Chaoran Chen Profile
Chaoran Chen

@ChaoranChen_

Followers
361
Following
116
Media
9
Statuses
79

PhD student at @ETH_en and developer of @GenSpectrum

Joined March 2018
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@pathoplexus
Pathoplexus
3 months
πŸ—“ Pathoplexus turns ONE! πŸŽ‚πŸŽ‰ In the past year we’ve grown from 4 pathogens to a truly global, community-driven platform for transparent, equitable & impactful pathogen sequence sharing. πŸ“° Read the full update: https://t.co/8tyR0tORdc 1/10
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@firefoxx66
Dr Emma Hodcroft
3 months
Interested to learn about how to run your own Loculus (the database code behind @pathoplexus)? πŸ€”πŸ–₯️ Sign up for the Loculus Tutorial on Mon 8 Sept at @BC2Conference in Basel, run by @ChaoranChen_ & Anya Parker! 🧬 Register: https://t.co/LI6K36lc4J #bioinformatics #openScience
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@firefoxx66
Dr Emma Hodcroft
4 months
πŸ“’New job posting!πŸ“’ Are you excited by the idea of building global infrastructure to make pathogen sequencing more accessible, interpretable, and equitable? πŸ§‘πŸ»β€πŸ’»πŸ§¬ My group at @SwissTPH has an opening working with ARTIC2, @pathoplexus, & Loculus - read on! 1/5
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@cbg_ethz
CBG, ETH Zurich
11 months
We are excited to share that our new tool VILOCA has been published in NAR G&B: https://t.co/2EfU3U0Ffn! VILOCA is a novel method for mutation calling and local haplotype reconstruction from diverse viral sequencing data, which is also adept for viral surveillance in wastewater.
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academic.oup.com
Abstract. RNA viruses exist as large heterogeneous populations within their host. The structure and diversity of virus populations affects disease progress
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@GenSpectrum
GenSpectrum
11 months
GenSpectrum just added a mpox dashboard using data from @Pathoplexus – see https://t.co/YFxRxaOePa
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@pathoplexus
Pathoplexus
1 year
Today Pathoplexus announces the inclusion of a new viral pathogen: mpox (previously known as monkeypox). Within the context of the current mpox outbreaks and ongoing health concerns, Pathoplexus aims to support sequence sharing to improve both understanding and response. 1/7
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@pathoplexus
Pathoplexus
1 year
It's wonderful to have initiatives like this to support, recognise, and reward #OpenData work. Congratulations to the other 3 fantastic winners, and to the whole Pathoplexus team, who couldn't all be with us last night! 2/2
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@pathoplexus
Pathoplexus
1 year
We're incredibly honoured to be winners of the @academies_ch @ORData_ch National Prize for Open Research Data 2024! πŸŽ‰πŸŽŠ "Pathoplexus ensures open access and provides a cutting-edge infrastructure for interactive and programmable data exploration" https://t.co/XXn8vPHsDY 1/2
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@ORData_ch
Open Research Data
1 year
⭐️And last but not least the fourth Award of the National ORD Prize 2024 goes to ’Pathoplexus’ by Emma Hodcroft, Tanja Stadler, Chaoran Chen, Alexander Taepper, Cornelius Roemer #ordprize24
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@pathoplexus
Pathoplexus
1 year
Elena Dalla Vecchia covers @Pathoplexus in @LancetMicrobe, highlighting that "Pathoplexus offers an advancement in terms of both openness and appropriate accreditation" which hopes to "become a model for similar platforms for other pathogens" https://t.co/KX5w8nZyXR
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thelancet.com
On Aug 27, Pathoplexus, a new genomic database for viruses of public health importance, was launched. Its creationβ€”supported by members from ten countries in five continents and developed in consul...
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@pathoplexus
Pathoplexus
1 year
From @PeaseRoland on @bbcworldservice β€œPathoplexus helps to protect the people uploading data so that they can share it for surveillance & public health, without feeling like they give up publishing." Listen from 8:26 at https://t.co/YMqxHSYZJ5 #Pathoplexus #OpenScience 1/2
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bbc.co.uk
A survey of diseased animals from fur farms has revealed potentially threatening viruses
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@firefoxx66
Dr Emma Hodcroft
1 year
A great article by @sciencecohen covering @pathoplexus & our values, with quotes from Exec Board member @andersonfbrito_ & the community, Eddie Holmes & @guspalpogeng! And a great excuse to deep-dive into some of the people behind Pathoplexus! πŸ‘©πŸ»β€πŸ”¬πŸ‘¨πŸΎβ€πŸ”¬πŸ‘¨πŸΏβ€πŸ”¬πŸ‘©πŸΌβ€πŸ”¬ 1/9
@pathoplexus
Pathoplexus
1 year
From @ScienceMagazine: β€œWe believe that building trust through transparency is essential for encouraging broader participation in data sharing,” says Pathoplexus co-founder Anderson Fernandes de Brito @andersonfbrito_ https://t.co/q6Xtfd762t #Pathoplexus #OpenScience
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@pathoplexus
Pathoplexus
1 year
From @ScienceMagazine: β€œWe believe that building trust through transparency is essential for encouraging broader participation in data sharing,” says Pathoplexus co-founder Anderson Fernandes de Brito @andersonfbrito_ https://t.co/q6Xtfd762t #Pathoplexus #OpenScience
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science.org
Pathoplexus is starting with sequences for Ebola strains and two other risky viruses
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@TanjaStadler_CH
Tanja Stadler
1 year
It was an amazing journey for us (our research team @ETH_en with the support of contracted software developers from TNG technology) to work with colleagues across the globe from the first idea to what we now call Pathoplexus https://t.co/krMM3TN9hr! We are very proud to 1/2
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pathoplexus.org
Pathoplexus is a new, open-source database dedicated to the efficient sharing of human viral pathogen genomic data, fostering global collaboration and public health response.
@pathoplexus
Pathoplexus
1 year
πŸ“’ We're excited to introduce Pathoplexus, a specialized sequence database for human viral pathogens! 🌍 🧬 Launching with 4 viruses, https://t.co/4wGez2nTCr combines modern open-source software with transparent governance to improve global pathogen sequence sharing. 1/14
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@pathoplexus
Pathoplexus
1 year
πŸ‘‹πŸ» You can read our full introduction at https://t.co/rqa6Egvq1x, as well as checking out: - ❀️ Our Values ( https://t.co/WYo264UHvx) - πŸ”“ Open Data Use ( https://t.co/VU73vPmgWz) - πŸ”’ Restricted Data Use ( https://t.co/Ng9SqwBQks) - πŸ§‘πŸ»β€πŸŽ“ Our Exec Board ( https://t.co/zCmSzguCTE) 2/14
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@pathoplexus
Pathoplexus
1 year
πŸ“’ We're excited to introduce Pathoplexus, a specialized sequence database for human viral pathogens! 🌍 🧬 Launching with 4 viruses, https://t.co/4wGez2nTCr combines modern open-source software with transparent governance to improve global pathogen sequence sharing. 1/14
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pathoplexus.org
Pathoplexus is a new, open-source database dedicated to the efficient sharing of human viral pathogen genomic data, fostering global collaboration and public health response.
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@TanjaStadler_CH
Tanja Stadler
1 year
DECODING GENOMES - from sequences to phylodynamics: We are proud to present our book on how to analyse genomic sequences with an evolutionary perspective. See https://t.co/seRPOVuCyi for a free pdf, Amazon links for print orders, and further information. Great team effort 1/2
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@GenSpectrum
GenSpectrum
2 years
Interested in developing dashboards and tools for public health and genomic epidemiology? We are looking for a software engineer to join our GenSpectrum team at @ETH_BSSE in Basel, πŸ‡¨πŸ‡­CH! https://t.co/2uu0JTj1Fi Please reach out if you have any questions and please share! :)
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@theosanderson
Theo Sanderson
2 years
I am a researcher studying viruses. I have contributed to the sequencing of more than a million genomes deposited in the GISAID database. Last week I found that my access to bulk downloads from GISAID had been cut off without cause or explanation. [1/3]
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@theosanderson
Theo Sanderson
2 years
πŸ“„ πŸ“„ Our molnupiravir work is now out after peer-review! We definitively demonstrate that molnupiravir has resulted in viable SARS-CoV-2 viruses with significant numbers of mutations, in some cases with onwards transmission of mutated viruses.
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nature.com
Nature - A specific class of long phylogenetic branches, distinguished by a high proportion of G-to-A and C-to-T mutations, are almost exclusively found in sequences from 2022, after molnupiravir...
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