Breanna Zerfas
@BLZerf6
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Joined March 2013
If you are in the Boston area at the end of October do not miss our free, in-person networking event on Wednesday, October 29th from 5:30-7:30pm! Thank you so much to @KymeraTx for hosting. Register below at this link: https://t.co/CRsiyTcuUe
eventbrite.com
In conjunction with the 8th TPD & Induced Proximity Summit
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Was great to work with this team to develop an IRE1a PROTAC. Make sure you check it out!
'Linkerless' PROTACs? Structure-guided design of a truncated heterobivalent chemical probe degrader of IRE1α - now published in @rsc_medchem
https://t.co/Er8AKYSG7n
#PROTAC #TPD
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For the first TPD webinar of 2025, we are thrilled to welcome @DennisWhom from @drughuntersite to share industry highlights in targeted protein degradation & induced proximity. 🗓️ Jan 9 | 🕛 12 PM EST Open to all, register for free at: https://t.co/eUffvS1yeQ
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We are looking for a Scientist to join us in the Fischer lab to work on proteomics-based projects. If you are interested in big data problems and using proteomics as a research tool take a look at the job description and apply now! https://t.co/FC6rCXcEW9
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Excited to be able to continue our annual event this September!
The DFCI TPD organizing team is excited to announce the date for our third in-person TPD meeting! Program details to come....
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Interested in learning about the newest methods to identify ubiquitylated proteins? Join us next week for a ubiquitin focused session featuring talks from the groups who developed E-STUB, BioE3 and Ub-Pod!
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Join our next TPD Webinar, 2nd May, 11AM EDT/ 8AM PT/ 4PM BST / 5PM CEST @conway_group, @PatrickJosephB - 'Bringing Bump-and-Hole to Molecular Glues: The Development of Orthogonal IMiD-Degron Pairs' @DianeHaakonsen - 'Stress Response Silencing in Neurodegenerative Disease'
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Can we conjugate ubiquitin in a non-canonical fashion? Join @BLZerf6 and me for two compelling seminars at 11 am EDT, 8 am PT, 4 pm BST, 5 pm CEST: @JonathanOstrem: “Direct Small Molecule Ubiquitination” Darci Trader: “Bypassing an E3 Ligase for TPD"
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We are looking for a postdoctoral research fellow to work with Eric Fischer and myself to pioneer next-generation covalent drug discovery. Please retweet. Apply here: https://t.co/BucBEiSGW2
@fischerlab1
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March 7th at 11am EDT we will have Ryan Potts of @Amgen speaking in our TPD seminar series sharing some insights on how proximity-based therapeutics has redefined druggability! Very much looking forward to this seminar!
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Despite some initial technical difficulties, @HartungIngo gave a can’t miss talk on how to define what makes a good chemical probe for degraders in our TPD webinar. Watch it on our YouTube channel now!
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Excited to get this preprint out! ByeTAC: Bypassing an E3 Ligase for Targeted Protein Degradation
biorxiv.org
Targeted protein degradation utilizing a bifunctional molecule to initiate ubiquitination and subsequent degradation by the 26S proteasome has been shown to be a powerful therapeutic intervention....
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So excited to host next week’s TPD webinar with @HartungIngo! Join us on January 25th at 11 AM eastern #tpd #dfci #webinar
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We are excited to open our 2024 seminars this week with two fantastic speakers! We will be hosting 2019 Nobel Laureate Bill Kaelin and Matt Boudreau of the @kaelin_lab to speak about Screening for Natural Product Degraders.
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Join us for our last DegradoZoom of 2023, featuring University of Bonn's Radek Nowak @RPNowak on 'Structure-based Design of Covalent Cereblon Binders' and Christian Steinebach @c_steinebach on 'Targeting the Ubiquitin-Proteasome-System with PROTACs.' Thursday, Dec 14th, 11am EST
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Looking forward to having @xinzhoulab join us in our next TPD seminar to share some of the work that is happening in her lab here in the @DFCI_ChemBio and @DFCI_CancerBio departments!
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Congrats, @RPNowak! Can’t wait to see the great things to come from the Nowak lab!
NEWS! I'm excited to share that I'm joining @IsbBonn @UniklinikBonn @UniBonn @ImmunoSens as a professor to start my LAB! We are open for business and #hiring for #postdoc #tech positions! #NewPI #MoveToGermany #UniBonn #TPD #InducedProximity Please share!
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Happening today at 11 AM EDT!
Looking forward to our AI focused session this Thursday at 11am EDT!
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Happening today at 11 am EST!
Join us tomorrow at 11 am EST for a seminar focusing on UBR5, one of this summer's "hottest" ligases. Featuring speakers @jonathanMtsai, Jacob Aguirre, @KevinGMark, and @DurgaKolla427. Ebert Lab, @LabThoma, @RapeLab
https://t.co/h4et0Ym9bh
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