Durga Prasanna Misra
@DurgaPrasannaM1
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Rheumatologist (Addl Prof, SGPGIMS), Epidemiologist. Vascular Rheumatology, #Takayasu arteritis, Journal editor, Hon. Treasurer @indianrheum
Lucknow, India
Joined January 2019
Delighted to be a part of this review on #Takayasu Arteritis in @NatRevRheumatol with @asawalhamd Ruchika Goel @HanerDireskenel @drfatmaalibaz @petercgrayson Kaitlin Quinn. What was special about this article was a dedication to the Late Professor @DandaDebashish, a pioneer in
New content online: Advances in the pathophysiology, diagnosis and treatment of Takayasu arteritis https://t.co/brxYbSD8Ix
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🧬 Going Beneath the Skin - Lupus Profundus Demystified 🦋 Definition: Chronic autoimmune inflammation of the deep dermis and subcutaneous fat, seen alone or with DLE/SLE. 🧬 Pathophysiology: 🔹 Immune complex & complement activation 🔹 Leads to fat necrosis → fibrosis →
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1/2 #Takayasu arteritis #TAK is a rare large vessel vasculitis #LVV. TAK more commonly affects young females.Our review in @NatRevRheumatol covers the latest in the pathophysiology, diagnosis and treatment of #Takayasu arteritis. https://t.co/ZqAYptAjzT Pathophysiology:
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Carl Sagan's birth anniversary. And what better way to remember him than my favourite quote ever, inspired by this picture taken of our planet from a spacecraft 6 billion kilometres away. “Look again at that dot. That’s here. That’s home. That’s us. On it, everyone you love,
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💖 Breaking the Chain: Blocking FcRn to Protect the Fetal Heart 🎯 Objective Assess the feasibility and safety of FcRn blockade (rozanolixizumab) to prevent recurrent cardiac neonatal lupus (cardiac-NL) in a high-risk pregnancy. 🧩 Background •💔 Cardiac-NL is due to
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Delighted to be a part of this review on #Takayasu Arteritis in @NatRevRheumatol with @asawalhamd Ruchika Goel @HanerDireskenel @drfatmaalibaz @petercgrayson Kaitlin Quinn. What was special about this article was a dedication to the Late Professor @DandaDebashish, a pioneer in
New content online: Advances in the pathophysiology, diagnosis and treatment of Takayasu arteritis https://t.co/brxYbSD8Ix
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"If Krishna is with you, you will win even if the entire world is against you"
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🩻 On This Day in History - November 8, 1895 ✨ Discovery of X-rays! ⚡ While experimenting with cathode rays, German physicist Wilhelm Conrad Röntgen noticed a strange fluorescent glow on a nearby screen - even though the tube was covered. 👀 He had discovered invisible rays
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🧬 Atacicept in IgA Nephropathy (ORIGIN 3 Trial) Background: •IgA nephropathy (IgAN) → Most common primary glomerulopathy globally. •B-cell–driven disease → Mesangial IgA immune complex deposition. •~50% progress to kidney failure or death in 10–20 years. •Atacicept =
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It is with sadness that we acknowledge the passing of Dr. James Watson, Nobel prize-winning scientist and former Director and President of CSHL. We extend our sincere condolences to his wife Liz and family during this difficult time. We recognize Dr. Watson’s incredible
cshl.edu
Jim Watson made many contributions to science, education, public service, and especially Cold Spring Harbor Laboratory (CSHL). As a scientist, his and Francis Crick’s determination of the structure...
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Congratulations @DurgaPrasannaM1 Sir 🙏🏻 Takayasu Arteritis — Nature Reviews Rheumatology 2025 (by Dr Durga P. Misra & Team ) 1️⃣ About: Takayasu arteritis (TAK) — rare, chronic large-vessel vasculitis targeting the aorta & its major branches, predominantly affecting young women
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Happy to share our multi-centre study on financial burden in Indian SLE patients.Thanks to Lupus SIG IRA and Dr.Vineeta Shobha for the opportunity 🌟1/3rd of SLE patients oncurred CHE > 20% annual income 🛑Avg expense Rs 52400/annum 🛑Max expenditure on drugs
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2/2 Management – Medical and Surgical: The management of TAK relies on immunosuppressive therapy, although the evidence for this is low, largely based on observational data. To date, no RCT has shown the effectiveness of an immunosuppressive agent against a placebo in patients
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1/2 #Takayasu arteritis #TAK is a rare large vessel vasculitis #LVV. TAK more commonly affects young females.Our review in @NatRevRheumatol covers the latest in the pathophysiology, diagnosis and treatment of #Takayasu arteritis. https://t.co/ZqAYptAjzT Pathophysiology:
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New content online: Advances in the pathophysiology, diagnosis and treatment of Takayasu arteritis https://t.co/brxYbSD8Ix
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New Oral Psoriasis Treatment Shows Impressive Results! Icotrokinra — a targeted oral peptide that blocks the interleukin-23 receptor (IL-23R) — just delivered strong Phase 3 data in plaque psoriasis. 📊 ICONIC-LEAD Trial (N=684): • Moderate-to-severe plaque psoriasis (adults
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🔄 Leflunomide Washout Therapy 💊 Why Washout Is Needed 🧬 Leflunomide → Teriflunomide (active metabolite) 🕒 Very long half-life (~2 weeks) → may persist up to 2 years 📍 Indications: 🚼 Pregnancy planned ⚠️ Severe toxicity (hepatotoxicity, pancytopenia, infection) 🔄
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