Hannah Ennerfelt
@EnnerfeltHannah
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Postdoc @Stanford - Andreasson Lab | Neuroscience PhD @UVA - Lukens Lab
Palo Alto, CA
Joined December 2019
RT @kzengeler: Happy to share our work on hippocampal inflammasome signaling. Thank you to members of the lab for critical experimental sup….
cell.com
The function of immune pathways in homeostatic neurobiology remains underexplored. Zengeler et al. find that the inflammasome complex, typically associated with immune responses, is involved in...
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Check out this exciting new paper from our lab!.
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies | @ScienceMagazine
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Extremely honored to be working as a postdoc with @_BrightFocus on this project. Thank you for the support! .
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Had an amazing time at the neuroimmune @KeystoneSymp which was made even better by a reunion with @BIG_Center_UVA friends. Loved seeing you all present some stellar science!
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RT @EricTopol: Why TREM1, a pro-inflammatory factor, has become an attractive target to potentially slow brain aging and protect vs #Alzhei….
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New paper from the Andreasson lab on TREM1 in AD and aging. Congrats to @EdwardWilsonIII 🎉
nature.com
Nature Neuroscience - The role of TREM1 in neurodegenerative diseases is unclear. Here the authors show that TREM1 promotes cognitive decline in aging and in the context of amyloid pathology in a...
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A European perspective on structural barriers to women’s career progression in neuroscience | Nature Neuroscience
nature.com
Nature Neuroscience - Despite diversity, equity and inclusion efforts, women remain underrepresented as academic leaders in neuroscience. In this Perspective, Bourke, Spanò and Schuman discuss...
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RT @UVA: Dr. John Lukens is chasing a cure for diseases like Alzheimer’s and Parkinson’s in his lab at the University of Virginia. He told….
news.virginia.edu
Dr. John Lukens is on the track to mitigating or curing diseases like Alzheimer’s. Hear about it in this week’s podcast.
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RT @UVA: Touting the UVA as one of its biggest strengths, @outsidemagazine has named Charlottesville as the fifth-happiest place to live in….
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Congrats Andy and team!! 🥳.
Excited to share our work published in @ImmunityCP! We validated the human genetic findings that loss- and gain-of-function PLCG2 variants have opposite effects on transcriptional mechanisms, altering microglial phenotypes and AD pathology in mouse models.
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RT @DanielaRojo_PdD: Excited to share our work in the Gibson lab at @Stanford published in @NeuroCellPress! We show that the circadian fact….
cell.com
Rojo et al. identified that the circadian transcription factor BMAL1 is necessary to maintain oligodendrocyte precursor cell (OPC) dynamics in the mouse brain, including proliferation, morphology,...
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RT @presjimryan: Important findings from UVA researchers on how to better treat spinal cord injuries, looking at the immune system’s respon….
news.virginia.edu
UVA research has identified possible avenues to improve body’s response, which weakens with age.
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RT @LukensJohnR: Congrats to all of the 2023 UVa Graduates! @JessicaLukens @BolteAshley @EnnerfeltHannah @kzengeler @cocoholliday1
https://….
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Congrats Dr. @kzengeler !!! ✨.
Congrats to Dr. Kristine Zengeler (aka Dr. Glue) @kzengeler on a beautiful thesis defense. @uva_bims @uvaneuro Our new lab tradition is to dress up in a theme for thesis defenses. A Twilight theme was selected for Dr. Zengeler @Twilight 🍎.
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⭐️ 💫.
Lukens lab Thesis Defense announcement: .Our lab "glue" @kzengeler (the one that keeps the lab together and functioning optimally as a whole) is defending her thesis next Thurs April 6 at noon. Hit me up by DM if you want to attend by Zoom
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RT @uvahealthnews: John Lukens, PhD, and his team are neck-and-neck with the Albert Einstein College of Medicine in #STATMadness — and ther….
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RT @TheColonnaLab: The Big BAM Theory. in the paper @ImmunityCP by Simone, we described the Crybb1-Cre line, which recombines embryonic-de….
cell.com
Tools to target microglia specifically and efficiently from the embryonic development are lacking. Brioschi et al. generated the Crybb1-Cre line, which recombines in microglia and border-associated...
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Congrats to the most amazing colleague/friend @kzengeler - it’s time we know more about the mysterious and magical placenta 😍.
Sharing the power of the placenta! Check out our study looking at how the maternal-immune interface responds to inflammation and SSRI exposure and how this impacts neurodevelopment.
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Gorgeous paper highlighting in-depth microglial SYK signaling in AD. Congrats @ShoutangW and @TheColonnaLab!.
BIG shoutout to @TheColonnaLab on the wonderful story. Special thanks for being such a great colleague with the co-submission. That Marco is a real standup dude. TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways
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Happy to share our work describing microglial SYK in models of AD and MS. Thanks to all of the amazing coauthors!
cell.com
SYK is a central intracellular regulator of microglial activation and phagocytosis that is deployed to limit Aβ pathology and demyelinating disease.
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