Chromosome Biology and the Cell Cycle at Newcastle
@CBCC_NCL
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Studying how cells organise, inherit and make use of the genetic and epigenetic information in chromosomes.
Newcastle Upon Tyne, England
Joined May 2020
We've merged! Our Chromosome Biology and Cell Cycle Theme has joined 2 other Themes @nubiosciences @NCL_medresearch to now become the super Theme🙂 'Cells, Genes and Molecules'. Please join in and follow us on our new page @CGM_NCL
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Congratulations to everyone involved in our latest review: https://t.co/CMsTyZFbJy . An amazing accomplishment that was led by two early career researchers in the team. Well done Dan @DanCKent, and Leti @LetiziaM24 . @danielrico_bio @AnetaMikulasova @NU_Cancer
onlinelibrary.wiley.com
Broad H3K4me3 domains have evolved in the last decade since their identification, recently associated with H3K27ac. They enable the identification of cell identity and tumour suppressor genes. The...
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Our study found a simple, one-off treatment with senolytics was able to prevent long-term side effects of cancer radiotherapies involving #MiceInResearch. It gives hope to 2 million cancer survivors, many facing premature memory loss. https://t.co/ExvANZ0DCN
ncl.ac.uk
A new study has found that a simple, one-off treatment was able to prevent long term side effects of cancer radiotherapies.
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On Tuesday 23rd May it’s The Fight Against Antimicrobial Resistance with @GiusyM1990 (soon to be at @UniSurreyBioSci) and @Ch_Winterhalter @EngageFMS @CBCB_Newcastle . Tickets at https://t.co/Ggwnrza8iq 3/4
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Exciting development in liver cancer immunotherapies here from @derekamann1 and team! https://t.co/FNFXo3rRMh
@UniofNewcastle
ncl.ac.uk
Pioneering immunotherapy treatment being developed at Newcastle University could help liver cancer patients to live longer and better lives.
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👏 congrats to all authors!
We identified a molecular mechanism where DnaD binds ssDNA at the origin of replication to promote bidirectional helicase loading in B. subtilis. @NAR_Open Thanks @heathmurraylab, @simopelliciari and cryoEM expert @ilango_aravind! https://t.co/NCkg5Sb2JA
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🔊 Calling all Newcastle FMS post docs!One week to go to get your abstracts and best paper submissions in for the FMS post doc symposium! Deadline 28th April. Submit here! https://t.co/S5NxPuPyxE
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New publication 🎉 Very pleased to see our paper is out at @CellReports: Cyclin A and Cks1 promote kinase consensus switching to non-proline-directed CDK1 phosphorylation https://t.co/6PwhF5hdmM
cell.com
Cyclin-dependent kinase (CDK) substrate phosphorylation varies in a cell-cycle-dependent manner. al-Rawi et al. develop a fixed cell kinase assay to study CDK1 kinase substrate choice proteome-wide...
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Our MRC DiMeN DTP PhD student Emily Archer Goode has published a review in Oncology Letters ‘Prostate cancer bone metastases biology and clinical management’ https://t.co/AikyZUTlNR Congratulations Emily on a fantastic article 🎉 @DiMeN_DTP @NU_Cancer @ProstateUKProfs
spandidos-publications.com
Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.
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Great week for the Rice group 👏
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DNA methylation analysis identifies key transcription factors involved in mesenchymal stem cell osteogenic differen… https://t.co/oPe03R7jU2
@RMSCT_NCL @mattbarter
pubmed.ncbi.nlm.nih.gov
In this work we describe an osteoblastogenesis-associated DNA-methylation profile and, using these data, validate a novel computational tool to identify key TFs associated to age-related disease...
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Chile has been involved in a very interesting collaboration on bone cancer that is just coming out - see some more details in this press release from Newcastle University
ncl.ac.uk
Researchers have developed a new drug that works against all the main types of primary bone cancer.
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Excellent news @GrainOfScience. Well done Sarah
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We are advertising a Lecturer/Senior Lecturer position in Metabolomics at Newcastle University. we are looking for an ambitious your researcher using #massspec based metabolomics. If you are interested in joining @nubiosciences
#academicjobs
https://t.co/DZAbSg3FgT
jobs.ncl.ac.uk
Lecturer/Senior Lecturer in Metabolomics
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It's Sustainability Week at Newcastle University! Why not come join us at our first event today?🌼🌿 Check out our programme full of great in-person and virtual events that you can get involved in this week: https://t.co/dTjGLNMJbN
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New work out from the @VIKorolchuk lab 😊. Reviewing the two pillars of longevity with @niall_wilson
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Calling potential PhD students. There's still 4 days left to apply for our new PhD position available @NU_Cancer. Are you interested in developing advanced cell-based modelling systems for one of the most fatal brain tumours in childhood? See:
findaphd.com
PhD Project - PhD studentship in Childhood Brain Tumour Research: Unlocking the translational potential of the MYC-dependent proteome in medulloblastoma using advanced cell-based 3D-modelling...
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New work from Beccy Harris et al. (Higgins + Rico labs). An element of the "histone code" that may not work as we thought... @nubiosciences @NU_Cancer @lukegaughan22
biorxiv.org
Histone modifications influence the recruitment of reader proteins to chromosomes to regulate events including transcription and cell division. The idea of a histone code, where particular combinat...
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