See bronchial Beaker cell from @IHeartHisto - I will provide an appropriate bounty for the best (or any) Gritty cell.

Blood, sweat, and beers: investigating mosquito biting preferences amidst noise and intoxication in a cross-sectional cohort study at a large music festival

Cool approach to use bi-specifics to target cell surface receptors for therapy: ALK1-BMPRII agonism by clustering bispecific antibodies treats hereditary hemorrhagic telangiectasia

Thrilled to share the next chapter in my career — I’ve been named the inaugural Chair of the Department of Dermatology at Mass General Brigham (MGB). It’s an incredible honor to lead such an accomplished, innovative team—arguably the most forward-thinking in our field.

For those of you paying attention - I do not think an open letter entitled "The Great Barrington Declaration" reeks of humility.

This has a thoughtful response that highlights a lack of critical thinking from our current leadership. https://t.co/GOkd9amy4L via @statnews

For those with an interest in enteric infections (or if you have had Beaver Fever) - this commentary summarizes recent studies on the potential benefits of Giardia. Public offering of shares in ParasitesAreUs to come....

Subscribe on the PATH website to get details of upcoming general information Zooms ahead of the letter of intent deadline.

New in @SciImmunology! @EmilyAunins, Dr. Anthony Phan, and their colleagues in the @WeissmanLab and Hunter Lab (@KingOfPathogens) used lipid nanoparticles encoding IL-12 to boost CD8 T cell responses to mRNA vaccines. 📃 https://t.co/0chkzWVDqm 🎧 https://t.co/vvDVzU06M6

What a week: I was lucky enough to get an ERC Advanced Grant, a Wellcome Trust Discovery award, and my fab colleagues at Inflammazoom nominated me for this BSI award. Thank you so much

Improving T-cell responses to vaccines ft. @emilyaunins (@CAMBUPenn), @KingOfPathogens, Anthony Phan (@PennVet), Susan Domchek (@PennCancer), @WeissmanLab (@PennMedicine), @MgAlameh (@PennPathLabMed) & @SCOTTeHENSLEY (@PennMicro) @SciImmunology https://t.co/MO8IDNdGA8

ITCH revolutionized veterinary medicine and what is considered a BLOCKBUSTER drug and a major indication. Apoquel (JAK inhibitor) was approved in 2013 for canines and literally sold like hotcakes. Itch in dogs is now a $multiBILLION dollar market: 🧵

Drawing attention to our senior immunology student Mark Maynes who published his MRI and spectral flow cytometry methods to measure neuroinflammation and neurodegeneration in dementia models. Nice job Mark! @markmaynes_ https://t.co/lVCjX2mv30

Get your proposal together for BWF PATH's 2026 awards! Letter of Intent deadline is July 17, 2025

Here, grad student Zach Lanzar and @synthekine used engineered IL-12 protein to understand how IL-12 causes toxicity (its not just NK cells) and how variants that bypass NK cells can be used.

Other groups were concerned about IL-12 toxicity associated with repeat treatments with IL-12 mRNA and took a clever approach to reduce toxicity.

The last week has seen a convergence of studies looking at how to use IL-12 and approaches to overcome toxicity. Just a brief recap for @CytokineSociety @NatRevImmunol Single doses of the mRNA encoding IL-12 enhances mRNA vaccine induced CD8 T cells

Ever wondered about IL-12 toxicity? Here we build off Garcia labs and @synthekine to de-couple immune parameters and toxicity associated with IL-12 agonism: Cell Reports

Sharing Dr Marina Seady’s comprehensive review published in Trends in Neuroscience regarding CD8 T cell mediated blood-brain barrier disruption. Great job Marina! @marinaseady https://t.co/cPXFb5VKlL

Microbial Pathogenesis Peeps - New Investigators - this one is for you! Easy first round one pager. Break out your imagination and think of those high risk-reward projects and risks you want to take.... https://t.co/TgPsbzEnQx

We previously showed that IFNg is required for CAR-T efficacy in solid tumors, but is it always good? Here, we show that IFNg limits CD28 CAR-T cells and that protection from this signal drives greater antitumor activity and durability. Enjoy! https://t.co/W7SY1akJ6X