Chul-Hwan Lee
@Chulhwanlee
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Working on epigenetics in development and cancer
Joined February 2025
RT @AJHGNews: 📣New from Zhou et al!.📄Applying multimodal #AI to physiological waveforms improves genetic prediction of cardiovascular trait….
www.cell.com
Health data are inherently multimodal; we developed a multimodal AI (M-REGLE) that jointly analyzes complementary physiological waveforms (like ECG and PPG) to enhance genetic discovery for cardiov...
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RT @MolecularCell: Off-pore Nup98 condensates mobilize heterochromatic breaks and exclude Rad51 .
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RT @taekjip: Non-disruptive 3D profiling of combinations of epigenetic marks in single cells
www.biorxiv.org
Recent advancements in single-cell sequencing and spatial omics technologies have enhanced our understanding of diverse cellular identities, compositions, architectures, and functions. However, the...
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RT @biorxiv_molbio: EZH1 Q571R-mediated chromatin compaction and its oncogenic potential in thyroid cancer #biorxiv….
www.biorxiv.org
Dysregulation of Polycomb Repressive Complex 2 (PRC2) contributes to tumorigenesis. Of its catalytic subunits, EZH1 and EZH2, EZH2 mutations in cancer have been extensively studied, but the role of...
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RT @MolecularCell: The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin .
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RT @tangming2005: The guide I wish I had 12 years ago: a step-by-step guide to replicate a genomics paper figure
divingintogeneticsandgenomics.kit.com
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RT @SciencNews: 🎯Breaking News #Nature . Enzyme used in meiosis makes the cut in vitro. News. Paper 1. https://t.co/….
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RT @Satpathology: Happy to share our new work describing DESynR genes! . The evolution of new human protein-coding genes relies on repurpo….
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First research paper as a PI. Paper is about HDAC3 and neurodevelopmental diseases.
🚨 Online now!.📰De novo missense variants in HDAC3 leading to epigenetic machinery dysfunction are associated with a variable neurodevelopmental disorder.
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RT @JiaRayYu1: I'm thrilled to share my lab's first manuscript identifying that paraspeckle protein NONO regulates active chromatin through….
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