Bleichert Lab
@BleichertLab
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Find us @Yale focusing on chromosome replication: structure and function @YaleMBB #CryoEM
Yale University
Joined July 2020
Our study on how the human MCM2-7 helicase is loaded onto replication origins 🧬 is now online @Nature! 🎉. Our findings reveal that unlike in yeast, human MCM loading does not require ORC6 and can occur through multiple pathways. Read more here:
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RT @CostaLabCrick: Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! ❄️🔬🧬🎉🥳 . Great colla….
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RT @groth_anja: Great kickoff for the EMBO EMBL Replication symposium with amazing structural and functional insights into initiation, elon….
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RT @YaleMBB: We're excited to announce a tenure-track or tenured faculty position in Cellular Biophysics and Structural Biology! We are esp….
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Congrats to grad students Ran Yang and Olivia Hunker for giving a wonderful talk at the MB&B retreat and also for winning poster awards!. The lab had a great time socializing with our colleagues and hearing about all the amazing work being done in the department.
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Incredibly cool work from our lab neighbors!!.
Our high-resolution (2.2 Å) in situ structural work reveals details of translational landscape, with various cofactors and antitumor drug/inhibitor, all directly within human cells!.
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RT @RonBreaker: Here is a recent posting for a Lecturer position with the Department of Molecular Biophysics and Biochemistry (MB&B) at #Ya….
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Beautiful work from our lab neighbors!.
High-res In-situ Structures of Mammalian Respiratory Supercomplexes in Reaction within Native Mitochondria Check out my lab's first work on membrane proteins!.Yes, we knew nothing about detergent😜, so we directly imaged proteins within native membrane!
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Thank you to everyone who came to our Thanksgiving themed science social on Friday. We had a wonderful time sharing food, drinks, and conversation with you all! Also shout-out to our co-hosts in @LabPaulsen for doing a fantastic job!
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RT @RonBreaker: Yale MB&B is seeking a Lecturer to contribute to our educational mission. Please consider joining our scientific community….
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RT @cientificolatin: Our GSMI panel “Grad Student Panel on: PhD admissions in the Biological Sciences” will be NEXT WEEK on10/23 at 2:30pm….
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The lab had a great time at the @YaleMBB retreat last week. Congrats to Olivia for delivering a fantastic talk and to Ran for winning the poster award!
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RT @YaleMBB: Congratulations to graduate student poster award winners, The Pengxin Chai, Ran Yang, and Chrishan Fernando! .
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Excited to see this story finally in press! Happy to be a part of the team and congrats to everyone involved. 👇🎉.
Nature research paper: Acetyl-methyllysine marks chromatin at active transcription start sites
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RT @butterwicklab: Yale is hosting the 10th NE Cryo-EM Symposium Oct 27th - should be a great day full of exciting talks and posters! Regis….
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RT @ernstschmidd: We folded over 40,000 pairs of ~300 human #genomemaintenance proteins with #AlphaFold multimer. Check out all the struct….
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Taking a moment to check out the beautiful beach @CSHL before the start of #CSHLdnarep . Excited for a great meeting!
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