Bin Liu
@BinLiu49077152
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Postdoctoral Fellow, RNA Therapeutics Institute, UMass Medical School @ESontheimerLab @xue_lab #CRISPR
Joined June 2019
RT @RTI_UMassChan: Hot off the press from the RTI: Prime assembly with linear DNA donors enables large genomic insertions . https://t.co/….
pubmed.ncbi.nlm.nih.gov
Targeted insertion of large DNA fragments has promising applications for genome engineering and gene therapy1,2. Twin prime editing (PE) guide RNAs (pegRNAs) have enabled relatively large insertions,...
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RT @OSUGeneTherapy: 🧬We are thrilled to announce that Bin Liu, PhD (@BinLiu49077152) has joined the Gene Therapy Institute! Bin completed h….
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RT @RTI_UMassChan: #RNATx2024 CRISPR Therapies: How Can Genome Editing Become a Standard of Care?. Keynote: Jennifer Doudna[@doudna_lab],….
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A beautiful structure for the split prime editor (sPE).
Nature research paper: Structural basis for pegRNA-guided reverse transcription by a prime editor
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RT @NatureBiotech: Targeted genome editing with a DNA-dependent DNA polymerase and exogenous DNA-containing templates .
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RT @Ruoxi52101264: Amazing teamwork and great mentorship! Thanks, Eric and team!!! Looking forward to more exciting discoveries of ER-phagy….
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RT @somaticediting: 🆕#SCGE publication in @NatureComms: Template-jumping prime editing enables large insertion and….
nature.com
Nature Communications - Retrotransposons replicate their genetic information through target-primed reverse transcription (TPRT). Here the authors report a template-jumping prime editor (TJ-PE) to...
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RT @jwattsgroup: Contrary to expectations, many patients with Fragile X syndrome express RNA from the FMR1 locus. The RNA is mis-spliced bu….
pnas.org
Aberrant alternative splicing of mRNAs results in dysregulated gene expression in multiple neurological disorders. Here, we show that hundreds of m...
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RT @Marcus_Ruscetti: It was pleasure to write this Preview with @linzhou0515 highlighting back-to-back papers online today in Cancer Cell t….
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RT @Marcus_Ruscetti: Thrilled to share our recent paper published online today at @NatureCancer led by our talented postdoc Lo Chibaya and….
nature.com
Nature Cancer - Ruscetti and colleagues show that the pancreatic cancer tumor microenvironment suppresses immune surveillance following therapy-induced senescence via repression of inflammatory...
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RT @Nature: Nature research paper: Ubiquitin-like Conjugation by Bacterial cGAS Enhances Anti-phage Defence
nature.com
Nature - Cap2 of the cyclic dinucleotide-based anti-phage immune system functions through a ubiquitin-like conjugation mechanism to regulate cGAS activity.
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RT @Foijer_lab: Online now @Nature, our lab’s latest paper showing that cells with a chromosomal instability (CIN) phenotype rely on cGAS-S….
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RT @npariente: And it's a wrap with information on #CRISPR2022!.(and #CRISPR2023 will be in lovely Wurzburg). Thank you @dbikard @Stinekeva….
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RT @NatureBiotech: A split prime editor with untethered reverse transcriptase and circular RNA template https://t.c….
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RT @ESontheimerLab: New ePub drop today:.Prime editors and petRNAs* unleashed. *prime editor template RNAs. And I describe our split PE (….
nature.com
Nature Biotechnology - A split prime editor simplifies delivery.
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RT @ESontheimerLab: It was a great collaboration with @xue_lab, spearheaded by @BinLiu49077152 and @xiaolong_dong. With crucial contributio….
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RT @ElementoLab: Wow - lots of high-level job transitions announced today! William Pao heading to Pfizer to head drug development, Hans Cle….
endpoints.news
Pfizer has found its new chief of drug development, and they’ve dispatched a raiding party to Basel to pluck him off the executive committee at Roche. William Pao, who took ...
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RT @xue_lab: Our PEDAR paper is online at Nature Biotech.This work is conceived and led by Tingting Jiang. We are b….
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