Chris Mahony
@C_B_Mahony
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Genomic scientist and mountain lover
Birmingham, England
Joined July 2018
Our article about the adaptive radiation and social evolution of the ants is now out in Cell! We analyze 163 ant genomes to explore the evolution of these amazing social insects 🐜 Check it out: https://t.co/WuErVgVbQf
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🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!
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InSituCor: exploring spatially correlated genes conditional on the cell type landscape https://t.co/1twEWl4ge1 🧬🖥️🧪 https://t.co/sDCLThAETM
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CHOIR is now online @NatureGenet! CHOIR is a new clustering method for single-cell data that evaluates whether clusters represent statistically distinct cell populations. CHOIR scales to millions of cells and works with single-/multi-omic data of any type! https://t.co/EKg20yMygH
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KnockTF: a comprehensive human gene expression profile database with knockdown/knockout of transcription factors Now KnockTF 2.0 👤🐭🌱🌽 >1400 transcriptomes ~800 TF/TcoF https://t.co/UsioREswPL Go to "Search" for your TF "Quick Search" does not work @NAR_Open 2020
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Introducing RAEFISH, our lab's new flagship image-based spatial transcriptomics technology that simultaneously enables single-molecule spatial resolution and whole-genome level coverage of long and short, endogenous and engineered RNA species in cell cultures and intact tissues.
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PASTE2 Partial alignment (based on a subset of spots) of multi-slice #SpatialTranscriptomics 3D reconstruction of 16-slide Stereo-seq Drosophila embryo Partial fused Gromov-Wasserstein #OptimalTransport vs PASTE Pamona Tangram Alignment evaluated with Label Transfer
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Unagi: Deep Generative Model for Deciphering Cellular Dynamics and In-Silico Drug Discovery in Complex Diseases https://t.co/McE50tQ0gZ
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transfactor: Transcription factor activity estimation via probabilistic gene expression deconvolution https://t.co/XURTMQibMV
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Identification and characterization of cell niches in tissue from spatial omics data at single-cell resolution https://t.co/WvZo8KPnJ3
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Spotiphy (spot imager with pseudo-single-cell-resolution histology), a computational toolkit that transforms sequencing-based spatial transcriptomics data into single-cell-resolved whole-transcriptome images. https://t.co/DonTPn3HXR
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Still time to apply! We’re hiring at CHU Sainte-Justine, join our lab! 🐠🩸
🚨 The Ghersi Lab is Hiring! 🚨 If you're passionate about hematopoietic stem cells, developmental biology, and cutting-edge research, I’d love to hear from you. Feel free to share. 🩸🐠 📍 Montreal, Canada 📩 joey.ghersi.hsj@ssss.gouv.qc.ca and https://t.co/j3bDZvHLss
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COVET: The covariance environment defines cellular niches for spatial inference https://t.co/esVrYZ8SNK
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nf-VueGen: Automating the generation of scientific reports (with Nextflow) https://t.co/CXHP6mupyo 🧬🖥️🧪 https://t.co/tGJyLYuvub
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Decoding aging-dependent regenerative decline across tissues at single-cell resolution https://t.co/shh9k7PLNk Open stem cell research from @CellStemCell
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Interested in exploring @vevo_ai’s massive Tahoe-100M single-cell perturbation dataset? #Scanpy now supports out-of-core analysis, powered by Dask—allowing you to seamlessly work with a single huge AnnData object without loading everything into memory. 🔗 https://t.co/1r2GMJxBXy
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GitHub - omnideconv/spacedeconv: A unified interface to spatial transcriptomics deconvolution tools
github.com
A unified interface to spatial transcriptomics deconvolution tools - omnideconv/spacedeconv
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Smoothie: Efficient Inference of Spatial Co-expression Networks from Denoised Spatial Transcriptomics Data https://t.co/j7X4fl9sHG
biorxiv.org
Finding correlations in spatial gene expression is fundamental in spatial transcriptomics, as co-expressed genes within a tissue are linked by regulation, function, pathway, or cell type. Yet,...
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Scaling up spatial transcriptomics for large-sized tissues: uncovering cellular-level tissue architecture beyond conventional platforms with iSCALE😳 https://t.co/Ch1cqvPNp5
biorxiv.org
Recent advances in spatial transcriptomics (ST) technologies have transformed our ability to profile gene expression while retaining the crucial spatial context within tissues. However, existing ST...
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goloco: a web application to create genome scale information from surprisingly small experiments https://t.co/3UO29d3HPV
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