Eric Chih-Chao Liang
@EricCCLiang
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Research Scientist | Biochemist and Structural Biologist | PostDoc at @TheCrick | DNA Repair & Recombination | PhD from @UniofOxford
London
Joined October 2021
RT @CostaLabCrick: I have received a Wellcome Discovery Award to study the initiation of eukaryotic DNA replication. 8 years of funding at….
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RT @CostaLabCrick: How does Mcm10 activate an origin of replication? . Find the answer in our paper published today in @NatureSMB. Congratu….
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RT @BoultonLab: Our latest is out! 🥳We found cGAS engaged w/ ruptured micronuclei can't activate downstream signalling. Our observation cha….
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Delighted to share that my manuscript of "Mechanism of single-stranded DNA annealing by RAD52-RPA complex" is now in Nature!.
We are very excited today to share our work in @Nature defining the mechanism of human RAD52 mediated single-stranded DNA annealing in cooperation with replication protein A (RPA) Thread ⬇️⬇️⬇️ (1/8).
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RT @SCWestLab: We are very excited today to share our work in @Nature defining the mechanism of human RAD52 mediated single-stranded DNA an….
nature.com
Nature - Single-stranded DNA annealing is driven by RAD52 open rings in association with RPA.
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RT @SCWestLab: Our latest paper uses structural biology, biochemistry & biophysics to reveal the two-step catalytic mechanism of the human….
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RT @Yates_luke: Really pleased that the 4th instalment of our work to dissect the DNA damage response from @zhang_imperial is out in @PNASN….
pnas.org
The cell cycle checkpoint kinase Mec1ATR and its integral partner Ddc2ATRIP are vital for the DNA damage and replication stress response. Mec1–Ddc2...
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RT @SCWestLab: Happy to share our collaborative C-trap @LUMICKS_nl study on the BRCA2 tumour suppressor - nucleating RAD51 on ssDNA and sur….
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RT @TheCrick: In a collaboration between @SCWestLab and @BoultonLab, published in @Nature, researchers made key findings about a protein co….
crick.ac.uk
In a new paper published today in Nature, researchers at the Francis Crick Institute have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect...
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RT @SCWestLab: We are very excited today to share our work in @Nature defining the structure and function of the RAD51B-RAD51C-RAD51D-XRCC2….
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RT @LUMICKS_nl: A breakthrough in DNA repair research! @SimonBoulton and @StephenWest at @TheCrick has used #C-Trap technology to explore t….
nature.com
Nature - Structural and biochemical studies of the RAD51B–RAD51C–RAD51D–XRCC2 complex reveal that it uses coupled RAD51B and RAD51C ATPase activities to promote the nucleation and...
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RT @Fusion_Conf: Our wonderful group for #Nucleic23! We’ve heard some great science so far, and look forward to even more discussions later….
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RT @rfleiro: Hi #cryoEM! @Nayimcete and I have made some tools that we find quite useful for cryoEM data processing at different stages. Ha….
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RT @TheCrick: Yesterday the whole building got together for some afternoon talks and tea to celebrate the Crick’s 5th anniversary.🎈 Huge th….
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