Arnaud Blomme
@ArnBlomme
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Head of the Laboratory of Metabolic Regulation @GIGA_Uliege; #mRNAtranslation and #cancermetabolism; Former MSCA 🇪🇺 and CRUK 🏴 fellow
Joined July 2018
What a great way to start the new year! Congratulations @Gysurf and @FendtLab for this fantastic story linking cancer metabolism and mRNA translation now out in @Nature. Thanks for having us on board! @pierreclose1 @GIGA_ULiege Please see the thread below 👇
Beyond excited to share that the main work of my PhD on how aspartate signaling drives metastasis is finally out in @Nature ✨ -> https://t.co/TrgXGM2Glg A huge thank to the @Fendtlab and all our collaborators for the terrific team work 🙏 @KU_Leuven @vib_ccb A brief🧵
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Congratulations @MJNokin on this exciting piece of work. Another evidence that targeting ferroptosis has an enormous clinical potential, but the timing and the context should be carefully evaluated. @GIGA_ULiege @UniversiteLiege @televie @frsFNRS @Ferroptosis1 @Ferroptosis2306
"In vivo vulnerabilities to GPX4 and HDAC inhibitors in drug-persistent versus drug-resistant BRAFV600E lung adenocarcinoma" out on @CellRepMed by our #OncoAlertAF 🚨Colleague @BiagioRicciutMD 🇺🇸and Team https://t.co/3kaR56dkAI This study investigates the vulnerabilities of
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Online now! Concurrent loss of LKB1 and KEAP1 enhances SHMT-mediated antioxidant defence in KRAS-mutant lung cancer https://t.co/QBH9k0L0r9
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Check out our new publication @NatureComms . Our studies found that G6PD is essential for KL but not KP lung tumorigenesis. Thus, targeting G6PD could be a potential therapeutic strategy for tumors with KRAS and LKB1 co-mutations.
nature.com
Nature Communications - Cancer cells rely on NADPH to manage oxidative stress and support biosynthesis. Here, the authors show that glucose-6-phosphate dehydrogenase (G6PD) ablation suppresses...
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On my way back from @ISCaM_Society . What a fantastic meeting that was! Amazing science done by fantastic scientists! Also extremely proud of our PhD students that did a terrific job in representing the lab. It was a blast! @MorganePaque @pierreclose1 @GIGA_ULiege
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Final of a fantastic @ISCaM_Society conference! A stellar lineup of speakers! If you're around don't miss this afternoon's lipid metabolism session with our two @GIGA_ULiege superstar students @MorganePaque and #notwitterNing giving updates on their respective projects #proudPI
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Back in 2017 I was sitting in a pub with @JohannesMeiser to celebrate his moving from @CRUK_SI to @LIH_Luxembourg, hoping for a common future in academia. Flashforward 2024: our #cancermetabolism project has just been funded by @frsFNRS @televie and I can't be happier! #ProudPIs
RÉSULTATS | ❤️ @televie : Les 12.239.019,49 € récoltés en 2024 financeront 90 projets et 99 scientifiques dans la recherche contre le cancer ! https://t.co/iLz5uFmMDb ➕ Le communiqué de presse : https://t.co/0PZzqVDKEw
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💫NEW: @pierreclose1 & co show that MAPK therapy upregulates valine aminoacyl-#tRNA synthetase and alters fatty acid oxidation, providing a resistance mechanism that may be therapeutically targeted. #melanoma #TherapyResistance
https://t.co/31bOSX1SFm
nature.com
Nature Cell Biology - El-Hachem et al. show that MAPK therapy upregulates valine aminoacyl-tRNA synthetase and alters fatty acid oxidation by promoting translation of valine-enriched transcripts,...
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Father’s diet influences son’s metabolic health through sperm RNA
nature.com
Nature - Small mitochondrial RNAs in sperm sense paternal obesity.
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And thank you to @SohailTavazoie lab for the nice news & view nicely putting Najla's work into perspective!
📢Latest @NatureCellBio:"Valine aminoacyl-#tRNA synthetase promotes #therapyresistance in #melanoma" by El-Hachem, @pierreclose1 & co. #cancerresearch 👉Read N&V by @QiushuangW & @SohailTavazoie : https://t.co/zgcy4a9Qq5
https://t.co/xflqrrpiiw
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Happy to share the latest publication from the @pierreclose1 Lab out today in @NatureCellBio! A groundbreaking study connecting mRNA translation and metabolism from a cool angle! 🙌 to @hachem_najla! https://t.co/6HEvTUV38r
@UniversiteLiege @GIGA_ULiege @frsFNRS @FondationFcc
nature.com
Nature Cell Biology - El-Hachem et al. show that MAPK therapy upregulates valine aminoacyl-tRNA synthetase and alters fatty acid oxidation by promoting translation of valine-enriched transcripts,...
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Looking for a postdoc? Why don't you join us in beautiful Belgium to do some cool science and have lots of fun! Great mentorship and fantastic international collaborators provided (we also have good beers 🍻!). Thanks for sharing 🙌 @GIGA_ULiege @televie @frsFNRS @Stkstichting
I am recruiting a talented and dedicated postdoc! tRNA epitranscriptomics-immunoOncology Please apply @ pierre.close@uliege.be https://t.co/LQiPruDEYd
@Translacore @EACRnews @epitran @TSI_lab_LIH @ArnBlomme
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Patient-derived xenograft (PDX) models allow cancer researchers to study tumour tissue from patients in mice. Our @CRUKLungCentre paper @NatureComms describes 48 new PDX models and highlights the importance of intratumor heterogeneity in the development of cancer models (1/9)
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Congratulations @JohannesMeiser ! Another milestone for you! Great duo with @FrezzaLab too 🔥
Presenting metabolomics analyses: what’s in a number? As part of a methods advice series, Meiser and Frezza highlight frequent pitfalls and offers guidance related to designing, processing, and communicating metabolomics analyses @JohannesMeiser @FrezzaLab
https://t.co/cQlDaPbf7d
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Ever wondered how to present your #metabolism #data best? A new #methods commentary series @embojournal gives advice! To start @JohannesMeiser and Christian Frezza @FrezzaLab present guidance on how to reliably present and interpret #metabolomics results:
embopress.org
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Open #PhDposition in #translational #lungcancer research where we use #proteomics and #bioinformatics to improve #precisionmedicine. Very excited about this and hope to see many applicants that wants to help cure cancer! 😃 https://t.co/EBShXlGQ0G
kidoktorand.varbi.com
Do you want to contribute to top quality medical research? To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individu
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Hey everyone - Pls RT - we’ve got a great position open for a talented #postdoc scientist to join us @HiLIFE_helsinki @helsinkiuni to study the spatial organization of #metabolism in #intestinal #stem cells and #cancer! Interested? Just get in touch. Apply by the 4th of May aka
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