The Barrangou Lab
@CRISPRlab
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News from the @NCState CRISPR Lab! Student run account.
NC State University
Joined March 2016
Be sure to take a look at our latest use of CRISPR in forestry!
Bringing CRISPR to forestry... Check out our work with Jack Wang @FBG_NCSU: Multiplex CRISPR editing of wood for sustainable fiber production | Applications and Implications...
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Take a look at our most recent publication from the lab. Congrats @theCRISPRdrawer!
Excited to share my first, first-author research article, with @CRISPRmatt @CRISPRchef, out now in @NAR_Open: https://t.co/W8egPnsPWp 1/
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Check out our latest paper from the lab. Congrats to @CRISPRmatt, @theCRISPRdrawer and @Claudio_HCantab.
Latest paper from the lab showing how we can use CRISPR to manipulate the microbiome. @PNAS, https://t.co/HA9zCId86R,
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Congratulations to our graduate student Echo Pan for using CRISPR to engineer the next generation of probiotics! https://t.co/8oolxgQMm5
pnas.org
Bifidobacterium is a commensal bacterial genus ubiquitous in the human gastrointestinal tract, which is associated with a range of health benefits....
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Check out our new research featured on @GENbio. We established a CRISPR-based genome editing platform for Bifidobacterium, an important bacterial genus for human health. Paper coming out in PNAS soon!
#Microbiome Engineering: Individualized #CRISPR Approaches to Advance Next-Gen #Probiotics Researchers have reported advances in understanding and manipulating Bifidobacterium, an important bacterium in the microbiome of the human gut. Read more: https://t.co/teSNoBm4oj
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Excited to publish our collaborative work on šš¢š¤šµš°š£š¢š¤šŖššš¶š“ bile salt hydrolases with the Theriot lab in PNAS! @TheRiotMicrobe
pnas.org
Primary bile acids (BAs) are a collection of host-synthesized metabolites that shape physiology and metabolism. BAs transit the gastrointestinal tr...
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On this date in 2008, Marraffini and Sontheimer floated an idea: moving CRISPR into eukaryotes could enable RNA-guided gene targeting. Little did theyĀ know that 12 years later, thanks to many brilliant colleagues in ourĀ community, CRISPRād patients would walk among us.
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Congratulations!!! We shall henceforth redefine the field historyĀ as CRISPR BC (Before Charpentier, relatively few peopleĀ cared about CRISPR) and genome editingĀ AD (After Doudna, everybody cares about genome editing). Predictable, defensible, momentous! @doudna_lab @NobelPrize
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T-minus two hours until "Human Nature" premieres! Discover the extraordinary new technology called CRISPR, which we can now use to edit DNAāincluding human DNA. But first, what is #CRISPR and how does it work? https://t.co/PXUV50LzDM
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Thrilled to announce that the @FDA has cleared Caribouās first IND for a CRISPR #genome-edited off-the-shelf allogeneic anti-CD19 CAR-T #celltherapy candidate for patients with relapsed/refractory B cell non-Hodgkin #lymphoma. Read more here:
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Great job to Echo Pan on her 3 minute flash talk for the Genetics and Genomics Initiative!
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New paper looking at S-layer associated proteins in L. acidophilus. Congrats @CourtneyEKlotz on the publication of your final PhD paper!
link.springer.com
BMC Microbiology - Surface layers (S-layers) are two-dimensional crystalline arrays of repeating proteinaceous subunits that form the outermost layer of many bacterial cell envelopes. Within the...
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TreeCo, a company co-founded by @NCStateCALSās Rodolphe Barrangou (@CRISPRchef) and our own Jack Wang, will use tree genetics and genome editing to make forestry into an industry that can meet the needs of society.
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We are happy to announce our first official Impact Factor -- 5.343 (courtesy @webofscience). Thank you to everyone who has published, reviewed, commentated, read and cited our papers over the past 2.5 years! It takes a community. Congrats to @CRISPRchef and our superb EAB. 1/3
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A company founded by @NCStateCALS researcher Rodolphe Barrangou (@CRISPRchef) and @NCStateCNR researcher Jack Wang is working to revolutionize the #forestry industry through the power of #GenomeEditing. See what it means for the future: https://t.co/gMLZeAFju7
#ThinkAndDo
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We are excited to share STOPCovid, an inexpensive, one-step, & sensitive #COVID-19 detection protocol developed with @omarabudayyeh & @jgooten. This revamped assay was streamlined with the future goal of developing an in-home test for COVID-19. https://t.co/AhGrm6NYvz 1/X
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In preparation for #ShutDownSTEM tomorrow, 10 June, @ScienceMagazine Science has made the following articles available without subscription or registration to help facilitate discussion.
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Peter Harries of @ncsugradschool : "As an institution of higher education, we have a responsibility, not just to advance diversity and inclusion, but to fight injustice and racism." Today we take the day to educate ourselves and to identify actions we can take. #ShutDownSTEM
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We've certainly been staying busy while working from home! We have a brand new paper out looking at #CRISPR-Cas systems in #Bifidobacteria
@CRISPRchef @CRISPRmatt @ClaudioCRISPR
https://t.co/GAquBdJpRY
mdpi.com
The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas (CRISPR-associated cas) systems constitute the adaptive immune system in prokaryotes, which provides resistance against...
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