
Eric Lenze MD
@EricLenze2
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Physician, scientist, educator, head of Psychiatry at @WUSTLmed. Director of Healthy Mind Lab, https://t.co/el5ZDan0a0
St Louis
Joined January 2021
Glad to publish a review of geroscience and mental health with Breno Diniz and colleagues in @AmJGeriPsych. Mental disorders accelerate aging and lead to premature mortality and dementia. Now we have pathways for intervention.
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Our second COVID treatment study available to read. Negative/failed study, but great example of a fully-remote trial.
academic.oup.com
AbstractBackground. Prior randomized clinical trials have reported benefit of fluvoxamine â¥200â
mg/d vs placebo for patients infected with severe acute resp
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Published the (negative) results of our second fluvoxamine study for COVID. We couldn't replicate our initial 2020 JAMA paper - even while other researchers did. But I'm proud of the team for the study (doing a fully remote clinical trial during COVID!).
pubmed.ncbi.nlm.nih.gov
ClinicalTrials.gov Identifier: NCT04668950.
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Great to see more evidence of fluvoxamine's efficacy for COVID-19.
ð¥ TOGETHER RCT ð¥.Treatment with oral fluvoxamine plus inhaled budesonide among high-risk outpatients with early COVID-19 reduced the incidence of severe disease requiring advanced care #IDTwitter .
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I'm excited to announce that #washu psychiatry has matched 14 EXCEPTIONAL people who will make a huge positive impact in mental health. To each of you - it was great to meet you during the interviews, I look forward to seeing you again in June.
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Exciting #childpsychiatry talk at #washu by Dr Kirsten Gilbert. Too much control = risk for psychiatric disorders (anxiety, depression, eating disorders). Her treatment research should help!
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Calling all clinical trialists! This request by #NCATS for #decentralizedtrials could be a game-changer for clinical medicine. I can't overstate how much better this could be for developing, testing, personalizing, and optimizing treatments.
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How to translate neuroscience advances into new treatments for depression, anxiety, psychosis? Adam Kepecs @KepecsLab uses novel circuitry-based phenotypes to translate from mouse to human. Great talk Adam!
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#Anxiety disorders in older adults are common, impairing, and treatable. That's the point of a new article by @paula_span in @nytimes: Thanks to US Preventive Services Task Force for advocating for research on this!.
nytimes.com
Anxiety disorders are common among seniors, but an influential panel seems likely to recommend against routine screening. Some experts disagree.
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Congratulations to Simone Bernstein, outstanding resident at @washu and Laughlin Fellow for the American College of Psychiatrists!
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Sometimes your medically hospitalized patient has demoralization, not depression! So don't start medication and contribute to polypharmacy! .That's the take-home from a great talk today at #washu psychiatry by outstanding resident Can Misel Kilciksiz MD.
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Enjoyed talk at #washu psychiatry today -- the renowned Dr Joan Luby told us how to overcome the cycle of poverty and adversity in child development. #nobelprize committee, are you listening?
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#borderlinepersonalitydisorder -- untreatable? Not so fast!.At #WashU Department of Psychiatry, Diana Whalen and her team developed an elegant, data-based conceptual model for the development of BPD -- time to invest in more research, for treatment and prevention!. Bravo Diana!
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For a GREAT summary of our recent findings in #JAMA showing no cognitive benefit in older adults from #mindfulness training or #exercise, here is a Medscape article from @fperrywilson:
medscape.com
Alas, these activities do not seem to be the fountain of youth.
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Thanks to #NIA , #NCCIH, #OBSSR, and @McKnightBrain1 for funding this project. Funding #clinicaltrials is how medical science moves forward.
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Our new study, published in JAMA today:. #exercise and #mindfulness do not boost cognitive function in older adults. Controversial? Probably. Disappointing? Maybe. But my lab will continue to test new ways to help older adults have a Healthy Mind.
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