
Dharmaraja Allimuthu
@Dharma_IITK
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We are thrilled to share our latest work on small molecule lipid droplet inducers in @angew_chem. Congratulations Sai @VechalapuSai and @santhoshd22 for the excellent work. Thanks @Appu and @surithakur86, for the collaboration. @IITKanpur @Director_IITK .
onlinelibrary.wiley.com
High-fat diets and fatty acids are traditionally used to induce lipid droplet formation in cells and animals. The authors developed a new high-content imaging platform and identified functionally...
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RT @ItaiYanai: Why would anyone want to be a scientist? There are the pleasures of:.1. Having the initial idea or insight,.2. Watching the….
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RT @WasimJaffer14: Last man standing. Siraj for me is the real man of the series. The only fast bowler to play all five test with the same….
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RT @KamatLab_IISER: Test cricket is the greatest sport !!! Phenomenal series team India. Looks like we have a test team to stay !!! https:/….
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RT @bhogleharsha: Loved it that all the Indians acknowledged the bravery of Chris Woakes in coming out to bat.
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RT @ScienceMagazine: In a new Science study, researchers report a powerful tool to design small, folded protein domains that interact tight….
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RT @CellReports: Staphylococcus aureus exploits lipoic acid salvage to combat host oxidative stress
cell.com
Acosta et al. find that ADP-ribosylation of the lipoic acid carrier protein GcvH-L promotes Staphylococcus aureus resistance to oxidative burst and facilitates infection. ADP-ribosylation leads to a...
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RT @CellReports: TRIM65 as a key regulator of ferroptosis and glycolysis in lactate-driven renal tubular injury and diabetic kidney disease….
cell.com
Yang et al. demonstrate that lactate lactylates TRIM65 at K206, impairing its ubiquitin ligase activity. This blocks degradation of the iron regulator IREB2 and glycolytic gene PDK4, driving ferrop...
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RT @NatureBiotech: Chemical proteomics has brought rigor to covalent drug discovery and drugs to the clinic. Can it deliver a new generatio….
nature.com
Nature Biotechnology - Chemical proteomics has brought rigor to covalent drug discovery and drugs to the clinic. Can it deliver a new generation of drug targets?
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RT @angew_chem: Small molecules, big impact: Inducing lipid droplet formation without fatty acids. Check out new work by @Dharma_IITK: • ht….
onlinelibrary.wiley.com
High-fat diets and fatty acids are traditionally used to induce lipid droplet formation in cells and animals. The authors developed a new high-content imaging platform and identified functionally...
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RT @link_to_mk: Groundbreaking discovery from one of India’s leading chemical biologists. Kudos to you, Prof Dharmaraja Allimuthu.
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RT @surithakur86: Glad to be part of this beautiful study!! Many congratulations, Dharma and team!!!.
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RT @basker25071980: Check out our @J_A_C_S on accessing chiral C–N axes under cobalt catalysis! Congrats to @iamAbirdas @maity_pritam02 K….
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RT @Hari_Chakrapani: Nice to be back in Kaleidoscope at Udaipur this year. Excellent forum to discuss science in an informal atmosphere htt….
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RT @IITKanpur: Go beyond the lab with Prof. Sandeep Verma - acclaimed scientist, academic leader, and educator at IIT Kanpur. In this candi….
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RT @nchembio: A new paper used reactivity-based metabolomics to show that methylglyoxal and its main metabolite lactoylglutathione react ra….
nature.com
Nature Chemical Biology - Using reactivity-based metabolomics, methylglyoxal and its main metabolite lactoylglutathione were found to react rapidly with cysteines to generate l-lactoylated and...
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