Alex Trapp
@AlexandreTrapp
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biologist & pianist @retrobio_
Redwood City, CA
Joined June 2021
Last week, on the cover of @NatureAging, we published the first computational framework for epigenetic age estimation at single-cell resolution. A fantastic collaboration with @CsabaKerepesi and @VadimGladyshev in the @gladyshev_lab @harvardmed! https://t.co/2QXfmVqXh4 1/๐งต
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Our Founder and CEO, @dullunlivin, takes the stage to talk about our advocacy efforts and the bipartisan Longevity Science Caucus!
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Reaching this milestone has been truly significant for us. Please join us at the H-SPAN Summit at @Georgetownโs new Capitol Campus!
๐ ๐ฎ๐ฟ๐ธ ๐ฌ๐ผ๐๐ฟ ๐๐ฎ๐น๐ฒ๐ป๐ฑ๐ฎ๐ฟ๐! ๐ข๐๐ฟ ๐.๐. ๐ฆ๐๐บ๐บ๐ถ๐ ๐ฟ๐ฒ๐๐๐ฟ๐ป๐ โ ๐ฟ๐ฒ๐ถ๐บ๐ฎ๐ด๐ถ๐ป๐ฒ๐ฑ ๐ฎ๐ป๐ฑ ๐ฟ๐ฒ๐ฏ๐ฟ๐ฎ๐ป๐ฑ๐ฒ๐ฑ ๐ฎ๐ ๐๐ต๐ฒ ๐๐ถ๐ด๐ด๐ฒ๐ฟ, ๐๐ผ๐น๐ฑ๐ฒ๐ฟ ๐-๐ฆ๐ฝ๐ฎ๐ป ๐ฆ๐๐บ๐บ๐ถ๐, ๐ถ๐ป๐๐ฝ๐ถ๐ฟ๐ฒ๐ฑ ๐ฏ๐ ๐ผ๐๐ฟ ๐-๐ฆ๐ฝ๐ฎ๐ป ๐ฃ๐ผ๐ฑ๐ฐ๐ฎ๐๐. Weโre thrilled to partner
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Hiring for a Head of Clinical! https://t.co/wZkrV2DIOM Interesting clinical trials to run and novel paths to carve for longevity therapeutics await.
jobs.lever.co
Retro develops therapies for diseases driven by the biology of aging. We focus on cellular reprogramming and autophagy to rejuvenate cell and tissue function with the ultimate aim of adding 10 years...
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Our first human clinical trial, now officially registered! (and starting soon ๐ค) https://t.co/oQQV75EV1R
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how a biologist sees the world
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33 Things I've Learned at 33 https://t.co/4xmauoHhgj
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New in Nature Reviews Genetics: my Review on how advanced genomic technologies are redefining cellular reprogramming: mapping trajectories, dissecting chromatin dynamics, + lineage tracing & synthetic circuits to push the boundaries of cell identity. https://t.co/8NBM5ohxkJ
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inspired by recent events: tomorrow i will publish an article about why you should work in biology because at some point in your lifeโmaybe not today, but somedayโyouโll realize that it is the only field that actually mattered, so you might as well start now
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At @OpenAI, we believe that AI can accelerate science and drug discovery. An exciting example is our work with @RetroBiosciences, where a custom model designed improved variants of the Nobel-prize winning Yamanaka proteins. Today we published a closer look at the breakthrough. โฌ๏ธ
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Ideas people often bring up when discussing automation in biotech: - AI scientists - cloud labs - a shareable format for protocols - vision driven validation systems No one is more excited about these things than I am, but how will we get there without building a decent
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I'm thrilled to share our new paper in Nature Immunology! Spatial proteomics of Alzheimerโs disease-specific human microglial states: https://t.co/VvKI36NhfX โ the culmination of my postdoc at @Stanford @StanfordMed in the @Bendall_Lab and lab of Thomas Montine! ๐ง โจ
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We're just as excited about the new ARPA-H program, FRONT, as you are! It's truly transformative for patients currently suffering from permanent neurological damage with no immediate cure.
NEW: No technology currently exists to repair damaged brain tissue and fully restore lost function. FRONT aims to enable millions with what is considered permanent brain damage to regain lost functions, including motor control, vision, and speech.
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NEW: No technology currently exists to repair damaged brain tissue and fully restore lost function. FRONT aims to enable millions with what is considered permanent brain damage to regain lost functions, including motor control, vision, and speech.
arpa-h.gov
The Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs ranging from molecular to societal to provide transformative...
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Excited to share our new publication! We previously showed that age reversal can be achieved using transcription factor-based reprogramming. Now, we demonstrate that it can also be done with chemical cocktails to achieve lifespan extension! https://t.co/hxgIhAOW0U
link.springer.com
EMBO Molecular Medicine - The dedifferentiation of somatic cells into a pluripotent state by cellular reprogramming coincides with a reversal of age-associated molecular hallmarks. Although...
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Thrilled to have joined Nabil Laoudji (@nabilwrites) on his podcast, Discovery Engines. We talked about the founding story and mission behind PyLabRobot: building open, universal lab automation that empowers scientists everywhere. Check out the episode below!
What if we could integrate, play with, and control lab hardware as easily as we do software? Thatโs the vision behind @pylabrobot, an open-source, hardware-agnostic Python SDK building a universal interface for lab automation. I sat down with its creator, @rickwierenga, to
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What if we could integrate, play with, and control lab hardware as easily as we do software? Thatโs the vision behind @pylabrobot, an open-source, hardware-agnostic Python SDK building a universal interface for lab automation. I sat down with its creator, @rickwierenga, to
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cool to see @davidasinclair share the news article i wrote with some @RetroBio_ scientists about recent work @altos_labs. super excited for the future of partial reprogramming therapies - stay tuned
NEW PAPER: Partial reprogramming with virally-delivered OSK genes rejuvenates senescent cells, restores tissue integrity, heals wounds & extends lifespan in mice. Can't wait to see if it works in humans @lifebiosciences ๐ https://t.co/O7ANo5BDO2
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The biggest obstacle to curing diseases w/ AI is data! Quality & quantity. Bio data pales in comparison to NLP or comp vision. Also, due to scientific fads, existing data likely captures only a sliver of possible info/signal in biology. Data is the key to BioXAI impact!
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Why test #celltherapies one-by-one when you can use multiplexed #SynBio, #proteinengineering & #ML to design, measure & track them at scale? The Goodman Lab @PennMedicine opens July 2025. Weโre hiring Specialists & Postdocs! Apply @ https://t.co/DE7aPLp9vr RTs appreciated!๐
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