Hysterectomy / BSO & Stroke Risk — What’s new?. 🧩 Study type: NHANES 1999–2018 cohort + meta-analysis of 16 studies (total ≈2.07 million women). Published in Menopause (Sept 2, 2025). Headline findings. Hysterectomy (vs none): HR 1.09 (95% CI 1.04–1.15; P=0.001) → +9% higher.

B is for Body Fat — Implementing the new clinical obesity definition in preventive cardiology. 🧭 Big idea :.Move from “B is for Body weight” to “B is for Body fat”—assess adiposity with ≥2 measures (e.g., BMI + waist), classify preclinical vs clinical obesity, and act early to

🧪 CME INDIA Update. Novel Drug for Cushing’s Syndrome – Relacorilant Shows Metabolic & CV Benefits.ENDO 2025 | GRACE & GRADIENT Phase 3 Trials. 🔑 Key Findings. 📉 Blood Pressure:.• Systolic ↓ –10.1 mmHg vs +1.5 (placebo).• Diastolic ↓ –6.3 mmHg vs +2.2 (placebo). 🍬.

A step closer to making PCSK9 inhibition accessible, acceptable, and scalable in everyday practice. Oral PCSK9 Inhibitor Enlicitide Decanoate – Landmark CORALreef Lipids Phase 3 Trial Results.Shared by Dr. T.V. Narayan Rao, Vijayawada. 🔬 Merck reports that enlicitide decanoate,

CME INDIA INPUT.Key Elements. A – Age. Age ≥80 years (sometimes ≥65 with frailty/comorbidities) → reduced physiological reserve and altered pharmacodynamics. Older adults are more sensitive to medication side effects and adverse events. B – Behavioral / Cognitive decline.

A–G Mnemonic for Deprescribing in Elderly T2D. Shambo Samrat Samajdar .Department of Out-Patient Clinic, Diabetes and Allergy-Asthma Therapeutics Specialty Clinic, Kolkata, India and and .Shashank R. Joshi.Department of Endocrinology, Joshi Clinic, Mumbai, India.@AskDrShashank

Answer. D. 💊 Aficamten vs Metoprolol in HOCM (MAPLE-HCM Trial, NEJM 2025). 🧩 Clinical Background. HOCM ≠ simple LVH → It’s a distinct genetic cardiomyopathy with LVOT obstruction and risk of sudden cardiac death (SCD). First-line till now: Beta-blockers (Metoprolol).

CME INDIA MCQ (By Dr Satish Kumar). Which is the best drug for Hypertrophic Obstructive Cardiomyopathy (HOCM) as monotherapy?. A. Metoprolol.B. Amiodarone.C. Ivabradine.D. Aficamten.E. Digitoxin. Answer . will be posted later.

Clinical Case Note. Case Presentation:.A tall, thin 28-year-old male presents with primary infertility of 3 years’ duration. His wife reports regular menstrual cycles, making a female factor less likely. Examination Findings:. Small, firm testes. Minimal facial hair.

Data-Driven CSF Proteomics in SLE: Links to Clinical Phenotypes.(Elsa Grenmyr et al., ACR Open Rheumatology, Aug 28, 2025).@hyderabaddoctor @RheumNow.@Rheumat_Aravind @12VRavindran.🔹 Background:. CNS involvement in SLE is heterogeneous and difficult to predict. CSF proteomics

Early Gestational OGTT & Biomarkers for GDM Risk.(International Prospective Multicentre Cohort Study, 2025). 🔹 Background:. No clear consensus on how to risk-stratify women in early pregnancy for later development of Gestational Diabetes Mellitus (GDM). This multicentre study

Regular azelastine spray reduced risk of SARS-CoV-2 infection. 🚨 Azelastine Nasal Spray for COVID-19 Prevention. Phase 2 Randomized Clinical Trial (JAMA Intern Med, Sept 2025). 🔑 Why important?.Pharmaceutical pre-exposure prophylaxis options for COVID-19 remain limited.

Very illuminating .@GastroHub.--CME INDIA

We dont add years ! We add life to their years !*- Interventional Pulmonology in Palliative Care . Dr Viswesvaran MD, DM,Lead Consultant- Interventional Pulmonology ,Yashoda Hospitals, Somajiguda, Hyderabad. 72 year, female . Known case of Squamous cell carcinoma of esophagus

ESC Clinical Consensus Statement on Obesity & Cardiovascular Disease (Eur Heart J, Aug 2025) — 10 key points. 🚨 ESC Clinical Consensus Statement on Obesity & CVD (2025). 10 Key Points → CME INDIA Clinical Pearls. 📌 1. Rising burden. Prevalence of obesity has more than doubled.