Trader Lab
@DJTraderLab
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Medicinal Chemistry and Chemical Biology Lab @ UC Irvine
Irvine, CA
Joined March 2018
RT @Keribackus: Thrilled to share our new study in @nchembio describing the proteome-wide impacts of electrophile stress in the context of….
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RT @nchembio: A new paper from @TheAlbrecht_Lab and @LJSeabrook developed a targeted protein degradation platform, MrTAC, that enables argi….
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RT @LJSeabrook: I’m so excited to welcome MrTAC to the world of targeted protein degradation! We created a chemical inducer of arginine met….
nature.com
Nature Chemical Biology - Development of a targeted protein degradation platform, methylarginine targeting chimera (MrTAC), enables arginine methylation-driven degradation of intracellular proteins...
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Congrats Cody and Saayak on your immunoproteasome probe paper!.
chemistry-europe.onlinelibrary.wiley.com
The ONX-0914-alkyne probe described here allows for the conjugation to a variety of fluorophores through click chemistry. It can then be used to visualize immunoproteasome activity in gel-based,...
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Excited to see this happening. Go proteasome stimulation!!!
linkedin.com
Introducing Booster Therapeutics! I’m very proud to announce the debut of Booster Therapeutics 🚀 With $15M in seed financing from Apollo Health Ventures and Novo Holdings, we are pioneering a new...
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RT @UCI_SPPS: UC Irvine’s Pharmacological Sciences PhD Program is hosting a VIRTUAL Info Session on Wed, Sept 11 from 12 pm – 1 pm PST. Joi….
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Congrats @CodyLoy45 on your RSC ChemBio paper on a caged luciferin probe for the immunoproteasome!.
pubs.rsc.org
The immunoproteasome (iCP) can be expressed under inflammatory conditions, such as exposure to interferon-gamma (IFN-γ), that alerts the cell to begin generating iCP preferentially over the standard...
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Congrats @CodyLoy45 on your recent review on the proteasome's primed substrate channel!.
mdpi.com
Protein homeostasis is a tightly conserved process that is regulated through the ubiquitin proteasome system (UPS) in a ubiquitin-independent or ubiquitin-dependent manner. Over the past two decades,...
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RT @CodyLoy45: Had an amazing experience at my first Bioorganic Chemistry GRC! From the exciting talks to making some incredible friendship….
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Huge congrats to these FIVE amazing PhD candidates in the lab! Cody Loy, Kate Kragness, Tim Harris, Duno Dantis, and Jaida Osman
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RT @DMHuryn: We have an opening for a #chempostdoc in the @DMHuryn lab to work on our med chem / chemical biology kidney disease project.….
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RT @UCI_SPPS: Discover the secrets to PhD success! 🥼🔬. Listen to @TheAlbrecht_Lab on her tips to becoming a successful PhD student at @UCI_….
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RT @ChemicalBiology: The @OnoPharmaFound sponsors a terrific series of Webinars in #chembio and this upcoming one will be excellent. Please….
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When your trainees have too much time on their hands, they make your lab into proteasome people!
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RT @WendtLab_cancer: The is looking for postdocs interested in collaborative work in breast cancer metastasis, nove….
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Looking forward to our session today 2-5pm in Room 356! Targeting Protein Homeostasis Networks and Recent Developments Towards Targeting the Proteasome with Small Molecules #ACSSpring2024 @DMHuryn.
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RT @LynJonesChemBio: We are looking for a postdoctoral research fellow to work with Eric Fischer and myself to pioneer next-generation cova….
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Congrats Eslam and Thanks @ACS_DivBioChem !!!.
Congrats to @EslamAl47351670 from the @DJTraderLab at @UCIChemistry on receiving an #ACSDBC Student Travel Award to #ACSSpring2024! Check out Eslam’s poster on Sunday night!
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RT @MingjiDai: Sometimes we only make half of the natural product. Check out our collaborative work with the Zhang lab and @DJTraderLab in….
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