ChrisHunter
@KingOfPathogens
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Scottish Cytokine Immunoparasitologist @KingOfPathogens.bsky.social
Philadelphia
Joined November 2019
See bronchial Beaker cell from @IHeartHisto - I will provide an appropriate bounty for the best (or any) Gritty cell.
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RT @BWFPATH: Subscribe on the PATH website to get details of upcoming general information Zooms ahead of the letter of intent deadline.
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RT @ImmunoPodcast: New in @SciImmunology!. @EmilyAunins, Dr. Anthony Phan, and their colleagues in the @WeissmanLab and Hunter Lab (@KingOf….
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RT @ClareBryant13: What a week: I was lucky enough to get an ERC Advanced Grant, a Wellcome Trust Discovery award, and my fab colleagues at….
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RT @PennMedCSO: Improving T-cell responses to vaccines ft. @emilyaunins (@CAMBUPenn), @KingOfPathogens, Anthony Phan (@PennVet), Susan Domc….
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RT @itchdoctor: ITCH revolutionized veterinary medicine and what is considered a BLOCKBUSTER drug and a major indication. Apoquel (JAK inh….
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RT @DrAaronJJohnson: Drawing attention to our senior immunology student Mark Maynes who published his MRI and spectral flow cytometry metho….
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RT @BWFPATH: Get your proposal together for BWF PATH's 2026 awards! . Letter of Intent deadline is July 17, 2025.
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Here, grad student Zach Lanzar and @synthekine used engineered IL-12 protein to understand how IL-12 causes toxicity (its not just NK cells) and how variants that bypass NK cells can be used.
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Other groups were concerned about IL-12 toxicity associated with repeat treatments with IL-12 mRNA and took a clever approach to reduce toxicity.
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The last week has seen a convergence of studies looking at how to use IL-12 and approaches to overcome toxicity. Just a brief recap for @CytokineSociety @NatRevImmunol Single doses of the mRNA encoding IL-12 enhances mRNA vaccine induced CD8 T cells
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Ever wondered about IL-12 toxicity? Here we build off Garcia labs and @synthekine to de-couple immune parameters and toxicity associated with IL-12 agonism: Cell Reports
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RT @DrAaronJJohnson: Sharing Dr Marina Seady’s comprehensive review published in Trends in Neuroscience regarding CD8 T cell mediated blood….
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Microbial Pathogenesis Peeps - New Investigators - this one is for you! Easy first round one pager. Break out your imagination and think of those high risk-reward projects and risks you want to take.
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RT @StefanieBailey_: We previously showed that IFNg is required for CAR-T efficacy in solid tumors, but is it always good? Here, we show th….
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Ohh - so cool. For lovers of THE interferon.
We previously showed that IFNg is required for CAR-T efficacy in solid tumors, but is it always good? Here, we show that IFNg limits CD28 CAR-T cells and that protection from this signal drives greater antitumor activity and durability. Enjoy! .
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RT @MiriamMerad: 25 years ago, I came to Stanford on a J1 visa and worked so hard to be worthy of that privilege. Today, I lead Immunology….
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RT @KedmiRanit: Incredible! Over the past 2 months, 5 independent manuscripts — from @TheColonnaLab, Dan Littman, @gardnerlabUCSF and @them….
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