Postdoc | VHIO, Barcelona Immunotherapies succeed in only ~20% of cases. Help us break resistance by engineering the right environment. Join the Aging & Cancer Lab 🌍 👉Apply: https://t.co/jprHnMMt8h | https://t.co/ExiKaXfa0x

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Ready to start the 2nd International @SENESCEL meeting! 2 days of top ageing science in Barcelona at @the_prbb.

Two years ago, Francesca, Ning, and Marc began their PhDs full of excitement — and a touch of worry. Now they stand at the edge of the Valley of Despair. Over tacos and nachos, we toasted our fallen hypotheses. With no emotions left hidden, we’re ready to cross the desert.

🐁Naked mole rats live up to 16× longer than mice, and a new Science study hints their secret may lie in how they sense DNA damage via the cGAS protein. Will we one day inject naked mole rat cGAS to live longer? To be seen… 👀 #JournalClub 🔗

A year ago, Adelina applied to our lab through the VIDA call — a stellar Medical Oncologist with no bench experience. As a small lab, we had to say no. The next day she came back with an idea: apply for the ESMO Fellowship (deadline in 3 days!). Yesterday she received her award.

Childhood cancer survivors often develop age-related diseases early. 🧬A new St. Jude Lifetime cohort study finds epigenetic age acceleration explains <30% of this variance — hinting that key drivers of therapy-induced aging remain unknown. #JournalClub 🔗

📚Culture dishes and in vivo studies are not our only experiments. As our lab turns soon 3, we keep on testing how to grow a culture where ideas and people thrive. For anyone curious about the science of teamwork, The Culture Code is a brilliant field guide. 📚 #LabReads

It was an absolute honor to host Jan Hoeijmakers — a true legend in the Aging & Cancer field! 🔬 His groundbreaking work linking DNA damage repair to aging and cancer has shaped decades of research and continues to inspire us at the Aging and Cancer Lab. 💡

🥳🎖️🎊 Congratulations to Francesca from the Aging & Cancer Lab for winning the Best Participant Talk Award at the @CancerCoreEU Summer School in Translational Cancer Research 2025! Thank you for your great work and bravo, Francesca! 👏

📰By integrating single-cell RNA sequencing datasets, Cong et al. characterize the evolution and interactome of hematopoietic niche from embryonic development to aging. #JournalClub https://t.co/8Pli0k0wni

Lung cancer reprograms the bone marrow to its advantage. Hedge et al. (@MiriamMerad lab) show that tumors trigger an NRF2-driven stress response in myeloid precursors, which then suppress anti-tumor immunity. Blocking NRF2 boosts immunotherapy. #JC 🔗

💬 On the second day of #CCESumSchool25, @MateMaus delivered a lecture titled “Age-related metabolic bottlenecks and cancer promotion.” #CancerResearch

📣 New VHIO – @CaixaResearch Scientific Seminars @FundlaCaixa❗️ 👨‍🔬 Jan H.J. Hoeijmakers 🔹 DNA damage and transcription stress and the unexpected impact of nutrition on aging, cancer and medicine in general  🗓 10 October, 12 PM  👨‍🔬 Host @MateMaus Register at 👉

🔬 Day 3 #CCESumSchool25 Francesca Cogo presented “Therapy-induced and age-related iron dysregulation as a driver of cardiac aging in childhood cancer survivors”, & @smartinlluesma delivered the lecture “Reviving TIL-ACT: Rediscovering an effective melanoma treatment after more

🚀 Yesterday, we welcomed Miriam Sanso from @idisbaib as an invited speaker in our @maus_lab Seminar Series. Miriam shared striking findings on how pregnancy shapes breast cancer therapy responses—an inspiring and thought-provoking talk!

We will be there, will you? Register now:

Summer Internship at the Aging & Cancer Lab | Aiste’s Story🌱🔬 Hear from Aistė Avižaitė, who joined us from Lithuania’s @VU_LT to explore aging & cancer and grow in translational oncology at @VHIO. ▶️ https://t.co/uv0VYcJWBq

📰 In aging bone marrow, cancerous clones thrive by adapting through mutations. Kang et al. show that giving immune cells the same mutations tilts the balance back—helping them resist exhaustion and fight cancer in this hostile niche. #JournalClub 🔗

📰Aging disrupts metabolic supply chains, constraining cell renewal. But how do we detect these shortages? In >5000 patients, Tapio et al. show that low ferritin is the best predictor for bone marrow iron. A study with broad implications. #JournalClub 🔗 https://t.co/TrOwGuKp4P