Brian Miller
@BrianC_Miller
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Card-carrying immunologist and oncologist at UNC Chapel Hill.
Chapel Hill, NC
Joined October 2009
They never tell you that the glamorous life of a PI includes hot gluing the lid of your LN2 tank back together to save $400 on a cheap piece of plastic and styrofoam.
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Super excited to share our latest work with @MarcelaMaus , out this week in @Nature. We show that in vivo CRISPR screens can identify genes that enhance the efficacy of CAR T cell therapy. Brief explainer below! @MGBResearchNews @broadinstitute
https://t.co/rUM3TAjkPu
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π¨ New Target for cSCC Immunotherapy! π¨ Immune checkpoint VISTA, linked to strong T cell activation in cutaneous SCC @theJIDJournal
#CancerResearch #Immunotherapy #VISTA #cSCC #immunecheckpoint #Oncology #skincancer #dermatology @YaleCancer @yalederm
https://t.co/z48CnuB3Co
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Congrats to my PhD student Omar Budayr on his 1st author review titled: Harnessing extracellular vesicle-mediated crosstalk between T cells and cancer cells for therapeutic applications Use this link for 50 days of free access to the article: https://t.co/hetu88r8P1
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.@OncLive named Ethan Basch (@EthanBasch1), MD, MSc, FASCO, as one of the 2024 Giants of Cancer Care for his pioneering research in the field of patient-reported outcomes.
unclineberger.org
OncLive named Ethan Basch as one of the 2024 Giants of Cancer Care for his pioneering research in the field of patient-reported outcomes.
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When you had planned to work on a grant tonight, but instead drive into lab to empty your alarming -80C freezer. #YoungPILife
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Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens https://t.co/4UVmPI1uXP
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Celebrating the career of Shelley Earp @UNC_Lineberger at a recent joint retreat between our Molecular Therapeutics and Clinical Research programs. Shelley has been a beloved and incredibly effective Director of our cancer center for over 20 years. π©΅
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Always fun to see great science from great labs (and great friends). @DebattamaSen
nature.com
Nature Immunology - Cancer and aging are associated with each other, but underlying mechanisms contributing to this correlation are unclear. Here the authors identify a dysfunctional T cell state...
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Excited to share our latest work on engineered probiotic yeast to treat colitis led by Mairead Heavey! Check it out here: https://t.co/rSUVxn7tP7
@UNC_Health_Care news story here: https://t.co/cV23vD2QPc
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We'd like to give a shout-out to Alex Bastian, PhD, Postdoctoral Scholar @UNC_Lineberger. Dr. Bastian was nominated for how well he brings a teaching approach to the lab.
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Today, Boom announced the successful flight of XB-1, the world's first independently developed supersonic jet, at the Mojave Air & Space Port in Mojave, California. Flown by Chief Test Pilot Bill "Doc" Shoemaker, XB-1's inaugural flight marks a major milestone toward the return
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A real joy spending time with a good friend and mentor during his visit to @UNC_Lineberger. Pretty impressive what they're building over at @ArsenalBio. You're welcome back anytime, @nickhaining, and I promise the crowd will serenade you again before your talk.
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.@theNCI awarded a $3.2 million grant to Jen Jen Yeh (@YehlabUNC), MD, and Gary Johnson, PhD to support the first metastatic pancreatic cancer trial to evaluate whether treatment by tumor subtype will help match to more effective therapies. @UNCPancreas
unclineberger.org
The grant will support the first metastatic pancreatic cancer trial in the country to evaluate whether selecting treatment by tumor subtype will help patients match to more effective first-line...
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Exciting opportunity to join the @WilliamKimMD Lab as a Research Technician! I highly recommend joining this collaborative lab to study bladder and kidney cancer using innovative techniques. More information in the flyer below π! @UNC_Lineberger @UNCurology @UNCUroOnc
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Excited to share our paper in @NatImmunol describing X-CHIME, a CRISPR-based system for knocking out genes in immune cells constitutively, inducibly, sequentially, and lineage-specifically.
nature.com
Nature Immunology - Sharpe and colleagues devise a conditional gene deletion model in mice for rapid sequential, combinatorial and lineage-specific interrogation of gene function in hematopoietic...
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The Patient-Centered Outcomes Research Institute (@PCORI) has awarded Ethan Basch (@EthanBasch1), MD, MSc, FASCO, $3 million in research funding to support an initiative to implement electronic patient-reported outcomes, or ePRO, in oncology practices.
unclineberger.org
PCORI has awarded funding to support an initiative implementing electronic patient-reported outcomes in oncology practices across the U.S.
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New paper: Most approved drug combinations for advanced cancer (1995-2020) have predictable clinical efficacy, because they have additive effect on Progression-Free Survival times. In @NatureCancer at https://t.co/Z7xabVpouT by @HaeunHwangbo @SC_Patterson @PlanaDeborah 1/6
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