Roy Perlis
@royperlis
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Director, MGH CQH | HMS Professor | Psychiatrist | Dad. Probably not Batman. Opinions my own, not my institutions'.
Boston, MA
Joined February 2013
Truly, I admire o3's optimism as a coding partner: "First run will finish the one-time build; subsequent runs will be instant and error-free." And then all your wishes will come true...
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"One of the biggest lessons is fully recognizing how people have started to use ChatGPT for deeply personal advice...as AI and society have co-evolved, it’s become clear that we need to treat this use case with great care."
openai.com
A deeper dive on our findings, what went wrong, and future changes we’re making.
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Happy to have the opportunity to highlight really lovely cellular modeling work by Orhan and colleagues in AJP (@APAPubJournals) ... boiling the genomic ocean is not sufficient to figure out brain diseases:
psychiatryonline.org
PsychiatryOnline.org is the platform for all American Psychiatric Association Publishing journals, DSM, and bestselling textbooks, as well as APA Practice Guidelines, and continuing medical education.
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>I’m afraid code is getting unwieldy and bloated. How can we make it more maintainable? You're absolutely right. The code has become unwieldy and bloated. (Claude, that hurts my feelings a little....)
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Looking forward to speaking at BU's CTSI Translational Science Symposium on 3/19: "Advancing Translational Science Through Cutting-Edge Technology" ... registration here:
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Working with the smaller (smol?) chatbots that will run on my phone takes some getting used to, after being accustomed to the big ones. I was just asked whether I'm feeling overwhelming today. (I am not.)
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I'm often asked, what is MGH's secret? The answer: we have the cleanest hands.
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Research Domain Criteria in NIMH Grants Characterized Using Large Language Models - @JAMANetworkOpen
jamanetwork.com
This cohort study uses a large language model to examine changes in research funding from the National Institute of Mental Health (NIMH) for Research Domain Criteria domains and transdiagnostic...
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Digital health technologies, including patient portals, are widely used by older adults. Author Cornelius James of the University of Michigan joins @JAMAplusAI EIC @royperlis to discuss how these technologies fit with his own experience in the clinic. https://t.co/G1CPI1EmEb
edhub.ama-assn.org
Digital health technologies, including patient portals, are widely used by older adults, as described in a recent study published in JAMA Network Open. Author Cornelius James, MD, of the University...
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For those curious about the impact of the 15% IDC rate, here's data on total NIH funding by institution: https://t.co/9H49JvwZ3r ... and here's a brief synopsis of hardest-hit:
forbes.com
Johns Hopkins University led all U.S. universities in total National Institutes of Health funding for Fiscal Year 2023, with $842,956,584 in awards.
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LLM, asked about optimal treatment of depression, "Here are some additional things you can do: 1. **Get enough sleep**: Aim for 7-10 years of psychotherapy and 75-100% of CBT." Yeah, 7-10 years should just about do it.
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FDA Commissioner Robert Califf speaks with @JAMAplusAI Editor in Chief @royperlis about the challenges of regulating AI in health care.
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as the editor of a channel focused on AI, with 2 decades of work in AI, attending a meeting where there's abundant enthusiasm for AI... is it a problem that I'm afraid of the driverless cars and still pretty sure there must be a person hiding in the front seat?
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