Clyde Francks
@ClydeFrancks
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Prof. of Brain Imaging Genomics @ Max Planck Institute & Donders Institute, Netherlands. Biologist interested in genes, brains, behaviour, left-right asymmetry
Joined August 2014
Is genetic disposition to #dyslexia associated with brain structure? @neurosoren investigated in over 30,000 adults using data from @uk_biobank & @23andMeResearch , highlighting brain networks involved in motor, language and vision functions https://t.co/QjXUuKARnE 1/8 ⬇️
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A more detailed news article here:
thedebrief.org
New insights into dyslexia reveal structural differences in the brain linked to the genetic predisposition for this neurodiverse condition.
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Scientists discover why parents can pass on dyslexia to their children https://t.co/Vrva9UVaz3 Not how we would have put it but still appreciate the coverage (link to our press release https://t.co/kLKpoz4zRq )
dailymail.co.uk
One in every 10 people in the UK has some degree of dyslexia, according to the NHS. Scientists have now linked the genetic variants thought to cause dyslexia to changes in the structure of the brain.
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Genes, brains and dyslexia: Our study in over 30,000 adults from @uk_biobank now published in Science Advances https://t.co/OqkfIF2GEo - With a thread below from when we released a preprint version ⬇️
science.org
Genetic disposition to dyslexia is associated with brain structure in the general population.
Is genetic disposition to #dyslexia associated with brain structure? @neurosoren investigated in over 30,000 adults using data from @uk_biobank & @23andMeResearch , highlighting brain networks involved in motor, language and vision functions https://t.co/QjXUuKARnE 1/8 ⬇️
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Large-scale study links dyslexia genetics to brain structure https://t.co/4TXmYFlpL7 via @medical_xpress
medicalxpress.com
Dyslexia is a common learning difficulty in which genes often play a role. How do genes associated with dyslexia relate to brain structure in the general population? In a large-scale study published...
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Excited to see our work featured in Trends in Cognitive Sciences! Huge congratulations to the team! @Valerie_Pu @ClydeFrancks
Out now in Trends in Cognitive Sciences: a short article on studying brain asymmetry in terms of global patterns across the entire brain https://t.co/NL0Q6oBHyk Led by @xiangzhenkong and Yi Pu at Zhejiang Uni, with some contributions from myself
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Out now in Trends in Cognitive Sciences: a short article on studying brain asymmetry in terms of global patterns across the entire brain https://t.co/NL0Q6oBHyk Led by @xiangzhenkong and Yi Pu at Zhejiang Uni, with some contributions from myself
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It was nice to learn how flies 🪰🪰 can help understand some aspects of human hyperactivity, through being on the PhD exam committee of @benharich , student of @annette_schenck @BFranke_lab @_MariekeKlein_ . Congratulations Dr. Harich and supervisors!!
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So, for now, I'm staying. I hope others will too. We can't, as scientists, just spend our time talking to each other. The stakes are just too high to cede the battleground of ideas, tempting as it may be. 6/6
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Pre-adolescent Brain Asymmetry: Developmental Trajectory, Cognitive and Psychiatric Effects, Neurobiological and Environmental Influences in ABCD Study
researchsquare.com
Cerebral asymmetry is fundamental to various cognitive functions but is often disrupted in neuropsychiatric disorders. While adolescent brain growth has been extensively studied, the maturation of...
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Individualized cortical thickness asymmetry in Autism Spectrum Disorders and Schizophrenia
medrxiv.org
Introduction Cortical thickness asymmetry has been proposed as a latent biomarker for Autism Spectrum Disorders (ASD) and schizophrenia (SZ). However, the degree of abnormal asymmetry at the indivi...
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Want to do a PhD in Nijmegen on 'Mapping language-relevant genetic effects on brain variability using normative modelling' with myself, @amarquand and @ProfSimonFisher ? Applications welcome via https://t.co/ZyliYSm28i 🧠🧬
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So excited about this study led by @Annel3illoT and NiharikaJhingan: Good news for us, aging folks -- some 🧠 networks (e.g., the language one!) don't seem to deteriorate with age! Long live the language network!
[NEW PREPRINT!] The language network ages well https://t.co/3KNgDFowUf Co-led with Niharika Jhingan, in collaboration with @ev_fedorenko, @AphasiaLab, @MVarkanitsa, @raryksin, & Idan Blank. 🧵 Details 👇
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HOW DOES YOUR GENETIC CODE affect your brain? 💡A new genetic roadmap of the brain (in today's Nature Genetics) reports: 💡100s of genomic loci affect deep brain structures 💡Genetic variants driving brain volume overlap with risk loci for Parkinson's, ADHD, many brain diseases
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A 1,000,000th reminder the crucial importance of basic research. Ambros and Ruvkun were looking into understanding nematode genetics and development, not looking for a drug, and ended up opening an entire new area in biology
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@Plus3Happiness The left/right logical/holistic idea is 1% true, 99% hype. The two hemispheres do have some different functions, but it's not as simple as logical/holistic.
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Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness. New paper by @jsamelink & al. @Genes_Speak @ProfSimonFisher @ClydeFrancks
https://t.co/rTs7H6KL7q
nature.com
Communications Biology - Common and rare genetic variants, as well as polygenic scores of dyslexia and handedness are associated with the functional brain language network and hemispheric...
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First paper from the PhD of @jsamelink on the genetics of functional connectivity between regions of the brain important for language https://t.co/heBaz7H1Jb many congratulations Jitse!! @MPI_NL @DondersInst
nature.com
Communications Biology - Common and rare genetic variants, as well as polygenic scores of dyslexia and handedness are associated with the functional brain language network and hemispheric...
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Dissecting the Reduced Penetrance of Putative Loss-of-Function Variants in Population-Scale Biobanks https://t.co/x8lkA5YNZO
#medRxiv
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Assortative mating across nine psychiatric disorders is consistent and persistent over cultures and generations
medrxiv.org
Emerging evidence has shown that assortative mating (AM) is a key factor that shapes the landscape of complex human traits. It can increase the overall prevalence of disorders, influence occurrences...
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Ever wondered about #hemisphericAsymmetries in #Borderline personality disorder? We've got you covered! Check out our new systematic review in @SpringerNature ⬇️📖: https://t.co/48ZtexUANj With @ocklenBLOG and co! 🧠👩🔬 #Psychiatry #Laterality
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