The updated @ASTCT Practice Guidelines App makes it easier than ever to access clinical tools, GVHD scoring, built-in calculators and more—right at your fingertips. If you haven’t downloaded it yet, now’s the time:

This study reports outcomes of non-myeloablative (NMA) #alloHCT for myelofibrosis in Eastern Denmark. NMA regimens showed satisfactory survival, with low one-year non-relapse mortality but high relapse risk. Read more:

Now that gene therapies for SCD & TDT are commercially available, institutions are sharing best practices to optimize care. This review outlines key assessments, patient journey insights & supportive care for autologous gene therapy. Read the review:

July is Cord Blood Awareness Month! 🧬 Explore our special collection spotlighting the latest research, innovations and clinical advances in cord blood transplantation and cellular therapy. Read the collection: #CordBloodAwarenessMonth

This article reflects on the growing number of cancer & transplant survivors & the moral obligation to help them thrive. Long-term follow-up, survivorship care & adherence to research are key to ensuring a life saved becomes a life well-lived. Read more:

In this study, the 1-year incidence of infectious enterocolitis after #HCT with post-transplant cyclophosphamide was 19%. Bone marrow grafts and chronic #GVHD increased risk, but infectious enterocolitis did not affect overall transplant outcomes.

High melphalan exposure increases the risk of engraftment syndrome and Grades II–IV acute #GVHD in pediatric patients undergoing T-cell depleted haploidentical transplantation. Many patients may need adjustments to BSA-based melphalan dosing. Read more:

This study found that allogeneic stem cell transplantation after pembrolizumab therapy l—including for classical Hodgkin lymphoma—showed favorable progression-free and overall survival with low relapse and transplant-related mortality. Read more:

Streamlined society-led training, centralized safety reporting and accreditor oversight could replace FDA-mandated #CART REMS. ASTCT’s 80/20 group recommends retiring redundant REMS to improve safety tracking and expand access to cell therapies. Read:

This study found that granulocyte colony-stimulating factor (G-CSF) accelerated neutrophil recovery after BMT, PBSCT and CBT for adult #MDS. Late G-CSF improved OS after PBSCT but increased chronic #GVHD risk after PBSCT and CBT. Read more:

Children with chronic #GVHD after #HCT face atypical presentation, higher morbidity and long-term immune effects. This RESILIENT conference report highlights the need for tailored monitoring, improved diagnostics and age-specific strategies for recovery

A new clinical grading system for xeno-GVHD in immunodeficient mice offers a simple, reproducible way to assess disease severity. This clinical grading system correlates with 3 histological, 13 cellular and 4 cytokine markers of #GVHD in humans. Read:

Motor and activity assessments revealed that pomalidomide may improve function in steroid-refractory cGVHD. At 6 months, patients showed gains in mobility, hand skills and quality of life. Read the full article:

The June issue of 'Transplantation and Cellular Therapy' is now available online. Check out the latest research in transplantation, cellular therapy and more: .@ELShematology

Drawn from a supplement issue dedicated to the latest research, challenges and innovations in chronic GVHD (cGVHD) management, this review covers the pathophysiology, presentation, diagnosis and treatment of ocular GVHD (oGVHD).

ICYMI: The @ASTCTJournal has released a new supplement dedicated to the latest research, challenges and innovations in tumor-infiltrating lymphocyte (#TIL) therapy, supported through an educational grant provided by Iovance Biotherapeutics. View now:

This study’s data demonstrate that cell-mediated immunity to the influenza vaccine can be elicited in patients vaccinated pre-CAR-T and sustained post-CAR-T. Read the full study:

Carl June is one name that reshaped medicine. This tribute article charts his journey from Navy doctor to #CART pioneer, highlighting how his vision and compassion launched a new era of cellular therapy and saved thousands of lives. Read the article:

High amphiregulin (AREG) expression was found in intestinal biopsies of pediatric patients with severe #GVHD and IBD. AREG levels correlated with inflammation severity, suggesting its potential as a biomarker for severe GVHD in children. Read more:

Two nonmyeloablative HLA-matched #alloHCT regimens for severe sickle cell disease show high survival and stable mixed myeloid chimerism. Read the full study: