Adam J. Engler
@AdamEnglerUCSD
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Husband | Dad | Bioengineering Professor & Chair of @ucsdbe | Cancer and Cardiovascular Mechanobiology | Assoc. Editor, @aplbioeng | he/him/his
La Jolla, CA
Joined June 2014
WE HAVE A NEW NAME!!!!! Thanks to @UCSDJacobs, @ucsdbe, and all of our amazing staff, students, and faculty. Thank you to Shu Chien for his leadership, and especially @BioLegend CEO Gene Lay for this transformational gift.
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Thanks to our faculty contributors: @ChristmanLab, @ContijochResLab, @StimulatedRaman, @reemkhojah, @FraleyLab, @esterjkwon, @KunZhangBioE, @kiana_aran, @ChapelinFanny, @ELCyphert_PhD, @KnightLabNews, @KravetsVira, @prashantgmali, and more!
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👇👇👇👇Just Released👇👇👇👇 The 2025 Impact Report for @UCSDJacobs's Chien-Lay Department of #Bioengineering is out!!!! Amazing updates from @ucsdbe students, faculty, and staff. #TritonPride
https://t.co/wfSWOTCvXD
heyzine.com
Created with the Heyzine flipbook maker
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Thanks to Cassie Happe and Ludovic Vincent from @UCSDJacobs and @ucsdbe for the help over many years to make the durotactic substrates used in the paper. Many, many others to thanks, especially @NIH for funding. (4/4)
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Disruption of this pathway through genetic or pharmacological inhibition blocks durotaxis and attenuates disease severity, highlighting anti-durotactic therapy as a promising treatment strategy. (3/4)
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#Durotaxis-the migration of cells along stiffness gradients-actively drives disease progression in vivo by promoting fibroblast recruitment in lung fibrosis and metastatic spread in pancreatic cancer. This processes requires FAK–paxillin–YAP signaling. (2/4)
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🎉Just published a cool story in @NatureCellBio with @dtschump1 (@MayoClinic ) and @david_lagares (@harvardmed and Zenon Biotech) on #durotaxis. https://t.co/tnOK3PR28N (1/4)
nature.com
Nature Cell Biology - Al-Hilal, Chrysovergi et al. identify a role for durotaxis in lung fibrosis and metastatic pancreatic cancer, mediated by the FAK–paxillin mechanosensor complex, and...
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#ICYMI: Very cook iPSC-organoid paper to create an engineered neural progenitor cell niche. Via @unifesp and Marimelia Porcionatto's lab in @aplbioeng: https://t.co/scgo1nPUBM
pubs.aip.org
Animal models, especially rodents, used to study neurodevelopment have significantly advanced our comprehension of cellular and molecular mechanisms. Neverthele
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Registration is now open for the inaugural Female Athlete Research Meeting (FARM) at Stanford! Spots are limited. Join us on Nov. 5, 2025, for a day dedicated to advancing women & girls in sport through research, collaboration, & innovation. #FARM2025
https://t.co/qTnXZmz1eN
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New article online: Trionic all-optical biological voltage sensing via quantum statistics. https://t.co/ADklJEOtWE
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Did you know that NIH funded the development of 354 out of 356 drugs that were approved from 2010-2019? Only 2 were privately funded. The same NIH with a proposed 40% budget cut. What are we doing to medical innovation? Gift article link below…🎁💉 https://t.co/ynNPU1lEQL
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New #paper out 📢 Can brain signals predict long-term motor recovery after stroke? Using brain signals recorded 2 days post-stroke + machine learning, we predicted 1-month recovery with 94% accuracy. Read more here: https://t.co/agIi7tCAEw
#Stroke #Neuroscience #BrainSignals
pubs.aip.org
Stroke remains a leading cause of long-term disability, underscoring the urgent need for effective predictors of motor recovery. Understanding the electrophysio
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***Huge congratulations*** to 111 M.S. and M.Eng. graduates from the Chien-Lay Department of #Bioengineering (@ucsdbe) and the @UCSDJacobs. #Tritons2025 #Graduation 🎓 Up next: 131 B.S. graduates on Saturday/Sunday and 28 Ph.D. graduates on Sunday!
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I'm a Survinin! New @APLBioeng paper from @YonghoBae2 and @UB_BME reveals survivin's impact on the modulation of cell phenotype & proliferation. #mechanobiology
pubs.aip.org
Stiffened arteries are a pathology of atherosclerosis, hypertension, and coronary artery disease and a key risk factor for cardiovascular disease events. The in
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Efficient, cost-effective, and highly tunable molecular engineered DNA microladder-based soft hydrogels - super cool! (@KAUST) #DNA, #hydrogels, #biomaterials, #molecularengineering
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Super proud moment for everyone in the lab! Our PI @AdamEnglerUCSD appointed as the Kenneth Bowles Endowed Chair in @UCSDJacobs @ucsdbe
#gradschool #phdlife
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Congrats to @Daniela_ValdezJ on her @aimbe induction! Well deserved! Your @ucsdbe and @UCSDJacobs colleagues are very proud of your amazing #PAH research.
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Congrats to Gene Lay, CEO of @BioLegend and namesake of @ucsdbe, on his induction to @aimbe - well deserved! Congratulations from all at @UCSDJacobs
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Researchers at @UCSDHealth have found a potential way to predict the spread of early-stage breast cancer 🧫 In a study released in @CellReports, @AdamEnglerUCSD and Anne Wallace, MD, detail a promising new way oncologists can tailor patients' treatments and improve outcomes.
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See AIMBE's new fact sheets highlighting the NIH & NSF as economic engines at https://t.co/Glwd0bcdDE! Every $1 in NIH research funding yielded $2.56 in new economic activity in the U.S. NIH-funded research also supported over 400,000 jobs across the nation in FY2024 🦾
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