to Q-GDMT time? ⏱️
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Comparison of Fixed vs Age-Adjusted NT-proBNP Cutoffs to Define Pre–Heart Failure . JACC @JACCJournals @BiykemB
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What updated thresholds for statin use could mean for patients via @statnews. @JAMACardio @HeartDocSadiya.
statnews.com
A new heart risk model had raised questions about who should take statins. A new study to "right-size" yields a similar answer to the old model.
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“steroidal MRAs have little to no effect on CV mortality in patients requiring dialysis”. Safety and efficacy of steroidal MRAs in patients with kidney failure requiring dialysis: a systematic review and meta-analysis of RCTs - The Lancet
thelancet.com
Our findings suggest that steroidal mineralocorticoid receptor antagonists have little to no effect on cardiovascular mortality in patients requiring dialysis. There is insufficient information on...
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RT @GiuseppeGalati_: 🔥 #HeartFailure attributed mortality in Europe, 2012–2021. Growing numbers of an epidemic that is now even more deadly….
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It has proved to be so very difficult to improve CV outcomes in patients receiving maintenance dialysis. Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE) - The Lancet @JavedButler1 @mvaduganathan @AndrewJSauer.
thelancet.com
Among patients receiving maintenance dialysis, spironolactone 25 mg daily orally did not reduce the composite outcome of cardiovascular mortality and hospitalisation due to heart failure compared...
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During the time period that so many effective therapies became available which could prevent incident HF and improve outcomes in prevalent HF…. Why in the US did age-adjusted HF related mortality go up?. Why in European countries did age adjusted HF mortality go up?
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Worldwide red alert🚨. HF attributed ☠️ ⤴️⤴️⤴️. Critical to prioritize prevention and improved treatment of HF globally . Effective evidence-based strategies/therapies exist and are guideline recommended, yet massive implementation gaps, variations, and disparities.
Heart failure-attributed mortality in Europe, 2012–2021. Heart failure-attributed mortality in Europe increased between 2012 and 2021. Substantial disparities persist across European regions and countries. @mvaduganathan @gcfmd @SJGreene_md @AndrewJSauer @ankeetbhatt @BiykemB
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RT @CircHF: Simultaneous or Rapid Sequence Optimization of Medical Therapy for Heart Failure: Time to Keep Score @GCFMD @SJGreene_md #AHAJo….
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RT @SS_cardiol: Excited to share our editorial, guided by @SJGreene_md & @gcfmd, now out in @CircHF!. A shift in focus for GDMT: It's not j….
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RT @SJGreene_md: 🏆Simultaneous or Rapid Sequence Initiation of Combination GDMT . GDMT scores to date capture important omissions & underdo….
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RT @JAMANetworkOpen: #GLP1 receptor agonist use for patients with type 2 #diabetes was associated with a slightly higher risk of developing….
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RT @drbennisahmed: Optimizing Medical Therapy Using Remote Monitoring and Artificial Intelligence in Patients With Heart Failure: The TURIN….
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RT @ankeetbhatt: Does timing of #GDMTworks affect economic value? In @JCardFail from #DELIVER, we examine #CostEffectiveness of #SGLT2i by….
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RT @MushoodCh: Our new publication in.@RPTHjournal !.🩸 Reduced-dose DOACs for extended #VTE treatment.⚖️ Similar efficacy to full-dose.🛡️ L….
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RT @drbennisahmed: Optimizing Medical Therapy Using Remote Monitoring and Artificial Intelligence in Patients With Heart Failure: The TURIN….
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RT @JTThibs: This is SO COOL! New in @JACCJournals #JACCHF: HF-AI software system that integrates HF guidelines & pt info improved GDMT usa….
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