Federico Pietrocola
@FedericoPietr12
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Group Leader at Karolinska Institute- Department of Cell and Molecular Biology
Stoccolma, Svezia
Joined November 2019
‼️🚨Preprint 🚨‼️ Check out our recent work driven by brilliant @JeromeSalignon and @LabRiedel with great support from @martsiokou, @Pmarques_G. Extensive 🧵 below ⬇️ ⬇️ @Vetenskapsradet @impetusgrants @WellcomeLeap @Cancerfonden @karolinskainst @WennerGrenOrg
📦 Pasta R package + tutorials → https://t.co/9HtbpaxBKH • Preprint https://t.co/YWzuKdAFyP • Feedback welcome! 🙏 Cooked with 💙 by @FedericoPietr12 @LabRiedel @Pmarques_G @martsiokou, at @karolinskainst @Stockholm_Uni #Bioinformatics #Longevity
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Hard to believe it’s already been a week since Iryna’s brilliant PhD defense! 🌟 Her presentation left a lasting impression! congratulations Dr. Moskalevska on an outstanding achievement! 👏 #PhDDefense #ProudPI
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📢 We organize a Workshop “Senescence Immune Surveillance: Implications in Cancer and Aging” 🗓 October 22, 2025 – Le Galet Auditorium, Pasteur Hospital Leading experts (Institut Pasteur, Weizmann Institute, Karolinska Institutet…) and Free entry! Don’t miss it!
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We will be there, will you? Register now:
🌍Join the the conversation shaping the future of aging research! Meet world-leading scientists at SENESCEL 2025 — the Conference on Cellular Senescence in Health & Disease. 📅 Nov 6–7, 2025 📍 PRBB, Barcelona Seats are limited — secure your spot today: https://t.co/Vd5ZegFsAt
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Nature research paper: Reprogramming neuroblastoma by diet-enhanced polyamine depletion https://t.co/hvdGzzAlKZ
nature.com
Nature - Enhanced polyamine depletion in neuroblastoma models decreases translation of mRNA codons with adenosine in the third position, reprogramming the tumour proteome away from cell cycle...
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New @NatureGenet review from our NIH SenNet @sennetresearch OMICS WG co-led by @shenglilab We share practical considerations for identifying, characterizing & spatially mapping #CellularSenescence, plus computational #multiomics insights!!
nature.com
Nature Genetics - This Review discusses multiomic approaches for the characterization and biological understanding of cellular senescence, including detailed case studies on skeletal muscle and...
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Now >200 papers/preprints on (diseases of) aging/relevant tools citing support from @impetusgrants 📈
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1/11 Our study on subclonal immune evasion in non-small cell lung cancer has just been published in @Cancer_Cell
cell.com
Dijkstra et al. investigate whether individual cancer subclones differ in their immune evasion capacity. They establish organoids representing distinct subclones from multi-region lung cancer...
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Two months after ARDD another stellar meeting is taking place. Please consider traveling to Iceland for the Nordic Aging Society annual meeting. It will be a blast! Register yourself for the society at https://t.co/LPREaa6hIl and get free entry!
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Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress https://t.co/PIm9Lu0MyC
nature.com
Nature Neuroscience - Rhine et al. find that neuronal aging leads to widespread dysregulation of RNA biology, including mislocalization of splicing proteins like TDP-43, chronic cellular stress and...
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Now online! Senescence-resistant human mesenchymal progenitor cells counter aging in primates
cell.com
Genetically engineered senescence-resistant human mesenchymal progenitor cells can reduce aging markers and improve tissue and cognitive functions in aged macaques, highlighting their potential as a...
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Pasta, an age-shift transcriptomic clock, maps the chemical and genetic determinants of aging and rejuvenation https://t.co/6lXcNrTwpz
biorxiv.org
As the prevalence of age-related diseases rises, understanding and modulating the aging process is becoming a priority. Transcriptomic aging clocks (TACs) hold great promise for this endeavor, yet...
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Newly developed, open-source aging clock 🕰️ helps identify rejuvenating drugs 💊and gene perturbations 🧬with potential application in regenerative medicine and longevity therapies. https://t.co/mseNwlue31
lifespan.io
Scientists have developed a new open source transcriptomic aging clock and published their work as a pre-print [1]. The newly identified rejuvenating drugs and gene perturbations could be […]
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📦 Pasta R package + tutorials → https://t.co/9HtbpaxBKH • Preprint https://t.co/YWzuKdAFyP • Feedback welcome! 🙏 Cooked with 💙 by @FedericoPietr12 @LabRiedel @Pmarques_G @martsiokou, at @karolinskainst @Stockholm_Uni #Bioinformatics #Longevity
github.com
P̲redicting a̲ge-s̲hift from t̲ranscriptomic a̲nalyses - jsalignon/pasta
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After the successful #yICSAAmsterdam event, we are back with the @YicsaC conference in Stockholm
🚨 Registration deadline extended to March 25th 🚨 We have decided to extend the registration deadline for our upcoming @YicsaC conference at KI on May 6th & 7th, 2025. Registration link here: https://t.co/JqAGgMBpxB Looking forward to seeing you there!
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Delighted to see our upcoming conference at KI in Stockholm has been announced. Register for free below (deadline March 11th).
📣 Join us in Sweden 🇸🇪! Next yICSA symposium will be taking place on Tuesday, May 6th and May 7th, at Biomedicum, Karolinska Institutet. Keynote speakers: @SpaldingLab & @mcollado_CIMUS Register: https://t.co/by5VTJlPT3‼️
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Quantifying metabolites using structure-switching aptamers coupled to DNA sequencing https://t.co/wARKBy0Lvq
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