Akshay Sharma MD
@AkshaySharmaMD
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Pediatric Bone Marrow Transplant @StJudeResearch #GeneTx #GenomeEditing #SickleCell Tweets and opinions are my own ≠ medical advice. COI: https://t.co/jfz4xGdu7N
Memphis, TN
Joined July 2016
#PublicationAlert Incredibly proud to share our manuscript in @NEJM describing the first 3 #SickleCell dz patients who got hematopoietic stem cells #CRISPR Cas9 edited at the globin locus .🙏 to @Seredev1 @jl_labelle @JJ_boelens @janbra1 @MariaCancio3
nejm.org
Sickle cell disease is caused by a defect in the β-globin subunit of adult hemoglobin. Sickle hemoglobin polymerizes under hypoxic conditions, producing deformed red cells that hemolyze and cause v...
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RT @StJudeResearch: New research shows gene therapy improves brain blood flow in sickle cell disease patients, reducing stroke risk. Findin….
stjude.org
Find how gene therapy for sickle cell disease may decrease brain ischemia risk by returning brain blood flow to normal levels according to a clinical trial.
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I hope that our findings will encourage more research in this field to assess the efficacy of these therapies for individuals with SCD who have neurovascular disease or are at risk of stroke.
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Does gene therapy for sickle cell disease improve blood flow to the brain? Our recently published report in @AjHematology shows that it does
onlinelibrary.wiley.com
Click on the article title to read more.
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RT @BloodJournal: This study has identified the impact of HLA alloimmunization in autologous gene-modified hematopoietic cell transplantati….
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RT @VJHemOnc: Will gene therapy transform the future of #SickleCellDisease care?🩸🧬. We've just published a podcast episode in which @Akshay….
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RT @DrGauravNarula: 2012 a friend said- “Science Fiction”.2015 we dared to dream.Sharing 🇮🇳 1st novel #CARTCellRx Ph 1/1b trial.We report 9….
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RT @MSKCME: Sickle Cell Disease is a complex, evolving condition. Join us for a complimentary virtual symposium @MSKCancerCenter featuring….
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RT @BloodAdvances: Nonclinical evaluation of HBG1/2 and BCL11A as genome-editing targets for the treatment of β-hemoglobinopathies https://….
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RT @RabiHannaMD: The Pediatric Rare Disease Priority Review Voucher Program, incentivising pediatric rare diseases including #ChildhoodCanc….
congressweb.com
Would you take a minute to help kids with cancer?Please fill out this form!
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RT @JamesADiao: 🧵1/ Last year, a thoughtful reply to our @JAMA_current article sent me down a rabbit hole on CVD prevention. Should statin….
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RT @spkalantri: Gene therapy offers new hope for sickle cell anemia, surpassing traditional treatments like alloHCT. Can we overcome the co….
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RT @ASTCT_Journal: Explore the latest ASTCT evidence-based guidelines for #alloHCT in severe aplastic anemia (SAA). Key updates include gra….
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RT @BloodJournal: How I treat sickle cell disease with gene therapy.#HowITreat #genetherapy #redcellsironanderythro….
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🚨PublicationAlert🚨 How I Treat Sickle Cell Disease with Gene Therapy, published online () and in print in @BloodJournal .Many thanks to @DrAlexisThompsn @jkw4444 @LakshmananKris7 @shal34982692 @BMTriplettMD and @allistair_2001 for their inputs 🙏
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RT @TheEBMT: 🧵Twitter Thread:🧵.EBMT 2025 Abstract Submission & Opportunities!. 1/ 🚨 Reminder for Physicians, Data Managers, Statisticians,….
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RT @DavidSteensma: If you're a hematologist thinking of making a change, we have a session for you next Sunday at #ASH24: "Symposium for Mi….
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RT @NAChristakis: The bacteria in your gut depend on where you are in the social network. And the microbes within us treat our social netw….
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RT @AlbeenaDr: For all Cell Therapy experts in India & across the APAC region—Academia & Industry! . Don’t miss this unique opportunity to….
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RT @RahulBanerjeeMD: 🚨 due Friday! (Quick) application for @ASTCT committees. Honored for @sghmd and me to be new ASTCT Content Comm chair….
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RT @Taha_CancerDoc: Check out our podcast on Outpatient #CARtcell Administration, I enjoyed the discussion with this expert team. Thank you….
podcasts.apple.com
Podcast Episode · ASTCT Talks · 10/14/2024 · 37m
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