Manan Pareek, MD, MSc, PhD, FAHA, FESC
@MananPareekMD
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CV fellow @RigsHeart | Editorial fellow @JAMA_current | MSc in Clinical Trials @Oxford_NDPH | Residency @YaleIMed | Research fellow @BrighamFellows
Copenhagen, Denmark
Joined July 2020
1/ Time to talk about high-sensitivity cardiac troponins (hsTn) in a little more detail: https://t.co/e8qgolhJ18
@CopCard @HGHHjerte @CIRL_DK @DLBHATTMD @mvaduganathan @TorBiering @Pallisgaard_MD
academic.oup.com
AbstractBackground. Long-term prognostic implications of serial high-sensitivity troponin concentrations in subjects with suspected acute coronary syndrome
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Yet another one of @TorBiering’s discoveries - @LauraMariaAdam - just halfway through med school and already teaching us about the utility of lung ultrasound in acute heart failure at #AHA25! @CTCPR_ @fdavidovski_MD @Espersen_C
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Keeping up with this topic is really exhausting. Stop everything—here’s a new meta-analysis, this time in patients with myocardial infarction and preserved ejection fraction (≥50%). The first piece of news is that, after I don’t know how many years since the last cardiovascular
nejm.org
The benefit of beta-blockers after myocardial infarction in patients with a preserved left ventricular ejection fraction (LVEF) is unclear. We conducted a meta-analysis at the individual-patient le...
I wouldn’t exactly call myself a black belt in beta-blockers, but with all this talk of superiority, "non-superiority," and "non-non-inferiority," it’s really enough to get confused. If I interpret correctly the avalanche of trials from the past year, accompanied by the
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We are hiring yet again👇 This time we are looking for skilled medical doctors, interested in clinical research. Come join the most innovative and creative team, and help us in redefining how we should conduct randomized controlled trials in a more efficient and inclusive way.
🚨 News from @CTCPR_: We are looking for a PhD Fellow to join our team and support ongoing research projects. Help us advance cardiology research and contribute to meaningful studies. 🔗 Apply here: https://t.co/Wcp0CHbku4
@TorBiering
@Stenodiabetes
@CopCard
@Rigshospitalet
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Thrilled to have presented not just one, but two late breaking featured science abstracts on FLUNITY-HD - and to have shared the stage with superstars like Daniel Modin, @ankeetbhatt, @SheilaHegde, @orlyvardeny - grateful to @TorBiering, @niklasdj1, @CTCPR_ for the opportunity!
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Extremely proud of mentee Anna Meta (with zero SoMe presence) who presented the findings from an IPD meta-analysis of RCTs on beta blockers after MI in patients with preserved LVEF - no effect in this setting! Simultaneous publication in NEJM: https://t.co/3LvQ6BYo2z
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Had a great time at #AHA25 in New Orleans. Always a pleasure to hang out with the @CTCPR_ crew, @DLBHATTMD, and finally got to meet @Ajar_Kochar in person - also presented @drJBorchsenius’ beautiful poster on CRP concentration and risk of stroke in patients with MI!
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Our most recent publication from FLUNITY-HD published simultaneously with the LBCT presentation by @MananPareekMD. We find that HD flu vaccines are associated with significantly lower risk of cardiovascular and respiratory hospitalizations than SD flu vaccines. @CTCPR_ @niklasdj1
#AHA25 The high-dose influenza vaccine appears to provide broader protection against severe cardio-respiratory events than standard-dose vaccine in older adults including those with established cardiovascular disease https://t.co/kYjd5tOcAt
@niklasdj1 @KiraJanstrup @TorBiering
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Incredible job @niklasdj1 (and DANFLU-2/GALFLU teams)💉🦠👏🏼
🔬 @CTCPR_ FLUNITY-HD study, published in @TheLancet, reveals that the High-Dose influenza vaccine provides superior protection against hospitalisations compared to the conventional Standard-Dose. Nearly 500,000 participants aged 65+ were individually randomized — the first
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One of the adaptive designs we are seeing more frequently is the Sequential Multiple Assignment Randomised Trial (or SMART trial) 1/7 #MethodologyMonday #126
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We are accepting applications for the JAMA Editorial Fellowship Program. This remote fellowship is an opportunity for early career researchers to immerse themselves in the editorial process of a top-tier medical journal and receive hands-on mentorship from a JAMA Editor. 🔗
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I wouldn’t exactly call myself a black belt in beta-blockers, but with all this talk of superiority, "non-superiority," and "non-non-inferiority," it’s really enough to get confused. If I interpret correctly the avalanche of trials from the past year, accompanied by the
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In this #JACC Editor’s Page, EiC Dr. @hmkyale critiques the outdated physician certification system, arguing it’s misaligned w/ real-world practice & fuels burnout w/out proven patient benefit 🎧 Listen here or wherever you get your podcasts https://t.co/dtAxOzFhYy
#JACCPodcast
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If you use less skilled workforce to replace more skilled workforce then this happens: 1) worse outcomes 2) increased appointments and activity 3) increased waiting lists 4) costing the tax payer far more If this sounds perverse and idiotic - then you need to do something
The NHS is falling apart, yet doctors are blocked from caring for patients. In 2025, 20,000 more applied than there were available training posts to become Consultants/GPs. Doctors are being shut out because the Government won’t fund enough speciality training & post CCT places.
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To be clear, there are no data that provide a link between short-term use of Tylenol during pregnancy and autism. In fact, one of the best prospective studies w/ sibling controls, if anything, pointed to a protective effect for use less than 7 days https://t.co/HmBji9CmxK
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6-8 hours of sleep is associated with larger brain volumes. 7 hours is associated with the highest cognitive functioning.
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NEW PAPER "The STARD-AI reporting guideline for diagnostic accuracy studies using #artificialintelligence" in @NatureMedicine --> https://t.co/7IGGyF4MPK
#machinelearning #digitalhealth #transparency
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The new #LancetCommission obesity definitions show dramatic differences in risk: 🏈 Athlete, BMI 32—WHO called it class I obesity; now “no obesity” 👵 Older woman, BMI 27+diabetes—WHO overweight; now stage 2 clinical obesity 👩 Woman, BMI 33+prediabetes—WHO class I; now stage 1
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📢 Join our webinar on sex and gender reporting in research 📅 Tues, 21 October, 2pm BST 👉 Register: https://t.co/eN8IwIvLsG Our editors will guide you through our requirements for sex- and gender-based analyses, and share practical tips and examples of well-analysed research
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This is going to be a fantastic late breaking featured science session at #AHA25. Come meet me, @niklasdj1, @ankeetbhatt, and Daniel Modin on November 10! @TorBiering @CTCPR_ @RigsHeart
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