 
            
              CTCPR Trials & CIRL
            
            @CTCPR_
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              Center for Translational Cardiology and Pragmatic Randomized Trials / Cardiovascular Non-Invasive Imaging Research Laboratory. Led by Prof @TorBiering
              
              Herlev & Gentofte Hospital
            
            
              
              Joined August 2020
            
            
           Volume 4 Issue 11 of ๐๐๐๐ ๐๐ท๐ช๐ฅ๐ฆ๐ฏ๐ค๐ฆ is now available! Here is a preview of the latest content: ๐ข๐ฟ๐ถ๐ด๐ถ๐ป๐ฎ๐น ๐๐ฟ๐๐ถ๐ฐ๐น๐ฒ๐ Cardiac Effects of Dapagliflozin in People with Chronic Kidney Disease  https://t.co/UZvHJetjv0 
          
          
                
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             Happy to see the main results from our DECODE-CKD trial published in @NEJMEvidence. Yet another unique trial from the @CTCPR_ team, and in particular congratulations to the coordinating investigator @katjabartholdy ๐ Please find the paper below ๐  https://t.co/uic19h6hsJ 
          
          
            
            evidence.nejm.org
              Adverse cardiac remodeling is common in people with chronic kidney disease and contributes to increased cardiovascular risk. Although sodiumโglucose cotransporter 2 (SGLT2) inhibitors have shown ca...
            
                
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             ๐ The final keynote of #ESWI2025 featured Tor Biering-Sรธrensen (@TorBiering, University of Copenhagen, ๐ฉ๐ฐ) presenting the FLUNITY-HD study โ a pooled analysis of the DANFLU-2 and GALFLU trials linking influenza vaccination to cardiovascular protection๐โค๏ธ #Vaccines #PublicHealth
          
          
                
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            @CTCPR_ was well represented at #IDWeek with rising ๐ @AM_reimer giving a LBCT presentation on the immunocompromised subgroup from the DAN-RSV trial and a poster presentation on the immunocompromised subgroup from the NUDGE-FLU CHRONIC trial. ๐ publications coming out soon.
          
          
                
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             ๐ฌ @CTCPR_ FLUNITY-HD study, published in @TheLancet, reveals that the High-Dose influenza vaccine provides superior protection against hospitalisations compared to the conventional Standard-Dose. Nearly 500,000 participants aged 65+ were individually randomized โ the first 
          
                
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             Influenza and heart dysfunction ๐ซ๐ฆ  A new interim analysis from the FluHeart Study by @CTCPR_ shows that patients with influenza frequently develop left and right ventricular dysfunction. Cardiac impairment was worse than in matched general population controls and comparable to 
          
                
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             NUDGE-FLU trial: Promoting one vaccine can influence uptake of another ๐ฆ ๐ A prespecified secondary analysis of the nationwide NUDGE-FLU trial by @niklasdj1,ย  and colleagues @CTCPR_ found that electronic letters promoting influenza vaccination slightly reduced COVID-19 
          
                
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             Infections can trigger heart attacks & strokes โ but vaccines can serve as a preventative tool!๐ซ๐ A consensus between European Interdisciplinary Council for Aging (EICA) and the Italian Society for Cardiovascular Prevention (@SIPREC_it) , including @TorBiering from @CTCPR_, 
          
                
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             RSV infection and cardiovascular risk ๐ซ A nationwide @CTCPR_ study in @JACCJournals by @matslassen & colleagues shows adults โฅ65 have a 4โ8ร higher risk of heart failure hospitalization and ischemic stroke in the 14 days after acute RSV infection. ๐ก Highlights the need for 
          
                
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             ๐ซ Global longitudinal strain (GLS) under the spotlight! A new @CTCPR_ study in @JACCJournals defines a key cutoff for patient risk: ๐ GLS < 16% is the lower normal limit across ultrasound vendors โ and predicts heart failure hospitalization in elderly & at-risk individuals 
          
                
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             ๐ New insights by @Espersen_C and colleagues @CTCPR_ | @CircAHA Cardiovascular disease (CVD) affects 11% of the Danish population and remains the second leading cause of death, responsible for โ12,000 deaths annually. Despite Denmarkโs universal healthcare, social and 
          
                
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             ๐ Insights on heart hospitalizations in US vs Denmark from @CTCPR_ ! US has 1.5ร higher rates, bigger income gaps, especially in MI & HF. Highlights how healthcare and social factors shape outcomes. ๐ Dive deeper:  https://t.co/88E6SIxp8M 
            @JAMACardio
          
          
                
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             Iโm more than proud to lead a team of the most talented researchers I have ever met ๐ฉโ๐๐ง๐ฝโ๐Congratulations to the whole team with this accomplishment ๐ Itโs an honor to work with and learn from you all ๐ @CTCPR_ for the win ๐ 
           ๐จ An extraordinary achievement from all the @CTCPR_ researchers at ESC! Our researchers simultaneously published 13 papers across leading journals, showcasing some of the latest breakthroughs in cardiology. These publications include: ยท 3 in The New England Journal of Medicine 
            
                
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             .@TorBiering has entirely changed the game & transformed the clinical trial landscape! #DANFLU2 #GALFLU #DANRSV provide a glimpse at the possibilities of randomizing at scale & addressing fundamental unanswered questions. Hats off to @niklasdj1 @matslassen & entire @CTCPR_ team 
          
                
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             ๐จ An extraordinary achievement from all the @CTCPR_ researchers at ESC! Our researchers simultaneously published 13 papers across leading journals, showcasing some of the latest breakthroughs in cardiology. These publications include: ยท 3 in The New England Journal of Medicine 
          
                
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             What an incredible #ESCCongress2025! Privileged to hang out with the likes of @DLBHATTMD @mvaduganathan @rkwadhera @RahulAggarwalMD and to call @TorBiering my boss! Three simpubs as 1st author will not be easy to top, but that is definitely the goal next year! 
          
                
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             Editorial: Recent advancements and clinical trials emphasize the importance of recognizing #RSV as a health threat in older adults, with vaccines offering protection against severe disease and potentially broader cardiopulmonary benefits. #ESCCongress #WCCardio
          
          
                
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