Extremely happy to see the last paper of my PhD published, which focused on using cell-free DNA to detect and monitor ALS worked with an amazing cross-continent team, which was co-led by Noah Zaitlen and @FleurryG https://t.co/8p8AYArmwi

This is the last week to take our survey! If you're an early career researcher in human genetics and have some time, please consider taking our survey on how you use population descriptors It's a study run by trainees with the goal of improving trainee research quality!

Are you an early-career researcher working on the computational analysis of population-level human genetics data? We want to hear from you about if, how, and why you use population descriptors in your research! Fill out our short survey: https://t.co/7K4Ro23Bsq

If you are a trainee in genetics and have 10 minutes of time today/feel like procrastinating, please take our survey. This project is completely trainee led, and we want to get as broad of a perspective on how trainees are doing this research as possible!

A powerful alternative to principal components (PC) to account for population structure in genetic association analysis: spectral components (SPc) Compared to PC, SPc - explain more variation in population structure with fewer components (90% for SPc vs 50% for PC) - more

Are you an early-career researcher working on the computational analysis of population-level human genetics data? We want to hear from you about if, how, and why you use population descriptors in your research! Fill out our short survey: https://t.co/7K4Ro23Bsq

Hi academic friends! Does anyone have a recent-ish NIH F32 that they would be willing to share? I can’t find any online written within 10 years, but I’d be super appreciative if anyone has an example 🙂

Check out our new toolkit for cell type deconvolution from DNA methylation sequencing. Open-source and ready to use! Congrats to @UntIrene who worked tirelessly on this & thanks to @ChristaCaggiano and Noah Zaitlen who inspired us with the CelFiE approach. https://t.co/2CAyX2dHgU

How do quantities of brain cells – the fundamental unit of life – differ in Alzheimer’s disease, schizophrenia and autism? Our work on cell-type proportion shifts using methylomics is just out in @ScienceAdvances #PsychENCODE @mikejg84 @DanielVo10 https://t.co/jQDDlQKPau 🧵

So happy to have been at the beautiful UPitt for the inaugural #statgen2024. Super fun conference with lots of cool stat gen methods, definitely a new fave

Our paper looking at cell-free DNA epigenetic features in ALS is now out in MedRxiv! I am extraordinarily grateful for the ALS patients who participated in the study. This research would not be possible without them

Really wonderful work on how our genomes might interact with commonly prescribed medications

I noticed ppl disregarding the NYMag piece bc it focused on Huberman’s personal life, not bad science & harmful misinformation he propagates. So I wrote a thing. @slate: “So, Should You Trust Andrew Huberman?” https://t.co/Yp7kiLJvax

Nothing makes me as uneasy as a human geneticist as seeing the proliferation of direct to consumer polygenic risk score companies. I know academics are conservative but these scores are truly not good enough yet & have potential for true harms

so happy to see our work out in AJHG! 😊 a great collaboration during my PhD in Roel Ophoff’s lab, working with @TommerSchwarz @bpasaniuc @kangchenghou @ChristaCaggiano (and many others not on twitter) check it out!👇

The only time I’ve been called Dr since getting my PhD has been the place I order pizza from in a promotional marketing gimmick

Excited that our flagship analysis of the Mexican Biobanks is now out in @Nature

“The Iranian regime will, one day, fall. And when it does, women and men will regain their lives and their freedoms.” @TheLancet #WomanLifeFreedom #زن_زندگى_آزادى‌

?? happy to hear this company finds that measuring gene expression via RNA is better than DNA, will definitely be giving them my $200 a month!