Zu-Hang Sheng
@zuhangsheng
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A neuroscientist at NINDS/NIH studying neuronal mitochondria/lysosomes and energy metabolism. Opinions are my own. https://t.co/4myWbN5PZg
Joined July 2019
Pleased to share our invited News & Views piece in @NatMetabolism, highlighting the emerging role of lipid metabolism in fueling synaptic transmission. Grateful to @sunan_li for co-authoring this contribution with me.
Fuelling synapses via lipid metabolism
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We are delighted that our recent review has been included in the JCB Cellular Neurobiology 2024 Special Collection.
Xiong and @zuhangsheng review recent advances in presynaptic mechanisms of neurodevelopmental disorders by focusing on impaired axonal transport of presynaptic cargos. đź“™ In our Cellular Neurobiology collection: #SfN24 #Neuroscience
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thrilled to share our latest review discussing presynaptic perspectives of neurodevelopmental disorders by focusing on impaired axonal transport and disturbed assembly and maintenance of presynapses.
Presynaptic perspective: Axonal transport defects in neurodevelopmental disorders. New review from Gui-Jing Xiong and Zu-Hang Sheng (@zuhangsheng) @NIH_NINDS: #Trafficking #Neuroscience
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Delighted to share our review. Congrats to Gui-Jing Xiong! Thank JCB editor @andrea_marat for handling this review so well, and the reviewers who provided constructive comments. Very happy to publish with @JCellBiol.
New review: Xiong and Sheng @zuhangsheng @NIH_NINDS summarize recent advances in presynaptic mechanisms of neurodevelopmental disorders by focusing on impaired axonal transport of presynaptic cargos. #Trafficking #Neuroscience
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Really Fun visiting UNC Chapel Hill and meeting faculty and graduate students in Department of Pharmacology. Many thanks to Juan Song @Songlaboratory for hosting. It was great hearing about all of exciting research form the Song Lab and others!.
My great pleasure to host Dr. Zuhang Sheng @zuhangsheng from NIH for an inspiring seminar on mitochondrial reprogramming and energy metabolism for neuroregeneration @UNC_PHCO.
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I am shocked and saddened to learn of the passing of Bill Catterall, my postdoc mentor and a pioneer and giant in ion channel research. It is a great loss for science.
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RT @NIHOxCam: Thrilled to share that #NIHOxCam scholar @aditi_k37 recently passed her First Year Report!! Aditi is co-mentored by @zuhangsh….
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Delighted to share our review led by @sunan_li and invited by co-editors @inna_slutsky and RH Swerdlow. We overview recent advances in how oligodendrocytes support axonal energy metabolism in health and neurological disorders.
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RT @cell_club: TRAK adaptors regulate the recruitment and activation of dynein and kinesin in mitochondrial transport..
nature.com
Nature Communications - The mechanisms of microtubule-based mitochondrial transport remain poorly understood. Here, the authors show that the mitochondrial TRAK adaptors activate the...
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RT @JCellBiol: .@zuhangsheng et al review how axonal endolysosomal trafficking, distribution, and lysosomal functionality support neuronal….
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RT @alessio_vagnoni: . including an intriguing role for Syntaphilin in reducing Split-Miro-dependent fly hyperactivity @zuhangsheng. The u….
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RT @Michael_E_Ward_: We have liftoff! Great overviews of the official launch of the iPSC Neurodegenerative Disease Initiative (iNDI). Large….
nia.nih.gov
Researchers can obtain stem cells that NIH Center for Alzheimer’s and Related Dementias (CARD) scientists have specially engineered for studying the genes behind Alzheimer’s disease several other...
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Congratulations to Sunan @sunan_li for winning NINDS Image Contest.
In this image, Susan Li @sunan_li (PI @zuhangsheng) captured mature excitatory neurons that had been differentiated from pluripotent stem cells. Great progress—the lap started working with human iPSCs just six months ago!
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Thanks to a great collaborative effort with Neuron editors @NeuroCellPress, and @XiutangC, @nigg_huang. The maintenance of axonal mitochondria & energy metabolism is one of the most interesting topics to power neuronal survival, function, & regeneration.
In this issue's free featured #Review by @XiutangC, @nigg_huang & @zuhangsheng, learn how neurons maintain axonal mitochondria & about potential strategies that target bioenergetic restoration to power neuronal survival, function, & regeneration.
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Happy to share a featured review out in the new issue @NeuroCellPress on Programming axonal mitochondrial maintenance and bioenergetics in neurodegeneration and regeneration. Congrats to @XiutangC, @nigg_huan, and the Sheng Lab:
cell.com
Cheng, Huang, and Sheng review recent advances in how neurons maintain a healthy pool of axonal mitochondria to power neuronal function and how energy deficits contribute to neurodegeneration and...
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I am grateful to be one of the highlights in the NINDS Director’s post on the celebration of Asian American, Native Hawaiian, and Pacific Islander Heritage Month 2022.
A note in appreciation for the contributions to the #NINDS mission by scientists of Asian/Pacific Islander/Hawaiian descent.
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RT @ShahrnazKemal: Join us this week for two great #nCyto talks by Sandhya Koushika and Zu-Hang Sheng! Thursday, May 5. Register at https:/….
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Check out our review in @NeuroCellPress, contributed by @XiutangC and @nigg_huang. We overview recent advances in how neurons maintain a healthy pool of axonal mitochondria and potential strategies that target bioenergetic restoration within axons.
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RT @JCellBiol: Schematic diagram showing motor–adaptor complexes mediating kinesin and dynein motor recruitment to LE/LY membranes for MT-b….
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RT @sydneyecason: Very excited we have a new preprint out! This was a joint effort between @koslovergroup @SaurabhMogre @ErikaHolzbaur and….
biorxiv.org
Macroautophagy is a homeostatic process required to clear cellular waste including aggregated proteins and dysfunctional organelles. Neuronal autophagosomes form constitutively in the distal tip of...
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